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GRIA1 recombinant protein :: Glutamate receptor 1 (GRIA1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS968151 GRIA1 recombinant protein
Unit / Price
1 mg (E-Coli)  /  $1,170 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,835 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Glutamate receptor 1 (GRIA1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Glutamate receptor 1 (GRIA1) , partial

 Product Gene Name   

GRIA1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    138248
 3D Structure    ModBase 3D Structure for P42261
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of GRIA1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for GRIA1. It may not necessarily be applicable to this product.
 NCBI GI #    167001419
 NCBI GeneID    2890
 NCBI Accession #    NP_000818.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000827.3 [Other Products]
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 UniProt Primary Accession #    P42261 [Other Products]
 UniProt Secondary Accession #    Q2NKM6; B7Z2S0; B7Z2W8; B7Z3F6; B7Z9G9; D3DQI4; E7ESV8 [Other Products]
 UniProt Related Accession #    P42261 [Other Products]
 Molecular Weight    102,864 Da
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 NCBI Official Full Name    glutamate receptor 1 isoform 1
 NCBI Official Synonym Full Names    glutamate ionotropic receptor AMPA type subunit 1
 NCBI Official Symbol    GRIA1 [Similar Products]
 NCBI Official Synonym Symbols   
GLUH1; GLUR1; GLURA; GluA1; HBGR1
[Similar Products]
 NCBI Protein Information    glutamate receptor 1
 UniProt Protein Name    Glutamate receptor 1
 UniProt Synonym Protein Names   
AMPA-selective glutamate receptor 1; GluR-A; GluR-K1; Glutamate receptor ionotropic, AMPA 1; GluA1
 UniProt Gene Name    GRIA1 [Similar Products]
 UniProt Synonym Gene Names    GLUH1; GLUR1; GluR-1; GluA1 [Similar Products]
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 NCBI Summary for GRIA1    Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for GRIA1    Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
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 Research Articles on GRIA1    1. This study demonstrated that a significant decrease in the protein level of GluA1 in major depression disorder.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GRIA1 recombinant proteinPathways associated with GRIA1 recombinant protein
 Reference Product  PubMed Publications
 GRIA4 recombinant protein  >8 publications with GRIA1 and GRIA4
 GRIK2 recombinant protein  >6 publications with GRIA1 and GRIK2
 GRID2 recombinant protein  >1 publications with GRIA1 and GRID2
 Products by Pathway  Pathway Diagram
 Activation Of AMPA Receptors Pathway antibodies  Activation Of AMPA Receptors Pathway Diagram
 Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies  Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
Diseases associated with GRIA1 recombinant proteinOrgans/Tissues associated with GRIA1 recombinant protein
 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >17 publications with GRIA1 and Mental Disorders
 Nervous System Diseases Antibodies  >4 publications with GRIA1 and Nervous System Diseases
 Brain Diseases Antibodies  >2 publications with GRIA1 and Brain Diseases
 Neurobehavioral Manifestations Antibodies  >2 publications with GRIA1 and Neurobehavioral Manifestations
 Anxiety Disorders Antibodies  >2 publications with GRIA1 and Anxiety Disorders
 Sexual Dysfunctions, Psychological Antibodies  >2 publications with GRIA1 and Sexual Dysfunctions, Psychological
 Neoplasms Antibodies  >1 publications with GRIA1 and Neoplasms
 Drug Toxicity Antibodies  >1 publications with GRIA1 and Drug Toxicity
 Substance-Related Disorders Antibodies  >1 publications with GRIA1 and Substance-Related Disorders
 Memory Disorders Antibodies  >1 publications with GRIA1 and Memory Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >18 publications with GRIA1 and Brain
 Eye Antibodies  >1 publications with GRIA1 and Eye
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