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Sap30 recombinant protein :: Histone deacetylase complex subunit SAP30 (Sap30) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1003997 Sap30 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $970 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $970 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,195 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,195 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,460 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,460 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,925 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,925 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Histone deacetylase complex subunit SAP30 (Sap30), Recombinant Protein

 Also Known As   

Recombinant Mouse Histone deacetylase complex subunit SAP30 (Sap30)

 Product Synonym Names    Histone deacetylase complex subunit SAP30; 30 kDa Sin3-associated polypeptide; Sin3 corepressor complex subunit SAP30; Sin3-associated polypeptide p30
 Product Gene Name   

Sap30 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-220
 Sequence    MNGFTPEEMS RGGDAAAAVA AVVAAAAAAA SAGNGNAAGG GAEVPGAGAV SASGPPGAAG PGPGQLCCLR EDGERCGRAA GNASFSKRIQ KSISQKKVKI ELDKSARHLY ICDYHKNLIQ SVRNRRKRKG SDDDGGDSPV QDIDTPEVDL YQLQVNTLRR YKRHFKLPTR PGLNKAQLVE IVGCHFKSIP VNEKDTLTCF IYSVRNDKNK SDLKADSGVH
 3D Structure    ModBase 3D Structure for O88574
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Sap30 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for Sap30 recombinant protein

   Sap30
NCBI/Uniprot data below describe general gene information for Sap30. It may not necessarily be applicable to this product.
 NCBI GI #    12408290
 NCBI GeneID    60406
 NCBI Accession #    NP_068560.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_021788.2 [Other Products]
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 UniProt Primary Accession #    O88574 [Other Products]
 UniProt Secondary Accession #    Q99JB9; A2RSE9 [Other Products]
 UniProt Related Accession #    O88574 [Other Products]
 Molecular Weight    23,231 Da
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 NCBI Official Full Name    histone deacetylase complex subunit SAP30
 NCBI Official Synonym Full Names    sin3 associated polypeptide
 NCBI Official Symbol    Sap30 [Similar Products]
 NCBI Official Synonym Symbols   
30kDa
[Similar Products]
 NCBI Protein Information    histone deacetylase complex subunit SAP30; Sin3-associated protein; sin3-associated polypeptide p30; sin3 associated polypeptide, 30kD; 30 kDa Sin3-associated polypeptide; sin3-associated polypeptide, 30 kDa; sin3 corepressor complex subunit SAP30
 UniProt Protein Name    Histone deacetylase complex subunit SAP30
 UniProt Synonym Protein Names   
30 kDa Sin3-associated polypeptide; Sin3 corepressor complex subunit SAP30; Sin3-associated polypeptide p30
 Protein Family    Histone deacetylase complex
 UniProt Gene Name    Sap30 [Similar Products]
 UniProt Entry Name    SAP30_MOUSE
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 UniProt Comments for Sap30    SAP30: Involved in the functional recruitment of the Sin3- histone deacetylase complex (HDAC) to a specific subset of N-CoR corepressor complexes. Capable of transcription repression by N- CoR. Active in deacetylating core histone octamers (when in a complex) but inactive in deacetylating nucleosomal histones. Belongs to the SAP30 family.

Protein type: Nuclear receptor co-regulator

Cellular Component: Sin3 complex; histone deacetylase complex; nucleus

Molecular Function: protein binding; DNA binding; metal ion binding; transcription corepressor activity

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter
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 Research Articles on Sap30    1. show using NMR that the mSin3A PAH3-SAP30 SID complex can bind to nucleic acids, hinting at a role for a nucleolar localization sequence in the SID alphaA helix in targeting the Rpd3L/Sin3L complex for silencing ribosomal RNA genes
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Sap30 recombinant proteinPathways associated with Sap30 recombinant protein
 Reference Product  PubMed Publications
 Hdac1 recombinant protein  >10 publications with Sap30 and Hdac1
 Sin3a recombinant protein  >8 publications with Sap30 and Sin3a
 Hdac2 recombinant protein  >6 publications with Sap30 and Hdac2
 Sap18 recombinant protein  >4 publications with Sap30 and Sap18
 Rbbp7 recombinant protein  >1 publications with Sap30 and Rbbp7
 Rbbp4 recombinant protein  >1 publications with Sap30 and Rbbp4
 Products by Pathway  Pathway Diagram
 Chromatin Modifying Enzymes Pathway antibodies  Chromatin Modifying Enzymes Pathway Diagram
 Chromatin Organization Pathway antibodies  Chromatin Organization Pathway Diagram
 Delta-Notch Signaling Pathway antibodies  Delta-Notch Signaling Pathway Diagram
 Epigenetic Regulation Of Gene Expression Pathway antibodies  Epigenetic Regulation Of Gene Expression Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 HDACs Deacetylate Histones Pathway antibodies  HDACs Deacetylate Histones Pathway Diagram
 Mus Musculus Biological Processes Pathway antibodies  Mus Musculus Biological Processes Pathway Diagram
 Negative Epigenetic Regulation Of RRNA Expression Pathway antibodies  Negative Epigenetic Regulation Of RRNA Expression Pathway Diagram
 NoRC Negatively Regulates RRNA Expression Pathway antibodies  NoRC Negatively Regulates RRNA Expression Pathway Diagram
 NoRC Negatively Regulates RRNA Expression Pathway antibodies  NoRC Negatively Regulates RRNA Expression Pathway Diagram
Diseases associated with Sap30 recombinant proteinOrgans/Tissues associated with Sap30 recombinant protein
 Disease Name  Pubmed Publications
 Skin Neoplasms Antibodies  >3 publications with Sap30 and Skin Neoplasms
 Fever Antibodies  >3 publications with Sap30 and Fever
 Carcinoma, Squamous Cell Antibodies  >2 publications with Sap30 and Carcinoma, Squamous Cell
 Cardiovascular Diseases Antibodies  >1 publications with Sap30 and Cardiovascular Diseases
 Necrosis Antibodies  >1 publications with Sap30 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >3 publications with Sap30 and Skin
 Brain Antibodies  >3 publications with Sap30 and Brain
 Blood Antibodies  >3 publications with Sap30 and Blood
 Embryonic Tissue Antibodies  >2 publications with Sap30 and Embryonic Tissue
 Kidney Antibodies  >1 publications with Sap30 and Kidney
 Thyroid Antibodies  >1 publications with Sap30 and Thyroid
 Mammary Gland Antibodies  >1 publications with Sap30 and Mammary Gland
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