Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow HBA2  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Relaxin (RLN) ELISA Kit
 • Katacalcin Peptide
 • GNA15 Antibody
 • F11 - FXI - Factor XI Antibody
 • MIA (Melanoma inhibitory activity) Recombinant Protein
 • Total Immunoglobulin (TIG) ELISA Kit
 • NGAL Recombinant Protein
 • COL1A1 Antibody
 • CHD3 ELISA Kit
 • 1,4-Sorbitan Chemical Reference
 • EPHA5 Antibody
 • Lamin A Antibody
 • ATP-sensitive inward rectifier potassium channel 10 (KCNJ10) Antibody
 • b2-Microglobulin (HLA-G) Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

HBA2 recombinant protein

Scan QR to view Datasheet Catalog #    MBS204421
SDS-Page
Unit / Price
0.1 mg  /  $310 +1 FREE 8GB USB
0.5 mg  /  $720 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HBA2, Recombinant Protein

★Popular Item★
 Also Known As   

HBA2, 1-142aa, Human, His tag, E Coli (Denatured)

 Product Synonym Names    Hemoglobin subunit alpha; nucleophosmin/nucleoplasmin 2
 Product Gene Name   

HBA2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence    MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMVL SPADKTNVKA AWGKVGAHAG EYGAEALERM FLSFPTTKTY FPHFDLSHGS AQVKGHGKKV ADALTNAVAH VDDMPNALSA LSDLHAHKLR VDPVNFKLLS HCLLVTLAAH LPAEFTPAVH ASLDKFLASV STVLTSKYR
 OMIM    J00153 Genomic DNA
 3D Structure    ModBase 3D Structure for P69905
Section Bar
 Host    E Coli
Section Bar
 Purity/Purification    > 90% by SDS-PAGE
 Form/Format    Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 2M urea, 2mM DTT
 Concentration    1 mg/ml (determined by Bradford assay) (lot specific)
Section Bar
 Antigen Species    Human
 Tag Information    His-tag
Section Bar
 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of HBA2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for HBA2 recombinant protein

   Hemoglobin subunit alpha, also known as HBA2, belongs to the globin family. HBA2 is involved in oxygen transport from the lung to the various peripheral tissues. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. Recombinant human HBA2 protein, fused to His-tag at N-terminus, was expressed in E Coli.
 Product Categories/Family for HBA2 recombinant protein    Cardiovascular
 Applications Tested/Suitable for HBA2 recombinant protein   

SDS-PAGE

Section Bar
 SDS-Page of HBA2 recombinant protein    HBA2 recombinant protein SDS-Page image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for HBA2. It may not necessarily be applicable to this product.
 NCBI GI #    4504345
 NCBI GeneID    3040
 NCBI Accession #    NP_000508 [Other Products]
 NCBI GenBank Nucleotide #    NM_000517.4 [Other Products]
Section Bar
 UniProt Primary Accession #    P69905 [Other Products]
 UniProt Secondary Accession #    P01922; Q1HDT5; Q3MIF5; Q53F97; Q96KF1; Q9NYR7; Q9UCM0 [Other Products]
 UniProt Related Accession #    P69905 [Other Products]
 Molecular Weight    19.5 kDa (179aa)
Table BarTOPTable Bar
 NCBI Official Full Name    hemoglobin subunit alpha
 NCBI Official Synonym Full Names    hemoglobin subunit alpha 2
 NCBI Official Symbol    HBA2 [Similar Products]
 NCBI Official Synonym Symbols   
HBH; HBA-T2
[Similar Products]
 NCBI Protein Information    hemoglobin subunit alpha
 UniProt Protein Name    Hemoglobin subunit alpha
 UniProt Synonym Protein Names   
Alpha-globin; Hemoglobin alpha chain
 UniProt Gene Name    HBA1 [Similar Products]
Section Bar
 NCBI Summary for HBA2    The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for HBA2    Involved in oxygen transport from the lung to the various peripheral tissues.
Table BarTOPTable Bar
 

Product References and Citations for HBA2 recombinant protein

   Jorge S.B., et al. (2003) Braz. J. Med. Biol. Res. 36:1471-1474; Abdulmalik O., et al. (2004) Am. J. Hematol. 77:268-276
Section Bar
 Research Articles on HBA2    1. In this paper, the experimental results of resonance Raman, terahertz time-domain, and 1H nuclear magnetic resonance spectroscopy for the Hb M are described in detail. The heterogeneity of alpha subunits, which has been observed previously, is reconfirmed, and its implications for the dynamical structure of the alpha2beta2 tetramer and the regulation of O2 affinity are discussed.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with HBA2 recombinant proteinPathways associated with HBA2 recombinant protein
 Reference Product  PubMed Publications
 HBA1 recombinant protein  >94 publications with HBA2 and HBA1
 HBB recombinant protein  >47 publications with HBA2 and HBB
 HBD recombinant protein  >34 publications with HBA2 and HBD
 HBG2 recombinant protein  >6 publications with HBA2 and HBG2
 HBG1 recombinant protein  >4 publications with HBA2 and HBG1
 HBE1 recombinant protein  >1 publications with HBA2 and HBE1
 AHSP recombinant protein  >1 publications with HBA2 and AHSP
 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Erythrocytes Take Up Carbon Dioxide And Release Oxygen Pathway antibodies  Erythrocytes Take Up Carbon Dioxide And Release Oxygen Pathway Diagram
 Erythrocytes Take Up Oxygen And Release Carbon Dioxide Pathway antibodies  Erythrocytes Take Up Oxygen And Release Carbon Dioxide Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 O2/CO2 Exchange In Erythrocytes Pathway antibodies  O2/CO2 Exchange In Erythrocytes Pathway Diagram
 Scavenging Of Heme From Plasma Pathway antibodies  Scavenging Of Heme From Plasma Pathway Diagram
Diseases associated with HBA2 recombinant proteinOrgans/Tissues associated with HBA2 recombinant protein
 Disease Name  Pubmed Publications
 Anemia Antibodies  >457 publications with HBA2 and Anemia
 alpha-Thalassemia Antibodies  >246 publications with HBA2 and alpha-Thalassemia
 Kidney Diseases Antibodies  >8 publications with HBA2 and Kidney Diseases
 Carcinoma Antibodies  >7 publications with HBA2 and Carcinoma
 Hyperplasia Antibodies  >6 publications with HBA2 and Hyperplasia
 Inflammation Antibodies  >5 publications with HBA2 and Inflammation
 Necrosis Antibodies  >5 publications with HBA2 and Necrosis
 Heart Diseases Antibodies  >5 publications with HBA2 and Heart Diseases
 Edema Antibodies  >5 publications with HBA2 and Edema
 Polycythemia Antibodies  >4 publications with HBA2 and Polycythemia
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >389 publications with HBA2 and Blood
 Bone Antibodies  >21 publications with HBA2 and Bone
 Bone Marrow Antibodies  >13 publications with HBA2 and Bone Marrow
 Liver Antibodies  >12 publications with HBA2 and Liver
 Eye Antibodies  >10 publications with HBA2 and Eye
 Heart Antibodies  >8 publications with HBA2 and Heart
 Kidney Antibodies  >8 publications with HBA2 and Kidney
 Spleen Antibodies  >6 publications with HBA2 and Spleen
 Brain Antibodies  >5 publications with HBA2 and Brain
 Skin Antibodies  >4 publications with HBA2 and Skin
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions