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HA1 recombinant protein :: HA1 (H11N2) (A/duck/Yangzhou/906/2002) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS434013
Testing Data
Unit / Price
0.05 mg  /  $350 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HA1 (H11N2) (A/duck/Yangzhou/906/2002), Recombinant Protein

 Also Known As   

HA1 (H11N2) (aa 17-342) (A/duck/Yangzhou/906/2002)

 Product Synonym Names    HA1 (H11N2) (A/duck/Yangzhou/906/2002); glycosylated recombinant protein; HA1 (aa 17-342)(H11N2)(A/duck/Yangzhou/906/2002); HA1 (H11N2), 6xHis tagged Hemagglutinin (A/duck/Yangzhou/906/2002) (aa 17-342), glycosylated recombinant protein
 Product Gene Name   

HA1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Host    293 cell culture
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 Purity/Purification    > 95% (SDS-PAGE)
 Concentration    1 mug/mul in PBS. (lot specific)
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 Viral Protein    C-terminal 6xHis tagged HA1 (H11N2)(A/duck/Yangzhou/906/2002) protein (amino acid 17-342) (Genebank No. ABI47995).
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 Preparation and Storage    Store at -20 degree C. Stable for 6-months from the date of shipment when kept at 4 degree C. Non-hazardous. No MSDS required.
 Other Notes    Small volumes of HA1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for HA1 recombinant protein

   Description: 6xHis tagged Hemagglutinin (amino acid 17-342) (H11N2) (A/duck/Yangzhou/906/2002) (Genebank No. AAY85533)
Viral protein purified from 293 cell culture.
Introduction: Influenza hemagglutinin (HA) is a type of hemagglutinin found on the surface of the influenza viruses. HA is an antigenic glycoprotein, like all other hemagglutinins, it causes red blood cells to agglutinate. HA is responsible for binding the virus to the cell that is being infected. HA proteins bind to cells with sialic acid on the membranes, such as cells in the upper respiratory tract or erythrocytes.
HA is a homotrimeric integral membrane glycoprotein. HA monomer is synthesized as a single polypeptide that is subsequently cleaved into two smaller polypeptides, the HA1 and HA2 subunits. Each HA monomer consists of a long, helical chain anchored in the membrane by HA2 and topped by a large HA1 globule.
 Product Categories/Family for HA1 recombinant protein    Viral Recombinant Proteins; Influenza
 Applications Tested/Suitable for HA1 recombinant protein   

Western Blot (WB), ELISA (EIA)

 Application Notes for HA1 recombinant protein    SDS-PAGE Data: purified HA1 (H11N2)(A/duck/Yangzhou/906/2002) protein.
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 Testing Data of HA1 recombinant protein    HA1 recombinant protein Testing Data image
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NCBI/Uniprot data below describe general gene information for HA1. It may not necessarily be applicable to this product.
 NCBI GI #    68137154
 NCBI Accession #    AAY85533.1 [Other Products]
 Molecular Weight    63,021 Da
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 NCBI Official Full Name    hemagglutinin
 UniProt Protein Name    Hemagglutinin
 UniProt Gene Name    HA [Similar Products]
 UniProt Entry Name    Q4JJG4_9INFA
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 UniProt Comments for HA1    Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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