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HGD recombinant protein :: Homogentisate 1,2-dioxygenase (HGD) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1354582
SDS-Page
Unit / Price
0.05 mg (E-Coli)  /  $860 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,085 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,155 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,275 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,290 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,330 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,375 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,455 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,810 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,975 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,015 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,215 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,600 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Homogentisate 1,2-dioxygenase (HGD), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Homogentisate 1,2-dioxygenase (HGD)

 Product Gene Name   

HGD recombinant protein

[Similar Products]
 Product Synonym Gene Name    HGD [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS1354582 COA    COA PDF
 Sequence Positions    1-445aa, Full Length
 Sequence    MAELKYISGF GNECSSEDPR CPGSLPEGQN NPQVCPYNLY AEQLSGSAFT CPRSTNKRSW LYRILPSVSH KPFESIDEGQ VTHNWDEVDP DPNQLRWKPF EIPKASQKKV DFVSGLHTLC GAGDIKSNNG LAIHIFLCNT SMENRCFYNS DGDFLIVPQK GNLLIYTEFG KMLVQPNEIC VIQRGMRFSI DVFEETRGYI LEVYGVHFEL PDLGPIGANG LANPRDFLIP IAWYEDRQVP GGYTVINKYQ GKLFAAKQDV SPFNVVAWHG NYTPYKYNLK NFMVINSVAF DHADPSIFTV LTAKSVRPGV AIADFVIFPP RWGVADKTFR PPYYHRNCMS EFMGLIRGHY EAKQGGFLPG GGSLHSTMTP HGPDADCFEK ASKVKLAPER IADGTMAFMF ESSLSLAVTK WGLKASRCLD ENYHKCWEPL KSHFTPNSRN PAEPN
 OMIM    203500
 3D Structure    ModBase 3D Structure for Q93099
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 85% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of HGD recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for HGD recombinant protein    Metabolism
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 SDS-Page of HGD recombinant protein    HGD recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for HGD. It may not necessarily be applicable to this product.
 NCBI GI #    115527117
 NCBI GeneID    3081
 NCBI Accession #    NP_000178.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000187.3 [Other Products]
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 UniProt Primary Accession #    Q93099 [Other Products]
 UniProt Secondary Accession #    A8K417; B2R8Z0 [Other Products]
 UniProt Related Accession #    Q93099 [Other Products]
 Molecular Weight    54.0 kDa
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 NCBI Official Full Name    homogentisate 1,2-dioxygenase
 NCBI Official Synonym Full Names    homogentisate 1,2-dioxygenase
 NCBI Official Symbol    HGD [Similar Products]
 NCBI Official Synonym Symbols   
AKU; HGO
[Similar Products]
 NCBI Protein Information    homogentisate 1,2-dioxygenase
 UniProt Protein Name    Homogentisate 1,2-dioxygenase
 UniProt Synonym Protein Names   
Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase
 Protein Family    2-(hydroxymethyl)glutarate dehydrogenase
 UniProt Gene Name    HGD [Similar Products]
 UniProt Synonym Gene Names    HGO [Similar Products]
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 NCBI Summary for HGD    This gene encodes the enzyme homogentisate 1,2 dioxygenase. This enzyme is involved in the catabolism of the amino acids tyrosine and phenylalanine. Mutations in this gene are the cause of the autosomal recessive metabolism disorder alkaptonuria.[provided by RefSeq, May 2010]
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Product References and Citations for HGD recombinant protein

   "Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011)
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 Research Articles on HGD    1. Twelve novel HGD gene variants have been identified in 99 alkaptonuria patients affecting the bones.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HGD recombinant proteinPathways associated with HGD recombinant protein
 Reference Product  PubMed Publications
 FAH recombinant protein  >5 publications with HGD and FAH
 HPD recombinant protein  >2 publications with HGD and HPD
 PAH recombinant protein  >1 publications with HGD and PAH
 Products by Pathway  Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Phenylalanine And Tyrosine Catabolism Pathway antibodies  Phenylalanine And Tyrosine Catabolism Pathway Diagram
 Tyrosine Degradation, Tyrosine => Homogentisate Pathway antibodies  Tyrosine Degradation, Tyrosine => Homogentisate Pathway Diagram
 Tyrosine Degradation, Tyrosine => Homogentisate Pathway antibodies  Tyrosine Degradation, Tyrosine => Homogentisate Pathway Diagram
 Tyrosine Metabolism Pathway antibodies  Tyrosine Metabolism Pathway Diagram
 Tyrosine Metabolism Pathway antibodies  Tyrosine Metabolism Pathway Diagram
 Tyrosine Degradation I Pathway antibodies  Tyrosine Degradation I Pathway Diagram
 Tyrosine Degradation I Pathway antibodies  Tyrosine Degradation I Pathway Diagram
Diseases associated with HGD recombinant proteinOrgans/Tissues associated with HGD recombinant protein
 Disease Name  Pubmed Publications
 Precancerous Conditions Antibodies  >178 publications with HGD and Precancerous Conditions
 Cell Transformation, Neoplastic Antibodies  >34 publications with HGD and Cell Transformation, Neoplastic
 Alkaptonuria Antibodies  >27 publications with HGD and Alkaptonuria
 Inflammation Antibodies  >24 publications with HGD and Inflammation
 Liver Neoplasms Antibodies  >11 publications with HGD and Liver Neoplasms
 Disease Models, Animal Antibodies  >9 publications with HGD and Disease Models, Animal
 Hyperplasia Antibodies  >9 publications with HGD and Hyperplasia
 Lung Neoplasms Antibodies  >7 publications with HGD and Lung Neoplasms
 Nervous System Diseases Antibodies  >6 publications with HGD and Nervous System Diseases
 Liver Diseases Antibodies  >5 publications with HGD and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >57 publications with HGD and Intestine
 Stomach Antibodies  >41 publications with HGD and Stomach
 Liver Antibodies  >28 publications with HGD and Liver
 Lymph Node Antibodies  >24 publications with HGD and Lymph Node
 Lung Antibodies  >9 publications with HGD and Lung
 Kidney Antibodies  >6 publications with HGD and Kidney
 Pancreas Antibodies  >5 publications with HGD and Pancreas
 Brain Antibodies  >5 publications with HGD and Brain
 Eye Antibodies  >3 publications with HGD and Eye
 Connective Tissue Antibodies  >3 publications with HGD and Connective Tissue
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