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H2-K1 recombinant protein :: H-2 class I histocompatibility antigen, K-D alpha chain Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1158913
SDS-PAGE
Unit / Price
0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

H-2 class I histocompatibility antigen, K-D alpha chain (H2-K1), Recombinant Protein

 Also Known As   

Recombinant Mouse H-2 class I histocompatibility antigen, K-D alpha chain

 Product Gene Name   

H2-K1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    22-305aa; Extracellular Domain
 Sequence    GPHSLRYFVT AVSRPGLGEP RFIAVGYVDD TQFVRFDSDA DNPRFEPRAP WMEQEGPEYW EEQTQRAKSD EQWFRVSLRT AQRYYNQSKG GSHTFQRMFG CDVGSDWRLL RGYQQFAYDG RDYIALNEDL KTWTAADTAA LITRRKWEQA GDAEYYRAYL EGECVEWLRR YLELGNETLL RTDSPKAHVT YHPRSQVDVT LRCWALGFYP ADITLTWQLN GEDLTQDMEL VETRPAGDGT FQKWAAVVVP LGKEQNYTCH VHHKGLPEPL TLRWKLPPST VSNT
 3D Structure    ModBase 3D Structure for P01902
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE.
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of H2-K1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for H2-K1 recombinant protein

   Involved in the presentation of foreign antigens to the immune system.
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 SDS-PAGE of H2-K1 recombinant protein    H2-K1 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for H2-K1. It may not necessarily be applicable to this product.
 NCBI GI #    755470377
 NCBI GeneID    101056305
 NCBI Accession #    XP_011241831.1 [Other Products]
 NCBI GenBank Nucleotide #    XM_011243529.1 [Other Products]
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 UniProt Primary Accession #    P01902 [Other Products]
 Molecular Weight    60.4kD
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 NCBI Official Full Name    PREDICTED: H-2 class I histocompatibility antigen, K-D alpha chain isoform X3
 NCBI Official Symbol    LOC101056305 [Similar Products]
 NCBI Protein Information    H-2 class I histocompatibility antigen, K-D alpha chain
 UniProt Protein Name    H-2 class I histocompatibility antigen, K-D alpha chain
 Protein Family    H-2 class I histocompatibility antigen
 UniProt Gene Name    H2-K1 [Similar Products]
 UniProt Synonym Gene Names    H2-K; H-2K(D) [Similar Products]
 UniProt Entry Name    HA1D_MOUSE
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 UniProt Comments for H2-K1    HLAC iso22: Involved in the presentation of foreign antigens to the immune system. Belongs to the MHC class I family.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: cell surface; endoplasmic reticulum; external side of plasma membrane; Golgi apparatus; Golgi medial cisterna; integral to membrane; membrane; MHC class I protein complex

Molecular Function: beta-2-microglobulin binding; peptide antigen binding; peptide binding; protein binding; protein heterodimerization activity; receptor binding; T cell receptor binding; TAP binding

Biological Process: antigen processing and presentation; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent; antigen processing and presentation of exogenous peptide antigen via MHC class I; antigen processing and presentation of peptide antigen via MHC class I; defense response to bacterium; immune response; immune system process; inner ear development; positive regulation of T cell mediated cytotoxicity
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Product References and Citations for H2-K1 recombinant protein

   Mouse histocompatibility genes structure and organisation of a Kd gene.Kvist S., Roberts L., Dobberstein B.EMBO J. 2:245-254(1983) A cDNA clone containing the entire coding sequence of a mouse H-2Kd histocompatibility antigen.Lalanne J.-L., Delarbre C., Gachelin G., Kourilsky P.Nucleic Acids Res. 11:1567-1577(1983) Girgis K.R., Capra D.J., Stroynowski I. Nucleotide sequences of three H-2K and three H-2D complementary DNA clones coding mouse class I MHC heavy chain proteins.Wang M., Stepkowski S.M., Hebert J.S., Tian L., Yu J., Kahan B.D.Ann. Transplant. 1:26-31(1996) Amino acid sequence of residues 1-98 of the K-2Kb murine major histocompatibility alloantigen comparison with H-2Kb and H-2db reveals extensive localized differences.Kimball E.S., Nathenson S.G., Coligan J.E.Biochemistry 20:3301-3308(1981) Oligosaccharide microheterogeneity of the murine major histocompatibility antigens. Reproducible site-specific patterns of sialylation and branching in asparagine-linked oligosaccharides.Swiedler S.J., Freed J.H., Tarentino A.L., Plummer T.H. Jr., Hart G.W.J. Biol. Chem. 260:4046-4054(1985) Large-scale phosphorylation analysis of mouse liver.Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007) The phagosomal proteome in interferon-gamma-activated macrophages.Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.Immunity 30:143-154(2009)
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 Research Articles on H2-K1    1. Major histocompatibility class I molecules H2-Kb and H2-Db proteins regulate sculpting of local cortical circuits and in their absence, the excess connectivity can function as a substrate for cortical plasticity throughout life.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with H2-K1 recombinant protein
 Products by Pathway  Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
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