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DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

HLA-DMA recombinant protein

Scan QR to view Datasheet Catalog #    MBS1258275
SDS-Page
Unit / Price
0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HLA-DMA, Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human HLA-DMA protein

 Product Synonym Names    Homo sapiens (Human)
 Product Gene Name   

HLA-DMA recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS1258275 COA    COA PDF
 Sequence Positions    27-233aa; Partial
 Sequence    VPEAPTPMWP DDLQNHTFLH TVYCQDGSPS VGLSEAYDED QLFFFDFSQN TRVPRLPEFA DWAQEQGDAP AILFDKEFCE WMIQQIGPKL DGKIPVSRGF PIAEVFTLKP LEFGKPNTLV CFVSNLFPPM LTVNWQHHSV PVEGFGPTFV SAVDGLSFQA FSYLNFTPEP SDIFSCIVTH EIDRYTAIAY WVPRNALPSD LLENVLC
 3D Structure    ModBase 3D Structure for Q6ICR9
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of HLA-DMA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for HLA-DMA recombinant protein    Cardiovascular
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 SDS-Page of HLA-DMA recombinant protein    HLA-DMA recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for HLA-DMA. It may not necessarily be applicable to this product.
 NCBI GI #    18765715
 NCBI GeneID    3108
 NCBI Accession #    NP_006111.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_006120.3 [Other Products]
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 UniProt Primary Accession #    Q6ICR9 [Other Products]
 UniProt Related Accession #    P28067 [Other Products]
 Molecular Weight    27.5kD
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 NCBI Official Full Name    HLA class II histocompatibility antigen, DM alpha chain
 NCBI Official Synonym Full Names    major histocompatibility complex, class II, DM alpha
 NCBI Official Symbol    HLA-DMA [Similar Products]
 NCBI Official Synonym Symbols   
DMA; HLADM; RING6; D6S222E
[Similar Products]
 NCBI Protein Information    HLA class II histocompatibility antigen, DM alpha chain
 UniProt Protein Name    HLA-DMA protein
 UniProt Synonym Protein Names   
HLA-DMA protein
 Protein Family    HLA class II histocompatibility antigen
 UniProt Gene Name    HLA-DMA [Similar Products]
 UniProt Entry Name    Q6ICR9_HUMAN
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 NCBI Summary for HLA-DMA    HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq, Jul 2008]
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Product References and Citations for HLA-DMA recombinant protein

   "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)." Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B. Submitted (MAY-2004)
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 Research Articles on HLA-DMA    1. study therefore reveals that HLA-DM polymorphic residues have a considerable impact on HLA-DM catalytic activity.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HLA-DMA recombinant proteinPathways associated with HLA-DMA recombinant protein
 Reference Product  PubMed Publications
 HLA-DMB recombinant protein  >350 publications with HLA-DMA and HLA-DMB
 HLA-DRB1 recombinant protein  >34 publications with HLA-DMA and HLA-DRB1
 HLA-DRA recombinant protein  >18 publications with HLA-DMA and HLA-DRA
 CD74 recombinant protein  >6 publications with HLA-DMA and CD74
 CD82 recombinant protein  >4 publications with HLA-DMA and CD82
 HLA-DOA recombinant protein  >4 publications with HLA-DMA and HLA-DOA
 HLA-DOB recombinant protein  >2 publications with HLA-DMA and HLA-DOB
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
Diseases associated with HLA-DMA recombinant proteinOrgans/Tissues associated with HLA-DMA recombinant protein
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >56 publications with HLA-DMA and Immune System Diseases
 Diabetes Mellitus Antibodies  >9 publications with HLA-DMA and Diabetes Mellitus
 Gastrointestinal Diseases Antibodies  >7 publications with HLA-DMA and Gastrointestinal Diseases
 Inflammation Antibodies  >6 publications with HLA-DMA and Inflammation
 Necrosis Antibodies  >4 publications with HLA-DMA and Necrosis
 Liver Diseases Antibodies  >4 publications with HLA-DMA and Liver Diseases
 Poisoning Antibodies  >2 publications with HLA-DMA and Poisoning
 Ovarian Neoplasms Antibodies  >2 publications with HLA-DMA and Ovarian Neoplasms
 Respiratory Tract Diseases Antibodies  >2 publications with HLA-DMA and Respiratory Tract Diseases
 Lung Diseases Antibodies  >2 publications with HLA-DMA and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >133 publications with HLA-DMA and Blood
 Kidney Antibodies  >9 publications with HLA-DMA and Kidney
 Bone Antibodies  >9 publications with HLA-DMA and Bone
 Bone Marrow Antibodies  >8 publications with HLA-DMA and Bone Marrow
 Thymus Antibodies  >7 publications with HLA-DMA and Thymus
 Lymph Node Antibodies  >6 publications with HLA-DMA and Lymph Node
 Lymph Antibodies  >4 publications with HLA-DMA and Lymph
 Intestine Antibodies  >4 publications with HLA-DMA and Intestine
 Thyroid Antibodies  >4 publications with HLA-DMA and Thyroid
 Tonsil Antibodies  >4 publications with HLA-DMA and Tonsil
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