Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow mGM CSF  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • GPR124 Antibody
 • MRPL47 Antibody
 • Daxx (Ab-668) Antibody
 • Prolylcarboxypeptidase (PRCP) ELISA Kit
 • Calnexin (CNX) ELISA Kit
 • Cytochrome P450 3A4 (CYP3A4) ELISA Kit
 • Heart Fatty Acid Binding Protein (H-FABP) ELISA Kit
 • Soluble Endothelial Protein C Receptor (SEPCR) ELISA Kit
 • Corticosterone ELISA Kit
 • N-Acetyl-beta-D-Glucosamini dase (NAG) ELISA Kit
 • Carboxyhemoglobin (HBCO) ELISA Kit
 • Complement Component 5 (C5) ELISA Kit
 • Lysine ELISA Kit
 • Gm2 Ganglioside Activator Protein (GM2AP) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

mGM CSF recombinant protein :: Granulocyte Macrophage-Colony Stimulating Factor Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS142099 mGM CSF recombinant protein
Unit / Price
0.005 mg  /  $140 +1 FREE 8GB USB
0.02 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $2,870 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Granulocyte Macrophage-Colony Stimulating Factor (mGM CSF), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse Granulocyte Macrophage-Colony Stimulating Factor

 Product Synonym Names    GM CSF Mouse; Granulocyte Macrophage-Colony Stimulating Factor Mouse Recombinant; CSF-2; MGI-1GM; GM-CSF; Pluripoietin-alpha; Molgramostin; Sargramostim
 Product Gene Name   

mGM CSF recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence    The sequence of the first five N-terminal amino acids was determined and was found to be Met-Ala-Pr o-Thr-Arg.
 3D Structure    ModBase 3D Structure for P01587
Section Bar
Section Bar
 Purity/Purification    Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
 Form/Format    GM-CSF Mouse was lyophilized with no additives.
Sterile Filtered White lyophilized (freeze-dried) powder.
Section Bar
 Source    E Coli
 Solubility    It is recommended to reconstitute the lyophilized Granulocyte Macrophage Colony Stimulating Factor in sterile 20mM AcOH (acetic Acid) not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
 Protein Content    GM-CSF quantitation was carried out by two independent methods
1. UV spectroscopy at 280 nm using the absorbency value of 0.765 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics).
2. Analysis by RP-HPLC, using a calibrated solution of GM-CSF as a Reference Standard.
 Biological Activity    The ED50 as determined by the dose-dependant stimulation of the proliferation of murine FDC-P1 cell line is < 0.2 ng/ml, corresponding to a Specific Activity of 5,000,000 IU/mg.
Section Bar
 Preparation and Storage    Lyophilized Granulocyte Macrophage Colony Stimulating Factor although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution GM-CSF should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
 Other Notes    Small volumes of mGM CSF recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for mGM CSF recombinant protein

   Description: Granulocyte Macrophage Colony Stimulating Factor Mouse Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 125 amino acids and having a molecular mass of 14285.35 Dalton.GM-CSF Mouse is purified by proprietary chromatographic techniques.

Introduction: GMCSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
 Product Categories/Family for mGM CSF recombinant protein    CYTOKINES AND GROWTH FACTORS; Growth Factors; Colony Stimulating Factor
NCBI/Uniprot data below describe general gene information for mGM CSF. It may not necessarily be applicable to this product.
 NCBI GI #    110625658
 NCBI GeneID    12981
 NCBI Accession #    NP_034099.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_009969.4 [Other Products]
Section Bar
 UniProt Primary Accession #    P01587 [Other Products]
 UniProt Related Accession #    P01587 [Other Products]
 Molecular Weight    16,091 Da
Table BarTOPTable Bar
 NCBI Official Full Name    granulocyte-macrophage colony-stimulating factor
 NCBI Official Synonym Full Names    colony stimulating factor 2 (granulocyte-macrophage)
 NCBI Official Symbol    Csf2 [Similar Products]
 NCBI Official Synonym Symbols   
Csfgm; GMCSF; Gm-CSf; MGI-IGM
[Similar Products]
 NCBI Protein Information    granulocyte-macrophage colony-stimulating factor; CSF; granulocyte-macrophage colony stimulating factor 2; put. GM-CSF
 UniProt Protein Name    Granulocyte-macrophage colony-stimulating factor
 UniProt Synonym Protein Names   
Colony-stimulating factor; CSF
 UniProt Gene Name    Csf2 [Similar Products]
 UniProt Synonym Gene Names    Csfgm; GM-CSF; CSF [Similar Products]
 UniProt Entry Name    CSF2_MOUSE
Section Bar
 UniProt Comments for mGM CSF    GMCSF: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Belongs to the GM-CSF family.

Protein type: Secreted; Cytokine; Secreted, signal peptide

Cellular Component: extracellular space; extracellular region

Molecular Function: growth factor activity; granulocyte macrophage colony-stimulating factor receptor binding; cytokine activity

Biological Process: negative regulation of cytolysis; epithelial fluid transport; embryonic placenta development; macrophage activation; positive regulation of tyrosine phosphorylation of Stat5 protein; regulation of gene expression; positive regulation of interleukin-23 production; positive regulation of cell proliferation; myeloid dendritic cell differentiation; immune response; positive regulation of DNA replication; regulation of cell proliferation
Table BarTOPTable Bar
 Research Articles on mGM CSF    1. Expression of PPAR-gamma in fetal lung monocytes was dependent on the cytokine GM-CSF. Therefore, GM-CSF has a lung-specific role in the perinatal development of alveolar macrophages through the induction of PPAR-gamma in fetal monocytes.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with mGM CSF recombinant proteinDiseases associated with mGM CSF recombinant protein
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response (BioCarta) Pathway antibodies  Cytokines And Inflammatory Response (BioCarta) Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 G Beta:gamma Signalling Through PI3Kgamma Pathway antibodies  G Beta:gamma Signalling Through PI3Kgamma Pathway Diagram
 G-protein Beta:gamma Signalling Pathway antibodies  G-protein Beta:gamma Signalling Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >41 publications with mGM CSF and Inflammation
 Necrosis Antibodies  >26 publications with mGM CSF and Necrosis
 Lung Diseases Antibodies  >9 publications with mGM CSF and Lung Diseases
 Breast Neoplasms Antibodies  >7 publications with mGM CSF and Breast Neoplasms
 Fibrosis Antibodies  >4 publications with mGM CSF and Fibrosis
 Neoplasms, Experimental Antibodies  >4 publications with mGM CSF and Neoplasms, Experimental
 Carcinoma Antibodies  >3 publications with mGM CSF and Carcinoma
 Leukemia, Myeloid, Acute Antibodies  >3 publications with mGM CSF and Leukemia, Myeloid, Acute
 Arthritis, Rheumatoid Antibodies  >3 publications with mGM CSF and Arthritis, Rheumatoid
 Lung Neoplasms Antibodies  >3 publications with mGM CSF and Lung Neoplasms
Organs/Tissues associated with mGM CSF recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >12 publications with mGM CSF and Lung
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions