Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow GH1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • A-L-Iduronidase (IDUA) ELISA Kit
 • CD11a Antibody
 • Angiopoietin 2 (ANG2) ELISA Kit
 • Noradrenaline, NA ELISA Kit
 • SOCS3 Antibody
 • cyclin-dependent kinase 5 (CDK5) ELISA Kit
 • Calcitonin Receptor (CTR) ELISA Kit
 • Dehydroepiandrosterone, DHEA ELISA Kit
 • TNNI3 interacting kinase (TNNI3K) ELISA Kit
 • 1- (5-phosphoribosyl)-5-[ (5-phosphoribosylamino)meth ylidene... Recombinant Protein
 • Plakophilin 2 (PKP2) Recombinant Protein
 • Apolipoprotein B-48-100 (Apo B-48-100) (APOB) Antibody
 • MTUS1 Antibody
 • surfactant protein D (SP-D) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

GH1 recombinant protein :: Growth Hormone (rHuGH) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS197008 GH1 recombinant protein
Unit / Price
0.1 mg  /  $195 +1 FREE 8GB USB
0.5 mg  /  $280 +1 FREE 8GB USB
1 mg  /  $395 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Growth Hormone (rHuGH) (GH1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Growth Hormone

 Product Synonym Names    Recombinant Human Growth Hormone (rHuGH)
 Product Gene Name   

GH1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Chromosome Location    Chromosome: 17; NC_000017.10 (61994563..61996198, complement). Location: 17q24.2
 OMIM    139250
 3D Structure    ModBase 3D Structure for P01241
Section Bar
 Host    E Coli
Section Bar
 Specificity    Recombinant Human Growth Hormone (rHuGH)
 Purity/Purification    Greater than 98% by RP-HPLC, anion-exchange chromatography; reducing and non-reducing SDS-PAGE, silver stain.
Purification: Chromatographic
 Form/Format    Sterile filtered, lyophilized.
Section Bar
 Dimers/Aggregates    <1% by SDSPAGE
 Biological Activity    Fully biologically active compared to the WHO reference standard at 3 Units/mg.
 Endotoxin Level    <0.1 ng/ug
 Protein Content    Determined spectrophotometrically at 280nm (0.72 ext. coeff), and by RP-HPLC analysis against a calibrated standard.
 Solubility    Reconstitute the lyophilized product in sterile water not less than 100 ug/ml.
 Stabilizer    None
 Preservatives    None
Section Bar
 Preparation and Storage    Lyophilized product is stable at room temperature for 3 weeks. Store lyophilized product desiccated at -20 degree C. Upon reconstitution, store at 4 degree C for 2-7 days or aliquot and store at -20 degree C. For long-term storage add either HSA or BSA to 0.1%. Avoid repeated freeze-thaw cycles.
 Other Notes    Small volumes of GH1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for GH1 recombinant protein

