NP_195526.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
56,023 Da
NCBI Official Full Name
histone deacetylase 1
NCBI Official Synonym Symbols
ARABIDOPSIS HISTONE DEACETYLASE 1; ARABIDOPSIS HISTONE DEACETYLASE 19; ATHD1; ATHDA19; ATRPD3A; F20D10.250; F20D10_250; HDA1; HDA19; HISTONE DEACETYLASE; histone deacetylase 1; HISTONE DEACETYLASE 19; HISTONE DEACETYLASE19; RPD3A [Similar Products]
NCBI Protein Information
histone deacetylase 1
UniProt Protein Name
Histone deacetylase 19
UniProt Synonym Gene Names
NCBI Summary for HDA19
Encodes a histone deacetylase that enhances AtERF7-mediated transcriptional repression. Binds SIM3 and ERF7. Expressed in the nucleus in most tissues examined and throughout the life of the plant. Involved in jasmonic acid and ethylene dependent pathogen resistance. The sequence in GenBank has 17 AG dinucleotide repeats missing, which is also missing in Ler shotgun sequence from Cereon. Although it is annotated to be in Columbia, the GB sequence is probably not of Columbia origin. Plays a role in embryogenesis as mutants grown at higher temperatures display abnormalities in the organization of the root and shoot. Plant lines expressing an RNAi construct targeted against HDA19 shows some resistance to agrobacterium-mediated root transformation.
UniProt Comments for HDA19
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDA19 is involved in jasmonic acid and ethylene signaling of pathogen response. Part of a repressor complex including APETALA2 (AP2) and TOPLESS (TPL) that control the expression domains of numerous floral organ identity genes (PubMed:23034631).
Research Articles on HDA19
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Pathways associated with HDA19 recombinant protein
Organs/Tissues associated with HDA19 recombinant protein
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