NP_000811.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,986 Da
NCBI Official Full Name
growth arrest-specific protein 6
NCBI Official Synonym Full Names
growth arrest specific 6
NCBI Official Synonym Symbols
NCBI Protein Information
growth arrest-specific protein 6
UniProt Protein Name
Growth arrest-specific protein 6
UniProt Synonym Protein Names
AXL receptor tyrosine kinase ligand
UniProt Synonym Gene Names
NCBI Summary for GAS6
This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker. Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia. [provided by RefSeq, Aug 2014]
UniProt Comments for GAS6
Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
Research Articles on GAS6
Precautions
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Disclaimer
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Products associated with GAS6 recombinant protein
Pathways associated with GAS6 recombinant protein
Diseases associated with GAS6 recombinant protein
Organs/Tissues associated with GAS6 recombinant protein
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