NP_001156752.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
85,853 Da
NCBI Official Full Name
HIV Tat-specific factor 1
NCBI Official Synonym Full Names
HIV-1 Tat specific factor 1
NCBI Protein Information
HIV Tat-specific factor 1
UniProt Protein Name
HIV Tat-specific factor 1
UniProt Synonym Gene Names
NCBI Summary for HTATSF1
The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Sep 2009]
UniProt Comments for HTATSF1
Functions as a general transcription factor playing a role in the process of transcriptional elongation. May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation. In case of infection by HIV-1, it is up-regulated by the HIV-1 proteins NEF and gp120, acts as a cofactor required for the Tat-enhanced transcription of the virus.
Research Articles on HTATSF1
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Products associated with HTATSF1 recombinant protein
Diseases associated with HTATSF1 recombinant protein
Organs/Tissues associated with HTATSF1 recombinant protein
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