NP_002439.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
31,496 Da
NCBI Official Full Name
homeobox protein MSX-1
NCBI Official Synonym Full Names
msh homeobox 1
NCBI Protein Information
homeobox protein MSX-1
UniProt Protein Name
Homeobox protein MSX-1
UniProt Synonym Protein Names
Homeobox protein Hox-7; Msh homeobox 1-like protein
UniProt Synonym Gene Names
NCBI Summary for MSX1
This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in this gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia. [provided by RefSeq, Jul 2008]
UniProt Comments for MSX1
Acts as a transcriptional repressor. May play a role in limb-pattern formation. Acts in cranofacial development and specifically in odontogenesis. Expression in the developing nail bed mesenchyme is important for nail plate thickness and integrity.
Research Articles on MSX1
Precautions
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Products associated with MSX1 recombinant protein
Pathways associated with MSX1 recombinant protein
Diseases associated with MSX1 recombinant protein
Organs/Tissues associated with MSX1 recombinant protein
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