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ICAM1 recombinant protein

Scan QR to view Datasheet Catalog #    MBS539445 ICAM1 recombinant protein
Unit / Price
0.05 mg  /  $310 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ICAM1, Recombinant Protein

 Also Known As   

ICAM1 protein

 Product Synonym Names    major group rhinovirus receptor protein; ICAM1; CD54 antigen protein; ICAM 1; ICAM-1 protein; Intercellular adhesion molecule 1 protein; ICAM-1; ICAM 1 protein
 Product Gene Name   

ICAM1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    Region of ICAM1 protein correspond ing to amino acids QTSVSPSKVI LPRGGSVLVT CSTSCDQPKL LGIETPLPKK ELLLPGNNRK VYELSNVQED SQPMCYSNCP DGQSTAKTFL TVYWTPERVE LAPLPSWQPV GKNLTLRCQV EGGAPRANLT VVLLRGEKEL KREPAVGEPA EVTTTVLVRR DHHGANFSCR TELDLRPQGL ELFENTSAPY QLQTFVLPAT PPQLVSPRVL EVDTQGTVVC SLDGLFPVSE AQVHLALGDQ RLNPTVTYGN DSFSAKASVS VTAEDEGTQR LTCAVILGNQ SQETLQTVTI YSFPAPNVIL TKPEVSEGTE VTVKCEAHPR AKVTLNGVPA QPLGPRAQLL LKATPEDNGR SFSCSATLEV AGQLIHKNQT RELRVLYGPR LDERDCPGNW TWPENSQQTP MCQAWGNPLP ELKCLKDGTF PLPIGESVTV TRDLEGTYLC RARSTQGEVT RKVTVNVLSP RYE.
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 Host    Human
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 Purity/Purification    > 98% pure
 Form/Format    Supplied as a lyophilized powder.
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 Protein Type    Recombinant
 Biological Significance    ICAMs are members of the Ig superfamily of calcium-independent transmembrane glycoproteins. ICAM-1 is a ligand for lymphocyte function-associated (LFA) and Mac-1 integrins and the major human rhinovirus receptor. The primary function of ICAM-1 is to provide adhesion between endothelial cells and leukocytes after stress or injury. The human ICAM-1 gene codes for a 505 amino acid transmembrane glycoprotein containing a 29 amino acid cytoplasmic domain, a 23 amino acid transmembrane domain, and a 453 amino acid extracellular domain. Recombinant human ICAM-1 is a 49.5 kDa glycoprotein comprising the extracellular domain (453 amino acid residues) of ICAM-1.
 Bioactivity    ICAM-1 supported the adhesion of more than 50% PMA-stimulated HSB2 cells to plates coated at 25ng/ml ICAM-1 concentration
 Endotoxin Levels    Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
 Expression System    CHO cells
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 Preparation and Storage    Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of ICAM1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for ICAM1 recombinant protein

   Purified recombinant Human ICAM1 protein
 Product Categories/Family for ICAM1 recombinant protein    Immunology
 Applications Tested/Suitable for ICAM1 recombinant protein   

User optimized

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NCBI/Uniprot data below describe general gene information for ICAM1. It may not necessarily be applicable to this product.
 NCBI GI #    86561725
 NCBI GeneID    174473
 NCBI Accession #    NP_001033327.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001038238.1 [Other Products]
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 UniProt Related Accession #    Q9BLY1 [Other Products]
 Molecular Weight    72-80 kDa
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 NCBI Official Full Name    CAM-1, isoform c
 NCBI Official Symbol    cam-1 [Similar Products]
 NCBI Protein Information    CAM-1
 Protein Family    Intercellular adhesion molecule
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 Research Articles on ICAM1    1. In a Frizzled-dependent manner, PLR-1 reduces surface levels of the Wnt receptors CAM-1/Ror and LIN-18/Ryk.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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