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US12 recombinant protein :: ICP47 protein (US12) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1081523 US12 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $475 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $635 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $700 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $810 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $880 +1 FREE 8GB USB
1 mg (E-Coli)  /  $990 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $990 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,015 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,045 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,480 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,500 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,600 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $1,985 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ICP47 protein (US12), Recombinant Protein

 Also Known As   

Recombinant Human herpesvirus 2 ICP47 protein (US12)

 Product Gene Name   

US12 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-86@aa, full length protein
 Sequence    MSWALKTTDM FLDSSRCTHR TYGDVCAEIH KREREDREAA RTAVTDPELP LLCPPDVRSD PASRNPTQQT RGCARSNERQ DRVLAP
 3D Structure    ModBase 3D Structure for P14345
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2)
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of US12 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for US12. It may not necessarily be applicable to this product.
 NCBI GI #    820945225
 NCBI GeneID    1487353
 NCBI Accession #    YP_009137225.1 [Other Products]
 NCBI GenBank Nucleotide #    NC_001798.2 [Other Products]
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 UniProt Primary Accession #    P14345 [Other Products]
 UniProt Secondary Accession #    P89480 [Other Products]
 Molecular Weight    9,785 Da
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 NCBI Official Full Name    TAP transporter inhibitor ICP47
 NCBI Official Symbol    US10 [Similar Products]
 NCBI Protein Information    inhibits antigen presentation; involved in immune regulation
 UniProt Protein Name    ICP47 protein
 UniProt Synonym Protein Names   
Immediate-early protein IE12; Immediate-early-5; Infected cell protein 47; US12 protein; Vmw12
 Protein Family    ICP47 protein
 UniProt Gene Name    US12 [Similar Products]
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 UniProt Comments for US12    Plays a role in the inhibition of host immune response. Binds specifically to transporters associated with antigen processing (TAP), thereby blocking peptide-binding and translocation by TAP as well as subsequent loading of peptides onto MHC class I molecules. Empty MHC I molecules are retained in the endoplasmic reticulum and ultimately directed to proteasomal degradation. In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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