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Hgd recombinant protein :: Homogentisate 1,2-dioxygenase (Hgd) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1235483 Hgd recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $1,225 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,225 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,445 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,445 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,985 +2 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,985 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,450 +3 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,450 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Homogentisate 1,2-dioxygenase (Hgd), Recombinant Protein

 Also Known As   

Recombinant Mouse Homogentisate 1,2-dioxygenase (Hgd)

 Product Synonym Names    Homogentisate 1,2-dioxygenase; EC=1.13.11.5; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase
 Product Gene Name   

Hgd recombinant protein

[Similar Products]
 Product Synonym Gene Name    Hgd; Aku; Hgo [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-445
 Sequence    MAELKYISGF GNECASEDPR CPGSLPKGQN NPQVCPYNLY AEQLSGSAFT CPRNTNKRSW LYRILPSVSH KPFESIDQGH VTHNWDEVGP DPNQLRWKPF EIPKASEKKV DFVSGLYTLC GAGDIKSNNG LAVHIFLCNS SMENRCFYNS DGDFLIVPQK GKLLIYTEFG KMSLQPNEIC VIQRGMRFSV DVFEETRGYI LEVYGVHFEL PDLGPIGANG LANPRDFLIP VAWYEDRRVP GGYTVINKFQ GKLFACKQDV SPFNVVAWHG NYTPYKYNLE NFMVINAVAF DHADPSIFTV LTAKSLRPGV AIADFVIFPP RWGVADKTFR PPYYHRNCMS EFMGLIKGHY EAKQGGFLPG GGSLHSAMTP HGPDADCFEK ASKAKLEPER IADGTMAFMF ESSLSLAVTK WGLKTCSCLD ENYYKCWEPL RSHFTPNSRS PTEPK
 3D Structure    ModBase 3D Structure for O09173
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Hgd recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Hgd. It may not necessarily be applicable to this product.
 NCBI GI #    240120123
 NCBI GeneID    15233
 NCBI Accession #    NP_038575.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_013547.3 [Other Products]
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 UniProt Primary Accession #    O09173 [Other Products]
 UniProt Secondary Accession #    Q7TPP2 [Other Products]
 UniProt Related Accession #    O09173 [Other Products]
 Molecular Weight    49,960 Da
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 NCBI Official Full Name    homogentisate 1,2-dioxygenase
 NCBI Official Synonym Full Names    homogentisate 1, 2-dioxygenase
 NCBI Official Symbol    Hgd [Similar Products]
 NCBI Official Synonym Symbols   
Hgo; aku
[Similar Products]
 NCBI Protein Information    homogentisate 1,2-dioxygenase; alkaptonuria; homogentisicase; homogentisate oxygenase; homogentisic acid oxidase
 UniProt Protein Name    Homogentisate 1,2-dioxygenase
 UniProt Synonym Protein Names   
Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase
 Protein Family    2-(hydroxymethyl)glutarate dehydrogenase
 UniProt Gene Name    Hgd [Similar Products]
 UniProt Synonym Gene Names    Aku; Hgo [Similar Products]
 UniProt Entry Name    HGD_MOUSE
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 UniProt Comments for Hgd    HGD: Defects in HGD are the cause of alkaptonuria (AKU). AKU is an autosomal recessive error of metabolism characterized by an increase in the level of homogentisic acid. The clinical manifestations of AKU are urine that turns dark on standing and alkalinization, black ochronotic pigmentation of cartilage and collagenous tissues, and spine arthritis. Belongs to the homogentisate dioxygenase family.

Protein type: Amino Acid Metabolism - tyrosine; EC 1.13.11.5; Oxidoreductase

Molecular Function: homogentisate 1,2-dioxygenase activity; dioxygenase activity; metal ion binding; oxidoreductase activity

Biological Process: amino acid metabolic process; L-phenylalanine catabolic process; tyrosine catabolic process; tyrosine metabolic process
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Hgd recombinant proteinPathways associated with Hgd recombinant protein
 Reference Product  PubMed Publications
 Hpd recombinant protein  >2 publications with Hgd and Hpd
 Products by Pathway  Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Phenylalanine And Tyrosine Catabolism Pathway antibodies  Phenylalanine And Tyrosine Catabolism Pathway Diagram
 Tyrosine Degradation, Tyrosine => Homogentisate Pathway antibodies  Tyrosine Degradation, Tyrosine => Homogentisate Pathway Diagram
 Tyrosine Degradation, Tyrosine => Homogentisate Pathway antibodies  Tyrosine Degradation, Tyrosine => Homogentisate Pathway Diagram
 Tyrosine Metabolism Pathway antibodies  Tyrosine Metabolism Pathway Diagram
 Tyrosine Metabolism Pathway antibodies  Tyrosine Metabolism Pathway Diagram
 Tyrosine Degradation I Pathway antibodies  Tyrosine Degradation I Pathway Diagram
Diseases associated with Hgd recombinant proteinOrgans/Tissues associated with Hgd recombinant protein
 Disease Name  Pubmed Publications
 Precancerous Conditions Antibodies  >186 publications with Hgd and Precancerous Conditions
 Cell Transformation, Neoplastic Antibodies  >38 publications with Hgd and Cell Transformation, Neoplastic
 Alkaptonuria Antibodies  >30 publications with Hgd and Alkaptonuria
 Inflammation Antibodies  >28 publications with Hgd and Inflammation
 Liver Neoplasms Antibodies  >12 publications with Hgd and Liver Neoplasms
 Hyperplasia Antibodies  >10 publications with Hgd and Hyperplasia
 Lung Neoplasms Antibodies  >7 publications with Hgd and Lung Neoplasms
 Nervous System Diseases Antibodies  >6 publications with Hgd and Nervous System Diseases
 Liver Diseases Antibodies  >5 publications with Hgd and Liver Diseases
 Necrosis Antibodies  >5 publications with Hgd and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >15 publications with Hgd and Liver
 Lung Antibodies  >8 publications with Hgd and Lung
 Muscle Antibodies  >5 publications with Hgd and Muscle
 Kidney Antibodies  >4 publications with Hgd and Kidney
 Eye Antibodies  >3 publications with Hgd and Eye
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