   Recombinant Human Growth Hormone produced in E. coli is a single, nonglycosylated polypeptide chain containing 192 amino acids with a molecular mass of 22,260 daltons. This product has full biological activity.
 Product Categories/Family for GH1 recombinant protein    Recombinant Proteins
NCBI/Uniprot data below describe general gene information for GH1. It may not necessarily be applicable to this product.
 NCBI GI #    183157
 NCBI GeneID    2688
Section Bar
 UniProt Primary Accession #    P01241 [Other Products]
 UniProt Secondary Accession #    Q14405; Q16631; Q5EB53; Q9HBZ1; Q9UMJ7; Q9UNL5 [Other Products]
 UniProt Related Accession #    P01241; Q6IYF0; Q6IYF1 [Other Products]
 Molecular Weight    24,847 Da [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    growth hormone
 NCBI Official Synonym Full Names    growth hormone 1
 NCBI Official Symbol    GH1 [Similar Products]
 NCBI Official Synonym Symbols   
GH; GHN; GH-N; hGH-N; IGHD1B
[Similar Products]
 NCBI Protein Information    somatotropin; pituitary growth hormone
 UniProt Protein Name    Somatotropin
 UniProt Synonym Protein Names   
Growth hormone; GH; GH-N; Growth hormone 1; Pituitary growth hormone
 Protein Family    Somatotropin
 UniProt Gene Name    GH1 [Similar Products]
 UniProt Entry Name    SOMA_HUMAN
Section Bar
 NCBI Summary for GH1    The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq]
Section Bar
 UniProt Comments for GH1    GH: Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Defects in GH1 are a cause of growth hormone deficiency isolated type 1A (IGHD1A); also known as pituitary dwarfism I. IGHD1A is an autosomal recessive deficiency of GH which causes short stature. IGHD1A patients have an absence of GH with severe dwarfism and often develop anti-GH antibodies when given exogenous GH. Defects in GH1 are a cause of growth hormone deficiency isolated type 1B (IGHD1B); also known as dwarfism of Sindh. IGHD1B is an autosomal recessive deficiency of GH which causes short stature. IGHD1B patients have low but detectable levels of GH. Dwarfism is less severe than in IGHD1A and patients usually respond well to exogenous GH. Defects in GH1 are the cause of Kowarski syndrome (KWKS); also known as pituitary dwarfism VI. Defects in GH1 are a cause of growth hormone deficiency isolated type 2 (IGHD2). IGHD2 is an autosomal dominant deficiency of GH which causes short stature. Clinical severity is variable. Patients have a positive response and immunologic tolerance to growth hormone therapy. Belongs to the somatotropin/prolactin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Hormone; Secreted

Chromosomal Location of Human Ortholog: 17q24.2

Cellular Component: extracellular space; extracellular region

Molecular Function: protein binding; growth hormone receptor binding; growth factor activity; prolactin receptor binding; metal ion binding; hormone activity

Biological Process: positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of MAP kinase activity; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of tyrosine phosphorylation of Stat5 protein; positive regulation of receptor internalization; positive regulation of JAK-STAT cascade; glucose transport; positive regulation of multicellular organism growth; JAK-STAT cascade; response to estradiol stimulus; positive regulation of tyrosine phosphorylation of Stat3 protein

Disease: Isolated Growth Hormone Deficiency, Type Ia; Isolated Growth Hormone Deficiency, Type Ib; Isolated Growth Hormone Deficiency, Type Ii; Kowarski Syndrome
Table BarTOPTable Bar
 Research Articles on GH1    1. Decreased placental expression of hPGH, IGF-I and IGFBP-1 in pregnancies complicated by fetal growth restriction.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with GH1 recombinant proteinPathways associated with GH1 recombinant protein
 Reference Product  PubMed Publications
 PRLR recombinant protein  >1 publications with GH1 and PRLR
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Diabetes Pathways antibodies  Diabetes Pathways Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Synthesis, Secretion, And Deacylation Of Ghrelin Pathway antibodies  Synthesis, Secretion, And Deacylation Of Ghrelin Pathway Diagram
Diseases associated with GH1 recombinant proteinOrgans/Tissues associated with GH1 recombinant protein
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >63 publications with GH1 and Neoplasms
 Central Nervous System Diseases Antibodies  >50 publications with GH1 and Central Nervous System Diseases
 Thyroid Neoplasms Antibodies  >17 publications with GH1 and Thyroid Neoplasms
 Bone Diseases, Developmental Antibodies  >10 publications with GH1 and Bone Diseases, Developmental
 Skin Diseases Antibodies  >10 publications with GH1 and Skin Diseases
 ISOLATED GROWTH HORMONE DEFICIENCY, TYPE II Antibodies  >9 publications with GH1 and ISOLATED GROWTH HORMONE DEFICIENCY, TYPE II
 Breast Neoplasms Antibodies  >9 publications with GH1 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >8 publications with GH1 and Neoplasms, Experimental
 Adenoma Antibodies  >7 publications with GH1 and Adenoma
 Liver Neoplasms Antibodies  >6 publications with GH1 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Pituitary Gland Antibodies  >42 publications with GH1 and Pituitary Gland
 Brain Antibodies  >39 publications with GH1 and Brain
 Placenta Antibodies  >3 publications with GH1 and Placenta
 Prostate Antibodies  >2 publications with GH1 and Prostate
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions