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H3F3A recombinant protein :: Histone H3.3 (H3F3A) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1456715 H3F3A recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $530 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $695 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $710 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $780 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $845 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $935 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,050 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,065 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,085 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,095 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,545 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,595 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,660 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,070 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Histone H3.3 (H3F3A), Recombinant Protein

 Also Known As   

Recombinant Bovine Histone H3.3 (H3F3A)

 Product Synonym Names    Histone H3.3
 Product Gene Name   

H3F3A recombinant protein

[Similar Products]
 Product Synonym Gene Name    H3F3A; AND; H3F3B [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    2-136aa; full length protein
 Sequence    ARTKQTARK STGGKAPRKQ LATKAARKSA PSTGGVKKPH RYRPGTVALR EIRRYQKSTE LLIRKLPFQR LVREIAQDFK TDLRFQSAAI GALQEASEAY LVGLFEDTNL CAIHAKRVTI MPKDIQLARR IRGERA
 3D Structure    ModBase 3D Structure for Q5E9F8
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Bos taurus (Bovine)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of H3F3A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for H3F3A recombinant protein

   Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family.
NCBI/Uniprot data below describe general gene information for H3F3A. It may not necessarily be applicable to this product.
 NCBI GI #    62177168
 NCBI GeneID    326601
 NCBI Accession #    NP_001014411.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001014389.2 [Other Products]
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 UniProt Primary Accession #    Q5E9F8 [Other Products]
 UniProt Secondary Accession #    Q862G6; Q862V0; Q862W6; A4IFS1 [Other Products]
 UniProt Related Accession #    Q5E9F8 [Other Products]
 Molecular Weight    15,328 Da
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 NCBI Official Full Name    histone H3.3
 NCBI Official Symbol    H3F3A [Similar Products]
 NCBI Protein Information    histone H3.3
 UniProt Protein Name    Histone H3.3
 UniProt Gene Name    H3F3A [Similar Products]
 UniProt Entry Name    H33_BOVIN
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 UniProt Comments for H3F3A    H3: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Belongs to the histone H3 family.

Protein type: DNA-binding
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with H3F3A recombinant proteinDiseases associated with H3F3A recombinant protein
 Products by Pathway  Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Amyloids Pathway antibodies  Amyloids Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cellular Senescence Pathway antibodies  Cellular Senescence Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Chromatin Modifying Enzymes Pathway antibodies  Chromatin Modifying Enzymes Pathway Diagram
 Chromatin Organization Pathway antibodies  Chromatin Organization Pathway Diagram
 Chromosome Maintenance Pathway antibodies  Chromosome Maintenance Pathway Diagram
 Disease Name  Pubmed Publications
 Glioma Antibodies  >26 publications with H3F3A and Glioma
 Glioblastoma Antibodies  >19 publications with H3F3A and Glioblastoma
 Nervous System Diseases Antibodies  >17 publications with H3F3A and Nervous System Diseases
 Central Nervous System Diseases Antibodies  >16 publications with H3F3A and Central Nervous System Diseases
 Giant Cell Tumor of Bone Antibodies  >2 publications with H3F3A and Giant Cell Tumor of Bone
 Carcinoma Antibodies  >2 publications with H3F3A and Carcinoma
 Cell Transformation, Neoplastic Antibodies  >1 publications with H3F3A and Cell Transformation, Neoplastic
 Hypertrophy Antibodies  >1 publications with H3F3A and Hypertrophy
 Prostatic Diseases Antibodies  >1 publications with H3F3A and Prostatic Diseases
 Adenocarcinoma Antibodies  >1 publications with H3F3A and Adenocarcinoma
Organs/Tissues associated with H3F3A recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >27 publications with H3F3A and Brain
 Muscle Antibodies  >1 publications with H3F3A and Muscle
 Lung Antibodies  >1 publications with H3F3A and Lung
 Kidney Antibodies  >1 publications with H3F3A and Kidney
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