Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow Guca2b  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • histone deacetylase 4 (HDAC4) ELISA Kit
 • PLLP Antibody
 • (3R)-hydroxymyristoyl-[acyl -carrier-protein] dehydratase (fa... Recombinant Protein
 • LPS-assembly protein lptD (lptD) Recombinant Protein
 • H-ACA ribonucleoprotein complex non-core subunit NAF1 (NAF1) Recombinant Protein
 • Biopyrrin (BPn) ELISA Kit
 • IgG2b Isotype Control
 • AT ELISA Kit
 • L Selectin (SELL) Antibody
 • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 Antibody
 • MMP-2 (MMP2) ELISA Kit
 • S- (hydroxymethyl)glutathione dehydrogenase (fdh) Recombinant Protein
 • macrophage stimulating 1 receptor (MST1R) Antibody
 • Collagen Type III (COL3) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

Guca2b recombinant protein :: Guanylate cyclase activator 2B Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1181049
SDS-PAGE
Unit / Price
0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
0.01 mg (Yeast)  /  $110 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $190 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
0.1 mg (Yeast)  /  $285 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $460 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $750 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $810 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,015 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,045 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,180 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,475 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,600 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $1,980 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Guanylate cyclase activator 2B (Guca2b), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse Guanylate cyclase activator 2B

 Product Gene Name   

Guca2b recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence Positions    22-106aa; Full Length
 Sequence    VYIKYHGFQV QLESVKKLNE LEEKEMSNPQ PRRSGLLPAV CHNPALPLDL QPVCASQEAA STFKALRTIA TDECELCINV ACTGC
 3D Structure    ModBase 3D Structure for O09051
Section Bar
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
Section Bar
 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
Section Bar
Section Bar
 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Guca2b recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for Guca2b recombinant protein

   Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.
Section Bar
 SDS-PAGE of Guca2b recombinant protein    Guca2b recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for Guca2b. It may not necessarily be applicable to this product.
 NCBI GI #    160298221
 NCBI GeneID    14916
 NCBI Accession #    NP_032217.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_008191.2 [Other Products]
Section Bar
 UniProt Primary Accession #    O09051 [Other Products]
 UniProt Related Accession #    O09051 [Other Products]
 Molecular Weight    36.8kD
Table BarTOPTable Bar
 NCBI Official Full Name    guanylate cyclase activator 2B preproprotein
 NCBI Official Synonym Full Names    guanylate cyclase activator 2b (retina)
 NCBI Official Symbol    Guca2b [Similar Products]
 NCBI Official Synonym Symbols   
Ugn; Gcap2; AV066530
[Similar Products]
 NCBI Protein Information    guanylate cyclase activator 2B
 UniProt Protein Name    Guanylate cyclase activator 2B
 Protein Family    Guanylate cyclase activator
 UniProt Gene Name    Guca2b [Similar Products]
 UniProt Synonym Gene Names    UGN [Similar Products]
 UniProt Entry Name    GUC2B_MOUSE
Section Bar
 NCBI Summary for Guca2b    This gene encodes a member of the guanylin family and preproprotein that is proteolytically processed to generate a mature protein product. The mature protein product, known as uroguanylin, is an endogenous ligand for the guanylate cyclase-C receptor and may regulate salt and water homeostasis in the intestine and kidneys. Homozygous knockout mice for this gene exhibit impaired sodium chloride excretion and elevated arterial pressure. This gene is present in a gene cluster with a related guanylin family member on chromosome 4. [provided by RefSeq, Sep 2015]
Section Bar
 UniProt Comments for Guca2b    GUCA2B: Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport. Belongs to the guanylin family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular region; photoreceptor outer segment

Molecular Function: guanylate cyclase activator activity

Biological Process: body fluid secretion; cGMP biosynthetic process; excretion; negative regulation of blood pressure; regulation of cyclic nucleotide biosynthetic process
Table BarTOPTable Bar
 

Product References and Citations for Guca2b recombinant protein

   Uroguanylin and guanylin distinct but overlapping patterns of messenger RNA expression in mouse intestine.Whitaker T.L., Witte D.P., Scott M.C., Cohen M.B.Gastroenterology 113:1000-1006(1997) Sanford L.P., Cohen M.B.
Section Bar
 Research Articles on Guca2b    1. UGN exerts its inhibitory activity on the prendrin gene promoter likely via heat shock factor 1 action at a defined heat shock element site.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with Guca2b recombinant proteinPathways associated with Guca2b recombinant protein
 Reference Product  PubMed Publications
 Guca2a recombinant protein  >2 publications with Guca2b and Guca2a
 Gucy2c recombinant protein  >2 publications with Guca2b and Gucy2c
 Products by Pathway  Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
Diseases associated with Guca2b recombinant proteinOrgans/Tissues associated with Guca2b recombinant protein
 Disease Name  Pubmed Publications
 Hypertension Antibodies  >4 publications with Guca2b and Hypertension
 Cardiovascular Diseases Antibodies  >3 publications with Guca2b and Cardiovascular Diseases
 Prenatal Exposure Delayed Effects Antibodies  >2 publications with Guca2b and Prenatal Exposure Delayed Effects
 Necrosis Antibodies  >1 publications with Guca2b and Necrosis
 Inflammation Antibodies  >1 publications with Guca2b and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >4 publications with Guca2b and Intestine
 Kidney Antibodies  >3 publications with Guca2b and Kidney
 Uterus Antibodies  >1 publications with Guca2b and Uterus
 Embryonic Tissue Antibodies  >1 publications with Guca2b and Embryonic Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions