Q9JHH5.1
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
11,266 Da
NCBI Official Full Name
C-X-C motif chemokine 11
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 11
NCBI Official Synonym Symbols
Ip9; H174; Itac; b-R1; Cxc11; I-tac; Scyb11; Scyb9b; betaR1 [Similar Products]
NCBI Protein Information
C-X-C motif chemokine 11; small-inducible cytokine B11; interferon-inducible T-cell alpha chemoattractant; small inducible cytokine subfamily B (Cys-X-Cys), member 11
UniProt Protein Name
C-X-C motif chemokine 11
UniProt Synonym Protein Names
Interferon-inducible T-cell alpha chemoattractant; I-TAC; Small-inducible cytokine B11
UniProt Synonym Gene Names
UniProt Entry Name
CXL11_MOUSE
UniProt Comments for I-TAC
CXCL11: Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. Belongs to the intercrine alpha (chemokine CxC) family.
Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide; Chemokine
Cellular Component: extracellular space; extracellular region
Molecular Function: CXCR3 chemokine receptor binding; chemokine activity; cytokine activity
Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of leukocyte chemotaxis; immune response; response to lipopolysaccharide; chemotaxis; inflammatory response; regulation of cell proliferation
Research Articles on I-TAC
Precautions
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Disclaimer
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Pathways associated with I-TAC active protein
Diseases associated with I-TAC active protein
Organs/Tissues associated with I-TAC active protein
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