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Gstp1 recombinant protein :: Glutathione S-transferase P 1 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS952294
SDS-PAGE
Unit / Price
0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
0.01 mg (Yeast)  /  $110 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $190 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
0.1 mg (Yeast)  /  $285 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $460 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $750 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $905 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,140 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,145 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,180 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,650 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,740 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,200 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Glutathione S-transferase P 1 (Gstp1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse Glutathione S-transferase P 1

 Product Synonym Names    GST YF-YFGST class-pi; GST-piB; Preadipocyte growth factor
 Product Gene Name   

Gstp1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    2-210aa; Full Length
 Sequence    PPYTIVYFPV RGRCEAMRML LADQGQSWKE EVVTIDTWMQ GLLKPTCLYG QLPKFEDGDL TLYQSNAILR HLGRSLGLYG KNQREAAQMD MVNDGVEDLR GKYVTLIYTN YENGKNDYVK ALPGHLKPFE TLLSQNQGGK AFIVGDQISF ADYNLLDLLL IHQVLAPGCL DNFPLLSAYV ARLSARPKIK AFLSSPEHVN RPINGNGKQ
 3D Structure    ModBase 3D Structure for P19157
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Gstp1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for Gstp1 recombinant protein

   Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Can metabolize 1-chloro-2,4-dinitrobenzene. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.
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 SDS-PAGE of Gstp1 recombinant protein    Gstp1 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Gstp1. It may not necessarily be applicable to this product.
 NCBI GI #    10092608
 NCBI GeneID    14870
 NCBI Accession #    NP_038569.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_013541.1 [Other Products]
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 UniProt Primary Accession #    P19157 [Other Products]
 UniProt Secondary Accession #    Q8BNY4 [Other Products]
 UniProt Related Accession #    P19157 [Other Products]
 Molecular Weight    39.5kD
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 NCBI Official Full Name    glutathione S-transferase P 1
 NCBI Official Synonym Full Names    glutathione S-transferase, pi 1
 NCBI Official Symbol    Gstp1 [Similar Products]
 NCBI Official Synonym Symbols   
GstpiB
[Similar Products]
 NCBI Protein Information    glutathione S-transferase P 1
 UniProt Protein Name    Glutathione S-transferase P 1
 UniProt Synonym Protein Names   
GST YF-YF; GST class-pi; GST-piB; Preadipocyte growth factor
 Protein Family    Glutathione S-transferase
 UniProt Gene Name    Gstp1 [Similar Products]
 UniProt Synonym Gene Names    Gstpib; Gst P1 [Similar Products]
 UniProt Entry Name    GSTP1_MOUSE
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 UniProt Comments for Gstp1    GSTP1: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. Homodimer. Interacts with CDK5. Belongs to the GST superfamily. Pi family.

Protein type: Transferase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 2.5.1.18; Other Amino Acids Metabolism - glutathione

Cellular Component: cytoplasm; cytosol; extracellular space; intracellular; mitochondrion; nucleus; plasma membrane; protein complex; vesicle

Molecular Function: drug binding; glutathione binding; glutathione transferase activity; JUN kinase binding; kinase regulator activity; protein binding; protein kinase binding; transferase activity

Biological Process: glutathione metabolic process; metabolic process; negative regulation of acute inflammatory response; negative regulation of apoptosis; negative regulation of biosynthetic process; negative regulation of fibroblast proliferation; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of interleukin-1 beta production; negative regulation of JNK activity; negative regulation of nitric-oxide synthase biosynthetic process; negative regulation of stress-activated MAPK cascade; negative regulation of tumor necrosis factor production; positive regulation of superoxide release; regulation of stress-activated MAPK cascade; response to reactive oxygen species
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Product References and Citations for Gstp1 recombinant protein

