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GUK1 recombinant protein :: Guanylate kinase Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1476775
Unit / Price
0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $745 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $895 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,000 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,125 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,130 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,135 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,630 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,720 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,725 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,180 +2 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Guanylate kinase (GUK1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Guanylate kinase

 Product Synonym Names    GMP kinase
 Product Gene Name   

GUK1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    2-197aa; Full Length
 OMIM    139270
 3D Structure    ModBase 3D Structure for Q16774
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of GUK1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for GUK1 recombinant protein

   Essential for recycling GMP and indirectly, cGMP.
 Product Categories/Family for GUK1 recombinant protein    Cancer
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 SDS-PAGE of GUK1 recombinant protein    GUK1 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for GUK1. It may not necessarily be applicable to this product.
 NCBI GI #    4504221
 NCBI GeneID    2987
 NCBI Accession #    NP_000849.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000858.5 [Other Products]
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 UniProt Primary Accession #    Q16774 [Other Products]
 UniProt Secondary Accession #    B1ANH1 [Other Products]
 UniProt Related Accession #    Q16774 [Other Products]
 Molecular Weight    37.58kD
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 NCBI Official Full Name    guanylate kinase isoform b
 NCBI Official Synonym Full Names    guanylate kinase 1
 NCBI Official Symbol    GUK1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    guanylate kinase
 UniProt Protein Name    Guanylate kinase
 UniProt Synonym Protein Names   
GMP kinase
 Protein Family    Guanylate kinase
 UniProt Gene Name    GUK1 [Similar Products]
 UniProt Synonym Gene Names    GMK [Similar Products]
 UniProt Entry Name    KGUA_HUMAN
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 NCBI Summary for GUK1    The protein encoded by this gene is an enzyme that catalyzes the transfer of a phosphate group from ATP to guanosine monophosphate (GMP) to form guanosine diphosphate (GDP). The encoded protein is thought to be a good target for cancer chemotherapy. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
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 UniProt Comments for GUK1    GUK1: Essential for recycling GMP and indirectly, cGMP. Belongs to the guanylate kinase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Kinase, other; Nucleotide Metabolism - purine; EC

Chromosomal Location of Human Ortholog: 1q32-q41

Cellular Component: cytosol

Molecular Function: ATP binding; guanylate kinase activity

Biological Process: ATP metabolic process; dATP metabolic process; dGDP biosynthetic process; dGMP metabolic process; drug metabolic process; GDP biosynthetic process; GDP-mannose metabolic process; GMP metabolic process; nucleobase, nucleoside and nucleotide interconversion; nucleobase, nucleoside and nucleotide metabolic process; nucleotide phosphorylation; purine nucleotide metabolic process
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Product References and Citations for GUK1 recombinant protein

   "Human guanylate kinase (GUK1): cDNA sequence, expression and chromosomal localisation." Fitzgibbon J., Katsanis N., Wells D., Delhanty J., Vallins W., Hunt D.M. FEBS Lett. 385:185-188(1996)
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 Research Articles on GUK1    1. HGS and GUK1 were significantly over expressed in GH-secreting adenomas, compared with ACTH-secreting adenomas and nonfunctioning tumors, and with PRL-secreting adenomas, respectively.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GUK1 recombinant proteinPathways associated with GUK1 recombinant protein
 Reference Product  PubMed Publications
 NME1 recombinant protein  >1 publications with GUK1 and NME1
 Products by Pathway  Pathway Diagram
 Abacavir Metabolism Pathway antibodies  Abacavir Metabolism Pathway Diagram
 Abacavir Transport And Metabolism Pathway antibodies  Abacavir Transport And Metabolism Pathway Diagram
 Guanine Ribonucleotide Biosynthesis IMP => GDP,GTP Pathway antibodies  Guanine Ribonucleotide Biosynthesis IMP => GDP,GTP Pathway Diagram
 Guanine Ribonucleotide Biosynthesis IMP => GDP,GTP Pathway antibodies  Guanine Ribonucleotide Biosynthesis IMP => GDP,GTP Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Nucleotides Pathway antibodies  Metabolism Of Nucleotides Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway antibodies  Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway Diagram
Diseases associated with GUK1 recombinant proteinOrgans/Tissues associated with GUK1 recombinant protein
 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >1 publications with GUK1 and Neoplasm Metastasis
 Heart Diseases Antibodies  >1 publications with GUK1 and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3 publications with GUK1 and Blood
 Muscle Antibodies  >1 publications with GUK1 and Muscle
 Heart Antibodies  >1 publications with GUK1 and Heart
 Liver Antibodies  >1 publications with GUK1 and Liver
 Lung Antibodies  >1 publications with GUK1 and Lung
 Brain Antibodies  >1 publications with GUK1 and Brain
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