View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List IL22 active protein :: IL-22 Active Protein Catalog # MBS845284 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name IL-22 (IL22), Active Protein Popular Item Full Product Name IL-22, murine recombinant Product Synonym Names IL-TIF; TIFa; IL-10-related T-cell-derived-inducible factor; IL-22; ILTIF; IL-D110; zcyto18; MGC79382; MGC79384; TIFIL-23 Product Gene Name IL22 active protein[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP 3D Structure ModBase 3D Structure for Q9JJY9 Host E Coli Purity/Purification >=97% Form/Format Lyophilized from 1X PBS Solution Appearance: Lyophilized protein Solubility/Reconstitution Instructions Reconstitute in H?O to a concentration of 0.1 to 1.0 mg/ml. This solution can then be stored at 4 degree C for 1 week or -20 degree C for future use. For long term storage, it is recommended to add a carrier protein (e.g., 0.1% BSA). Avoid repeating freeze/thaw cycles. Endotoxin Level <0.1 ng/mug Biological Activity Recombinant murine IL-22 is fully biologically active when compared to a standard. The ED?? as determined by its ability to induce IL-10 secretion in Colo205 cells is less than 0.5 ng/ml, corresponding to a specific activity of 2 x 10 IU/mg. Results 0.5 ng/ml Handling Centrifuge the vial prior to opening. Preparation and Storage At -20 degree CShelf Life: 12 months Active Protein Note Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product. Other Notes Small volumes of IL22 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for IL22 active protein Background: Murine Interleukin-22 (IL-22), also known as T cell-derived inducible factor (ILTIF), is a cytokine that is structurally related to IL-10. Studies have shown that IL-22 induces acute-phase reactants in vitro and in vivo, suggesting that the cytokine contributes to the regulation of inflammatory responses. Recombinant murine IL-22 contains 2 x 146 amino acid chains having a total molecular mass of 33.4 kDa. Applications Tested/Suitable for IL22 active protein SDS-PAGE; HPLC TOP NCBI/Uniprot data below describe general gene information for IL22. It may not necessarily be applicable to this product. NCBI GI # 8393605 NCBI GeneID 50929 NCBI Accession # NP_058667.1 [Other Products] NCBI GenBank Nucleotide # NM_016971.2 [Other Products] UniProt Primary Accession # Q9JJY9 [Other Products] UniProt Secondary Accession # Q14BB3[Other Products] UniProt Related Accession # Q9JJY9[Other Products] Molecular Weight 33.4 kDa TOP NCBI Official Full Name interleukin-22 NCBI Official Synonym Full Names interleukin 22 NCBI Official Symbol Il22 [Similar Products] NCBI Official Synonym Symbols IL-22; Iltif; IL-22a; ILTIFa [Similar Products] NCBI Protein Information interleukin-22 UniProt Protein Name Interleukin-22 UniProt Synonym Protein Names IL-10-related T-cell-derived-inducible factor; IL-TIF; IL-TIF alpha; Interleukin-22a; IL-22a Protein Family Interleukin UniProt Gene Name Il22 [Similar Products] UniProt Synonym Gene Names Il22a; Iltif; Iltifa; IL-22; IL-TIF; IL-22a [Similar Products] UniProt Entry Name IL22_MOUSE TOP TOP UniProt Comments for IL22 IL22: Cytokine that contributes to the inflammatory response in vivo. Belongs to the IL-10 family.Protein type: Secreted, signal peptide; Cytokine; SecretedCellular Component: extracellular space; extracellular regionMolecular Function: protein binding; cytokine activityBiological Process: negative regulation of inflammatory response; regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of transcription from RNA polymerase II promoter Research Articles on IL22 1. IL-22 is a myocardium-protective cytokine by inhibiting myocardial fibrosis. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with IL22 active protein Reference Product PubMed Publications Il17a active protein >34 publications with IL22 and Il17a Stat3 active protein >13 publications with IL22 and Stat3 Il23r active protein >9 publications with IL22 and Il23r Il22ra1 active protein >5 publications with IL22 and Il22ra1 Il10ra active protein >3 publications with IL22 and Il10ra Il10rb active protein >3 publications with IL22 and Il10rb Il22ra2 active protein >3 publications with IL22 and Il22ra2 Ifngr2 active protein >2 publications with IL22 and Ifngr2 Stat1 active protein >2 publications with IL22 and Stat1 Il20rb active protein >1 publications with IL22 and Il20rb Pathways associated with IL22 active protein Products by Pathway Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Inflammatory Bowel Disease (IBD) Pathway antibodies Inflammatory Bowel Disease (IBD) Pathway Diagram Inflammatory Bowel Disease (IBD) Pathway antibodies Inflammatory Bowel Disease (IBD) Pathway Diagram Jak-STAT Signaling Pathway antibodies Jak-STAT Signaling Pathway Diagram Jak-STAT Signaling Pathway antibodies Jak-STAT Signaling Pathway Diagram Diseases associated with IL22 active protein Disease Name Pubmed Publications Inflammation Antibodies >30 publications with IL22 and Inflammation Colitis Antibodies >8 publications with IL22 and Colitis Lung Diseases Antibodies >7 publications with IL22 and Lung Diseases Death Antibodies >6 publications with IL22 and Death Necrosis Antibodies >4 publications with IL22 and Necrosis Dermatitis Antibodies >4 publications with IL22 and Dermatitis Weight Loss Antibodies >2 publications with IL22 and Weight Loss Hypersensitivity Antibodies >2 publications with IL22 and Hypersensitivity Liver Diseases Antibodies >2 publications with IL22 and Liver Diseases Fibrosis Antibodies >1 publications with IL22 and Fibrosis Organs/Tissues associated with IL22 active protein Organ/Tissue Name Pubmed Publications Brain Antibodies >4 publications with IL22 and Brain TOP © 2006-24 MyBioSource.com. 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