Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow Hif1an  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • PLC ELISA Kit
 • IFNAR2 Antibody
 • Acetoacetic acid (ACAC) ELISA Kit
 • Ketohexokinase (Khk) ELISA Kit
 • Tissue, Genomic DNA Adult Normal, Heart, BioGenomics Genomic DNA
 • Trypsin-alpha-amylase inhibitor CMX2 Recombinant Protein
 • Angiotensin (ANG II) ELISA Kit
 • Tubulin, beta III (TUBB3) Antibody
 • Protein disulfide-isomerase precursor, PDI ELISA Kit
 • Free Fatty Acid (FFA) ELISA Kit
 • IL-1R2 ELISA Kit
 • WRB Antibody
 • TMEM115 Antibody
 • 60 kDa heat shock protein, mitochondrial (HSPD1) Recombinant Protein
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

Hif1an recombinant protein :: Hypoxia-inducible factor 1-alpha inhibitor (Hif1an) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1398467 Hif1an recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $760 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,010 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,010 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,115 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,175 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,255 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,280 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,330 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,585 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,840 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,900 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,020 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,445 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Hypoxia-inducible factor 1-alpha inhibitor (Hif1an), Recombinant Protein

 Also Known As   

Recombinant Mouse Hypoxia-inducible factor 1-alpha inhibitor (Hif1an)

 Product Gene Name   

Hif1an recombinant protein

[Similar Products]
 Product Synonym Gene Name    Hif1an [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence Positions    2-349aa, Full Length of Mature Protein
 Sequence    AATAAEVAAS GSGEAREEAE APGPAWDESQ LRSYSFPTRP IPRLSQSDPR AEELIENEEP VVLTDTNLVY PALKWDLEYL QENIGNGDFS VYSASTHKFL YYDEKKMGNF QNFKPRSNRE EIKFHEFVEK LQAIQQRGGE ERLYLQQTLN DTVGRKIVMD FLGFNWNWIN KQQGKRGWGQ LTSNLLLIGM EGNVTPAHYD EQQNFFAQIK GHKRCILFPP DQFECLYPYP VHHPCDRQSQ VDFDNPDYER FPNFRNVVGY ETVVGPGDVL YIPMYWWHHI ESLLNGGITI TVNFWYKGAP TPKRIEYPLK AHQKVAIMRN IEKMLGEALG NPQEVGPLLN TMIKGRYN
 3D Structure    ModBase 3D Structure for Q8BLR9
Section Bar
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
Section Bar
 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
Section Bar
 Species    Mouse
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
Section Bar
 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Hif1an recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for Hif1an. It may not necessarily be applicable to this product.
 NCBI GI #    70909332
 NCBI GeneID    319594
 NCBI Accession #    NP_795932.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_176958.3 [Other Products]
Section Bar
 UniProt Primary Accession #    Q8BLR9 [Other Products]
 UniProt Secondary Accession #    Q3U3G4; A1L3B7 [Other Products]
 UniProt Related Accession #    Q8BLR9 [Other Products]
 Molecular Weight    30,424 Da
Table BarTOPTable Bar
 NCBI Official Full Name    hypoxia-inducible factor 1-alpha inhibitor
 NCBI Official Synonym Full Names    hypoxia-inducible factor 1, alpha subunit inhibitor
 NCBI Official Symbol    Hif1an [Similar Products]
 NCBI Official Synonym Symbols   
FIH; FIH1; 2310046M24Rik; A830014H24Rik
[Similar Products]
 NCBI Protein Information    hypoxia-inducible factor 1-alpha inhibitor
 UniProt Protein Name    Hypoxia-inducible factor 1-alpha inhibitor
 UniProt Synonym Protein Names   
Hypoxia-inducible factor asparagine hydroxylase
 Protein Family    Hypoxia-inducible factor 1-alpha inhibitor
 UniProt Gene Name    Hif1an [Similar Products]
Section Bar
 UniProt Comments for Hif1an    Hydroxylates HIF-1 alpha at 'Asn-799' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins. Also hydroxylates Asp and His residues within ARDs of ANK1 and TNKS2, respectively. Negatively regulates NOTCH1 activity, accelerating myogenic differentiation (). Positively regulates ASB4 activity, promoting vascular differentiation.
Table BarTOPTable Bar
 Research Articles on Hif1an    1. FIH-1 has a role in disrupting the LRRK1/EGFR complex to positively regulate keratinocyte migration
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with Hif1an recombinant proteinDiseases associated with Hif1an recombinant protein
 Products by Pathway  Pathway Diagram
 Cellular Response To Hypoxia Pathway antibodies  Cellular Response To Hypoxia Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Oxygen-dependent Asparagine Hydroxylation Of Hypoxia-inducible Factor Alpha Pathway antibodies  Oxygen-dependent Asparagine Hydroxylation Of Hypoxia-inducible Factor Alpha Pathway Diagram
 PodNet: Protein-protein Interactions In The Podocyte Pathway antibodies  PodNet: Protein-protein Interactions In The Podocyte Pathway Diagram
 Regulation Of Hypoxia-inducible Factor (HIF) By Oxygen Pathway antibodies  Regulation Of Hypoxia-inducible Factor (HIF) By Oxygen Pathway Diagram
 XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway antibodies  XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >35 publications with Hif1an and Neoplasms
 Kidney Diseases Antibodies  >10 publications with Hif1an and Kidney Diseases
 Skin Diseases Antibodies  >6 publications with Hif1an and Skin Diseases
 Inflammation Antibodies  >5 publications with Hif1an and Inflammation
 Nervous System Diseases Antibodies  >5 publications with Hif1an and Nervous System Diseases
 Breast Neoplasms Antibodies  >5 publications with Hif1an and Breast Neoplasms
 Liver Diseases Antibodies  >5 publications with Hif1an and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >3 publications with Hif1an and Carcinoma, Hepatocellular
 Brain Diseases Antibodies  >3 publications with Hif1an and Brain Diseases
 Disease Models, Animal Antibodies  >2 publications with Hif1an and Disease Models, Animal
Organs/Tissues associated with Hif1an recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >15 publications with Hif1an and Kidney
 Blood Antibodies  >14 publications with Hif1an and Blood
 Liver Antibodies  >7 publications with Hif1an and Liver
 Lung Antibodies  >6 publications with Hif1an and Lung
 Brain Antibodies  >4 publications with Hif1an and Brain
 Lymph Node Antibodies  >3 publications with Hif1an and Lymph Node
 Prostate Antibodies  >3 publications with Hif1an and Prostate
 Heart Antibodies  >3 publications with Hif1an and Heart
 Muscle Antibodies  >2 publications with Hif1an and Muscle
 Bone Antibodies  >2 publications with Hif1an and Bone
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions