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Fcer1a recombinant protein :: High affinity immunoglobulin epsilon receptor subunit alpha Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS7042726
SDS-PAGE
Unit / Price
0.01 mg  /  $855 +1 FREE 8GB USB
0.05 mg  /  $1,355 +1 FREE 8GB USB
0.1 mg  /  $2,280 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

High affinity immunoglobulin epsilon receptor subunit alpha (Fcer1a), Recombinant Protein

★Popular Item★
 Also Known As   

High affinity immunoglobulin epsilon receptor subunit alpha

 Product Gene Name   

Fcer1a recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS7042726 COA    COA PDF
 Sequence Positions    24-250aa; Full Length of Mature Protein
 Sequence    ATEKSVLTLD PPWIRIFTGE KVTLSCYGNN HLQMNSTTKW IHNGTVSEVN SSHLVIVSAT VQDSGKYICQ KQGLFKSKPV YLNVTQDWLL LQTSADMVLV HGSFDIRCHG WKNWNVRKVI YYRNDHAFNY SYESPVSIRE ATLNDSGTYH CKGYLRQVKY ESDKFRIAVV KAYKCKYYWL QLIFPLLVAI LFAVDTGLLL STEEQFKSVL EIQKTGKYKK VETELLT
 3D Structure    ModBase 3D Structure for P20489
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 Host    E Coli
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE.
 Form/Format    Liquid containing glycerol
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 Species    Mus musculus (Mouse)
 Storage Buffer    Tris-based buffer, 50% glycerol.
 Tag Information    Tag type will be determined during the manufacturing process. Additional charge for tag removal. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Fcer1a recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for Fcer1a recombinant protein

   This is a recombinant transmembrane protein expressed in a cell-free expression system.
 Product Categories/Family for Fcer1a recombinant protein    Transmembrane Protein
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 SDS-PAGE of Fcer1a recombinant protein    Fcer1a recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Fcer1a. It may not necessarily be applicable to this product.
 NCBI GI #    226823365
 NCBI GeneID    14125
 NCBI Accession #    NP_034314.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_010184.2 [Other Products]
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 UniProt Primary Accession #    P20489 [Other Products]
 UniProt Secondary Accession #    E9QLR4 [Other Products]
 UniProt Related Accession #    P20489 [Other Products]
 Molecular Weight    28,657 Da
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 NCBI Official Full Name    high affinity immunoglobulin epsilon receptor subunit alpha
 NCBI Official Synonym Full Names    Fc receptor, IgE, high affinity I, alpha polypeptide
 NCBI Official Symbol    Fcer1a [Similar Products]
 NCBI Official Synonym Symbols   
FcERI; Fce1a; Fcr-5; fcepsilonri
[Similar Products]
 NCBI Protein Information    high affinity immunoglobulin epsilon receptor subunit alpha
 UniProt Protein Name    High affinity immunoglobulin epsilon receptor subunit alpha
 UniProt Synonym Protein Names   
Fc-epsilon RI-alpha; FcERI; IgE Fc receptor subunit alpha
 Protein Family    High affinity immunoglobulin epsilon receptor
 UniProt Gene Name    Fcer1a [Similar Products]
 UniProt Synonym Gene Names    Fce1a; FcERI [Similar Products]
 UniProt Entry Name    FCERA_MOUSE
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 UniProt Comments for Fcer1a    FCER1A: Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.

Protein type: Membrane protein, integral

Cellular Component: cell surface; external side of plasma membrane; integral to plasma membrane; lipid raft

Molecular Function: IgE binding; IgE receptor activity; protein binding

Biological Process: activation of JNK activity; activation of MAPK activity; cell surface receptor linked signal transduction; leukotriene biosynthetic process; positive regulation of calcium-mediated signaling; positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; positive regulation of interleukin-3 biosynthetic process; positive regulation of mast cell degranulation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of type I hypersensitivity; serotonin secretion; signal transduction
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 Research Articles on Fcer1a    1. Tim-3 acts at a receptor-proximal point to enhance Lyn kinase-dependent signaling pathways that modulate both immediate-phase degranulation and late-phase cytokine production downstream of FcepsilonRI ligation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Fcer1a recombinant proteinPathways associated with Fcer1a recombinant protein
 Reference Product  PubMed Publications
 Ms4a2 recombinant protein  >10 publications with Fcer1a and Ms4a2
 Fcer1g recombinant protein  >6 publications with Fcer1a and Fcer1g
 Syk recombinant protein  >2 publications with Fcer1a and Syk
 Ighe recombinant protein  >1 publications with Fcer1a and Ighe
 Lyn recombinant protein  >1 publications with Fcer1a and Lyn
 Products by Pathway  Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 Fc Epsilon Receptor (FCERI) Signaling Pathway antibodies  Fc Epsilon Receptor (FCERI) Signaling Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Phospholipase D Signaling Pathway antibodies  Phospholipase D Signaling Pathway Diagram
 Phospholipase D Signaling Pathway antibodies  Phospholipase D Signaling Pathway Diagram
 Sphingolipid Signaling Pathway antibodies  Sphingolipid Signaling Pathway Diagram
Diseases associated with Fcer1a recombinant proteinOrgans/Tissues associated with Fcer1a recombinant protein
 Disease Name  Pubmed Publications
 Asthma Antibodies  >23 publications with Fcer1a and Asthma
 Respiratory Tract Diseases Antibodies  >21 publications with Fcer1a and Respiratory Tract Diseases
 Respiratory Hypersensitivity Antibodies  >19 publications with Fcer1a and Respiratory Hypersensitivity
 Urticaria Antibodies  >14 publications with Fcer1a and Urticaria
 Inflammation Antibodies  >10 publications with Fcer1a and Inflammation
 Drug Hypersensitivity Antibodies  >9 publications with Fcer1a and Drug Hypersensitivity
 Necrosis Antibodies  >3 publications with Fcer1a and Necrosis
 Breast Neoplasms Antibodies  >2 publications with Fcer1a and Breast Neoplasms
 Carcinoma Antibodies  >2 publications with Fcer1a and Carcinoma
 Atherosclerosis Antibodies  >1 publications with Fcer1a and Atherosclerosis
 Organ/Tissue Name  Pubmed Publications
 Bone Marrow Antibodies  >5 publications with Fcer1a and Bone Marrow
 Spleen Antibodies  >1 publications with Fcer1a and Spleen
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