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oGH recombinant protein :: Growth Hormone Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS142114 oGH recombinant protein
Unit / Price
0.02 mg  /  $140 +1 FREE 8GB USB
0.1 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $580 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Growth Hormone (oGH), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Ovine Growth Hormone

 Product Synonym Names    GH Ovine; Growth Hormone Ovine Recombinant; GH1; GH; GHN; GH-N; hGH-N; Pituitary growth hormone; Growth hormone 1; Somatotropin
 Product Gene Name   

oGH recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    1     afpamslsgl fanavlraqh lhqlaadtfk efertyipeg qrysiqntqv  51    afcf setipa  ptgk neaqqk sdlellrisl lliqswlgpl qflsrvftns  101  lvfg tsdrvy eklkdleegi lalmreledv tpragqilkq tydkfdtnmr  151  sdda llknyg llscfrkdlh ktetylrvmk  crrf geasca f
 3D Structure    ModBase 3D Structure for P67930
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 Host    E Coli
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 Purity/Purification    Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
 Form/Format    The protein was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3.
Sterile Filtered White lyophilized (freeze-dried) powder.
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 Solubility    It is recommended to reconstitute the lyophilized Growth Hormone in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
 Protein Content    Protein quantitation was carried out by two independent methods1. UV spectroscopy at 280 nm using the absorbency value of 0.7 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a calibrated solution of GH as a Reference Standard.
 Biological Activity    The activity as determined by the dose-dependant stimulation of the proliferation FDCP13B9 cells.
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 Preparation and Storage    Lyophilized Growth Hormone although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution GH Ovine should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
 Other Notes    Small volumes of oGH recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for oGH recombinant protein

   Description: Growth Hormone Ovine Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 200 amino acids and having a molecular mass of 22015 Dalton. The GH Ovine Recombinant is purified by proprietary chromatographic techniques.

Introduction: GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
 Product Categories/Family for oGH recombinant protein    CYTOKINES AND GROWTH FACTORS; Growth Factors; Growth Hormone
NCBI/Uniprot data below describe general gene information for oGH. It may not necessarily be applicable to this product.
 NCBI GI #    57527824
 NCBI GeneID    443329
 NCBI Accession #    NP_001009315.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001009315.3 [Other Products]
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 UniProt Primary Accession #    P67930 [Other Products]
 UniProt Secondary Accession #    P01247; P07289; Q29404 [Other Products]
 UniProt Related Accession #    P67930 [Other Products]
 Molecular Weight    24,631 Da
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 NCBI Official Full Name    somatotropin
 NCBI Official Symbol    GH [Similar Products]
 NCBI Official Synonym Symbols   
GH1
[Similar Products]
 NCBI Protein Information    somatotropin; growth hormone 12
 UniProt Protein Name    Somatotropin
 UniProt Synonym Protein Names   
Growth hormone
 Protein Family    Growth hormone
 UniProt Gene Name    GH1 [Similar Products]
 UniProt Entry Name    SOMA_SHEEP
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 UniProt Comments for oGH    Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
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 Research Articles on oGH    1. The effect leptin, orexin-A, and ghrelin on the secretion of luteinizing hormone (LH) and growth hormone by adenohypophyseal explants obtained from normally fed or fasted ewes during the breeding and nonbreeding seasons.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with oGH recombinant proteinDiseases associated with oGH recombinant protein
 Products by Pathway  Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >7276 publications with oGH and Nervous System Diseases
 Pituitary Neoplasms Antibodies  >2940 publications with oGH and Pituitary Neoplasms
 Cardiovascular Diseases Antibodies  >1945 publications with oGH and Cardiovascular Diseases
 Mental Disorders Antibodies  >1150 publications with oGH and Mental Disorders
 Heart Diseases Antibodies  >1068 publications with oGH and Heart Diseases
 Weight Gain Antibodies  >916 publications with oGH and Weight Gain
 Hypertension Antibodies  >735 publications with oGH and Hypertension
 Disease Models, Animal Antibodies  >730 publications with oGH and Disease Models, Animal
 Kidney Diseases Antibodies  >686 publications with oGH and Kidney Diseases
 Urogenital Abnormalities Antibodies  >511 publications with oGH and Urogenital Abnormalities
Organs/Tissues associated with oGH recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Female Genital Antibodies  >633 publications with oGH and Female Genital
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