Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow GRID2  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • AFP Antibody
 • Superoxide Dismutase (SOD) ELISA Kit
 • Mycobaterium tuberculosis CFP10 Antibody
 • Biotinidase (BTD) Recombinant Protein
 • B Cell Activation Factor (BAFF) ELISA Kit
 • Acetylcholine (ACH) ELISA Kit
 • Histamine (His) Antibody
 • Free Fatty Acid Receptor 2 (FFAR2) ELISA Kit
 • CSF1 Recombinant Protein
 • C Reactive Protein (CRP) ELISA Kit
 • anti-human IgG Secondary Antibody
 • TAGLN Recombinant Protein
 • Glycosylphosphatidylinosito l Anchored Molecule Like Protein ... ELISA Kit
 • ASK1 (MAP3K5) Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

GRID2 recombinant protein :: Glutamate receptor delta-2 subunit (GRID2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1173486 GRID2 recombinant protein
Unit / Price
1 mg (E-Coli)  /  $1,375 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,835 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Glutamate receptor delta-2 subunit (GRID2), Recombinant Protein

 Also Known As   

Recombinant Human Glutamate receptor delta-2 subunit (GRID2) , partial

 Product Gene Name   

GRID2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence Positions    24-1007
 Sequence    DSIIHIGAIF DESAKKDDEV FRTAVGDLNQ NEEILQTEKI TFSVTFVDGN NPFQAVQEAC ELMNQGILAL VSSIGCTSAG SLQSLADAMH IPHLFIQRST AGTPRSGCGL TRSNRNDDYT LSVRPPVYLH DVILRVVTEY AWQKFIIFYD SEYDIRGIQE FLDKVSQQGM DVALQKVENN INKMITTLFD TMRIEELNRY RDTLRRAILV MNPATAKSFI TEVVETNLVA FDCHWIIINE EINDVDVQEL VRRSIGRLTI IRQTFPVPQN ISQRCFRGNH RISSTLCDPK DPFAQNMEIS NLYIYDTVLL LANAFHKKLE DRKWHSMASL SCIRKNSKPW QGGRSMLETI KKGGVSGLTG ELEFGENGGN PNVHFEILGT NYGEELGRGV RKLGCWNPVT GLNGSLTDKK LENNMRGVVL RVVTVLEEPF VMVSENVLGK PKKYQGFSID VLDALSNYLG FNYEIYVAPD HKYGSPQEDG TWNGLVGELV FKRADIGISA LTITPDRENV VDFTTRYMDY SVGVLLRRAE KTVDMFACLA PFDLSLWACI AGTVLLVGLL VYLLNWLNPP RLQMGSMTST TLYNSMWFVY GSFVQQGGEV PYTTLATRMM MGAWWLFALI VISSYTANLA AFLTITRIES SIQSLQDLSK QTEIPYGTVL DSAVYEHVRM KGLNPFERDS MYSQMWRMIN RSNGSENNVL ESQAGIQKVK YGNYAFVWDA AVLEYVAIND PDCSFYTIGN TVADRGYGIA LQHGSPYRDV FSQRILELQQ NGDMDILKHK WWPKNGQCDL YSSVDTKQKG GALDIKSFAG VFCILAAGIV LSCFIAMLET WWNKRKGSRV PSKEDDKEID LEHLHRRVNS LCTDDDSPHK QFSTSSIDLT PLDIDTLPTR QALEQISDFR NTHITTTTFI PEQIQTLSRT LSAKAASGFT FGNVPEHRTG PFRHRAPNGG FFRSPIKTMS SIPYQPTPTL GLNLGNDPDR GTSI
 OMIM    602368
 3D Structure    ModBase 3D Structure for O43424
Section Bar
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
Section Bar
 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
Section Bar
 Species    Homo sapiens (Human)
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
Section Bar
 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of GRID2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for GRID2. It may not necessarily be applicable to this product.
 NCBI GI #    558472748
 NCBI GeneID    2895
 NCBI Accession #    NP_001273767.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001286838.1 [Other Products]
Section Bar
 UniProt Primary Accession #    O43424 [Other Products]
 UniProt Secondary Accession #    Q4KKU8; Q4KKU9; Q4KKV0; Q59FZ1; E9PH24 [Other Products]
 UniProt Related Accession #    O43424 [Other Products]
 Molecular Weight    102,822 Da
Table BarTOPTable Bar
 NCBI Official Full Name    glutamate receptor ionotropic, delta-2 isoform 2
 NCBI Official Synonym Full Names    glutamate ionotropic receptor delta type subunit 2
 NCBI Official Symbol    GRID2 [Similar Products]
 NCBI Official Synonym Symbols   
GluD2; SCAR18
[Similar Products]
 NCBI Protein Information    glutamate receptor ionotropic, delta-2
 UniProt Protein Name    Glutamate receptor ionotropic, delta-2
 Protein Family    Glutamate receptor ionotropic
 UniProt Gene Name    GRID2 [Similar Products]
 UniProt Synonym Gene Names    GLURD2; GluD2; GluR delta-2 subunit [Similar Products]
Section Bar
 NCBI Summary for GRID2    The protein encoded by this gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause cerebellar ataxia in humans. [provided by RefSeq, Apr 2014]
Section Bar
 UniProt Comments for GRID2    Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. Promotes synaptogenesis and mediates the D-Serine-dependent long term depression signals and AMPA receptor endocytosis of cerebellar parallel fiber-Purkinje cell (PF-PC) synapses through the beta-NRX1-CBLN1-GRID2 triad complex (PubMed:27418511).
Table BarTOPTable Bar
 Research Articles on GRID2    1. Report on a consanguineous family with autosomal recessive childhood onset of cerebellar ataxia and delayed psychomotor development. Using whole exome sequencing we identified a novel homozygous missense variant [c.2128C > T, p.(Arg710Trp)] in GRID2 that segregates with the disease. The missense variant is located in a conserved region encoding the extracellular serine-binding domain of the GluD2 protein.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with GRID2 recombinant proteinPathways associated with GRID2 recombinant protein
 Reference Product  PubMed Publications
 GRIK2 recombinant protein  >1 publications with GRID2 and GRIK2
 CBLN1 recombinant protein  >1 publications with GRID2 and CBLN1
 GRIA1 recombinant protein  >1 publications with GRID2 and GRIA1
 Products by Pathway  Pathway Diagram
 Long-term Depression Pathway antibodies  Long-term Depression Pathway Diagram
 Long-term Depression Pathway antibodies  Long-term Depression Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
Diseases associated with GRID2 recombinant proteinOrgans/Tissues associated with GRID2 recombinant protein
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >12 publications with GRID2 and Brain Diseases
 Nervous System Diseases Antibodies  >11 publications with GRID2 and Nervous System Diseases
 Nerve Degeneration Antibodies  >4 publications with GRID2 and Nerve Degeneration
 Movement Disorders Antibodies  >3 publications with GRID2 and Movement Disorders
 Disease Models, Animal Antibodies  >2 publications with GRID2 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >1 publications with GRID2 and Cardiovascular Diseases
 Weight Loss Antibodies  >1 publications with GRID2 and Weight Loss
 Substance-Related Disorders Antibodies  >1 publications with GRID2 and Substance-Related Disorders
 Brain Injuries Antibodies  >1 publications with GRID2 and Brain Injuries
 Paralysis Antibodies  >1 publications with GRID2 and Paralysis
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >23 publications with GRID2 and Brain
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions