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HGF-A recombinant protein :: Hepatocyte Growth Factor-A (HGF-A) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS343198
Unit / Price
0.01 mg  /  $225 +1 FREE 8GB USB
0.1 mg  /  $590 +1 FREE 8GB USB
1 mg  /  $2,685 +3 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Hepatocyte Growth Factor-A (HGF-A), Recombinant Protein

★Popular Item★
 Also Known As   

Hepatocyte Growth Factor-A (HGF-A)

 Product Synonym Names    Scatter Factor; Lung Fibroblast-Derived Mitogen, Hepatopoietin A; Hepatocyte Growth Factor-A
 Product Gene Name   

HGF-A recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    604552
 3D Structure    ModBase 3D Structure for Q04756
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 Purity/Purification    >95%
 Form/Format    Liquid
 Concentration    0.75 mg/ml (lot specific)
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 Total Volume    1.34 ml
 Total Protein    1000 ug
 Buffer    25mM Na. Acetate pH 4.8, 1mM EDTA 50% Glycerol.
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 Preparation and Storage    Store at -20C
 ISO Certification    Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
 Other Notes    Small volumes of HGF-A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for HGF-A recombinant protein

   Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase-signalling cascade. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. Recombinant HGF-A comprises a 463 amino acid fragment (32-494) corresponding to the mature HGF-A protein and is expressed in E Coli with an amino-terminal hexahistidine tag. This product is not intended for therapeutic use.
 Product Categories/Family for HGF-A recombinant protein    Recombinant Proteins; Hepatocyte Growth Factor A (HGF-A)
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 SDS-PAGE of HGF-A recombinant protein    HGF-A recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for HGF-A. It may not necessarily be applicable to this product.
 NCBI GI #    4504383
 NCBI GeneID    3083
 NCBI Accession #    NP_001519.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001528.3 [Other Products]
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 UniProt Primary Accession #    Q04756 [Other Products]
 UniProt Secondary Accession #    Q14726; Q2M1W7; Q53X47 [Other Products]
 UniProt Related Accession #    Q04756 [Other Products]
 Molecular Weight    57.8kDa
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 NCBI Official Full Name    hepatocyte growth factor activator isoform 2 preproprotein
 NCBI Official Synonym Full Names    HGF activator
 NCBI Official Symbol    HGFAC [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    hepatocyte growth factor activator
 UniProt Protein Name    Hepatocyte growth factor activator
 UniProt Gene Name    HGFAC [Similar Products]
 UniProt Synonym Gene Names    HGF activator; HGFA [Similar Products]
 UniProt Entry Name    HGFA_HUMAN
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 NCBI Summary for HGF-A    This gene encodes a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
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 UniProt Comments for HGF-A    HGFAC: Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form. Belongs to the peptidase S1 family.

Protein type: Secreted, signal peptide; Secreted; EC 3.4.21.-; Protease

Chromosomal Location of Human Ortholog: 4p16

Molecular Function: serine-type peptidase activity
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Product References and Citations for HGF-A recombinant protein

   Miyazawa, K. et al (1993) Journal of Biological Chemistry 268: 10024-10028. Shimomura T. et al (1992) Cytotechnology 8: 219-229.
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 Research Articles on HGF-A    1. Based upon ethnicity-stratified single-variant association analysis and trans-ethnic meta-analysis of 6201 participants of the Multi-Ethnic Study of Atherosclerosis, discovered 5 common and low-frequency variants: HGF missense polymorphism rs5745687 (p.E299K) and 4 variants (rs16844364, rs4690098, rs114303452, rs3748034) within or in proximity to HGFAC.[Meta-analysis]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with HGF-A recombinant proteinOrgans/Tissues associated with HGF-A recombinant protein
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >1 publications with HGF-A and Carcinoma
 Cardiovascular Diseases Antibodies  >1 publications with HGF-A and Cardiovascular Diseases
 Ovarian Neoplasms Antibodies  >1 publications with HGF-A and Ovarian Neoplasms
 Heart Diseases Antibodies  >1 publications with HGF-A and Heart Diseases
 Liver Diseases Antibodies  >1 publications with HGF-A and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1 publications with HGF-A and Liver
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