   A cDNA sequence coding a class pi glutathione S-transferase of mouse.Hatayama I., Satoh K., Sato K.Nucleic Acids Res. 18:4606-4606(1990) Isolation and characterization of two mouse PI class glutathione S-transferase genes.Bammler T.K., Smith C.A.D., Wolf R.C.Biochem. J. 298:385-390(1994) Two murine GSTpi genes are arranged in tandem and are differentially expressed.Xu X., Stambrook P.J.J. Biol. Chem. 269:30268-30273(1994) Molecular cloning of mouse preadipocyte growth factor.Kawada T., Aoki N., Kamei Y., Sugimoto E. Lubec G., Klug S., Kang S.U.Submitted (APR-2007) to UniProtKB Purification, mass spectrometric characterization, and covalent modification of murine glutathione S-transferases.Mitchell A.E., Morin D., Lame M.W., Jones A.D.Chem. Res. Toxicol. 8:1054-1062(1995) SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.Mol. Cell 50:919-930(2013) Molecular structure at 1.8 A of mouse liver class pi glutathione S-transferase complexed with S-(p-nitrobenzyl) glutathione and other inhibitors.Garcia-Saez I., Parraga A., Phillips M.F., Mantle T.J., Coll M.J. Mol. Biol. 237:298-314(1994) The three-dimensional structure of Cys-47-modified mouse liver glutathione S-transferase P1-1. Carboxymethylation dramatically decreases the affinity for glutathione and is associated with a loss of electron density in the alphaB-310B region.Vega M.C., Walsh S.B., Mantle T.J., Coll M.J. Biol. Chem. 273:2844-2850(1998)
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 Research Articles on Gstp1    1. These observed differences contribute to our understanding of how genetic ablation of GSTP causes different levels of myeloproliferation and migration [corrected]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Gstp1 recombinant proteinPathways associated with Gstp1 recombinant protein
 Reference Product  PubMed Publications
 Gstt1 recombinant protein  >958 publications with Gstp1 and Gstt1
 Jun recombinant protein  >539 publications with Gstp1 and Jun
 Cyp1a1 recombinant protein  >289 publications with Gstp1 and Cyp1a1
 Rassf1 recombinant protein  >95 publications with Gstp1 and Rassf1
 Trp53 recombinant protein  >90 publications with Gstp1 and Trp53
 Timp3 recombinant protein  >54 publications with Gstp1 and Timp3
 Egfr recombinant protein  >31 publications with Gstp1 and Egfr
 Mapk8 recombinant protein  >4 publications with Gstp1 and Mapk8
 Fancc recombinant protein  >3 publications with Gstp1 and Fancc
 Products by Pathway  Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Detoxification Of Reactive Oxygen Species Pathway antibodies  Detoxification Of Reactive Oxygen Species Pathway Diagram
 Diurnally Regulated Genes With Circadian Orthologs Pathway antibodies  Diurnally Regulated Genes With Circadian Orthologs Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Glutathione Conjugation Pathway antibodies  Glutathione Conjugation Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
Diseases associated with Gstp1 recombinant proteinOrgans/Tissues associated with Gstp1 recombinant protein
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >974 publications with Gstp1 and Carcinoma
 Prostatic Neoplasms Antibodies  >337 publications with Gstp1 and Prostatic Neoplasms
 Breast Neoplasms Antibodies  >322 publications with Gstp1 and Breast Neoplasms
 Lung Neoplasms Antibodies  >306 publications with Gstp1 and Lung Neoplasms
 Liver Neoplasms Antibodies  >267 publications with Gstp1 and Liver Neoplasms
 Neoplasms, Experimental Antibodies  >236 publications with Gstp1 and Neoplasms, Experimental
 Nervous System Diseases Antibodies  >200 publications with Gstp1 and Nervous System Diseases
 Disease Progression Antibodies  >193 publications with Gstp1 and Disease Progression
 Stomach Neoplasms Antibodies  >147 publications with Gstp1 and Stomach Neoplasms
 Carcinoma, Hepatocellular Antibodies  >140 publications with Gstp1 and Carcinoma, Hepatocellular
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >784 publications with Gstp1 and Blood
 Liver Antibodies  >730 publications with Gstp1 and Liver
 Lung Antibodies  >540 publications with Gstp1 and Lung
 Prostate Antibodies  >385 publications with Gstp1 and Prostate
 Kidney Antibodies  >208 publications with Gstp1 and Kidney
 Brain Antibodies  >202 publications with Gstp1 and Brain
 Stomach Antibodies  >166 publications with Gstp1 and Stomach
 Skin Antibodies  >112 publications with Gstp1 and Skin
 Intestine Antibodies  >95 publications with Gstp1 and Intestine
 Bone Antibodies  >85 publications with Gstp1 and Bone
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