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Product Name
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Hepatitis B Surface Antigen HBsAg adw, Recombinant Protein
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Also Known As
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Hepatitis B Surface Antigen HBsAg adw, Recombinant, Human
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Research Use Only
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For Research Use Only. Not for use in diagnostic procedures.
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Host
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Saccharomyces cerevisae
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Purity/Purification
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Highly Purified ~95%. SDS-PAGE Purified from broken yeast cells by clarification, ultrafiltration, adsorption chromatography, ion-exchange chromatography, ultracentrifugation, CsCl Centrifugation, gel filtration, sterile filtration.
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Form/Format
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Supplied as a liquid in 0.9% sodium chloride, 20mM TrisCl, pH 7.5.
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Preparation and Storage
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May be stored at 4 degree C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 6 months.
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Other Notes
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Small volumes of Hepatitis B Surface Antigen HBsAg adw recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Hepatitis B is an infection of the liver caused by the hepatitis B virus. Approximately 5-10% of adults and 90% of babies who are infected with HBV will go on to carry the virus for the rest of their lives. These people will pass the virus onto others. HBV is excreted in body fluids such as semen, saliva, blood and urine in persons with acute or chronic infection. The route of transmission can include homosexual or heterosexual activity, blood-borne exposure (needles, transfusion), mother-infant, close personal contact and even by consuming contaminated food or water. Thus, Hepatitis B has become a major public health concern. When HBV invades the body it causes liver damage through induction of auto-immunity. Liver cell injury results from cytotoxic T cell activity rather than viral cytotoxic activity. The principal screening test for detecting current (acute or chronic) HBV infection is the identification of HBsAg, an envelope lipoprotein. This is the first immunological marker to appear in a patient's serum and exist in high quantities in the blood. Patients who are HBsAg positive develop chronic persistent hepatitis (CPH) and chronic active hepatitis (CAH). Patients with CPH usually remain in good health. Those with CAH have progressive liver damage with the outcome being portal fibrosis, cirrhosis, or hepatocellular carcinoma. Screening for HBsAg is recommended for all donors, pregnant women and those individuals who at high risk. Presence of this marker is conclusive proof of HBV infection. This immunoassay measures HBsAg through antigen-antibody interactions.
Strain producer of yeast Saccharomyces cerevisae, containing the plasmid that carries the S gene subtype "adw".
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Product Categories/Family for Hepatitis B Surface Antigen HBsAg adw recombinant protein
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Molecular Biology; MB-Infectious Disease
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Applications Tested/Suitable for Hepatitis B Surface Antigen HBsAg adw recombinant protein
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ELISA (EL/EIA)
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Application Notes for Hepatitis B Surface Antigen HBsAg adw recombinant protein
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Suitable for used in ELISA and other immunological assays.
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NCBI/Uniprot data below describe general gene information for Hepatitis B Surface Antigen HBsAg adw. It may not necessarily be applicable to this product. |
NCBI GI #
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1567470
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NCBI Accession #
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CAA02107.1
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[Other Products]
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Molecular Weight
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2 million Daltons; morphologically, HBsAg possesses a subunit diameter of 18-22nm.
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[Similar Products]
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NCBI Official Full Name
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HBsAg adw Pre-S1 sequence
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Precautions
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All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
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Disclaimer
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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