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IL1F10 recombinant protein :: IL-38 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS635478 IL1F10 recombinant protein
Unit / Price
0.01 mg  /  $480 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IL-38 (IL1F10), Recombinant Protein

★Popular Item★
 Also Known As   

IL-38, Recombinant, Human (His) (Interleukin-1 Family Member 10 theta, IL-1F10, FIL1 theta, FKSG75, IL-1HY2, IL1-theta, Interleukin-1 HY2, Interleukin-1 Receptor Antagonist FKSG75)

 Product Gene Name   

IL1F10 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    Human IL-38 (aa 1-152) is fused at the C-terminus to a His-tag. Swiss/UniP rot Accession: Q8WWZ1
 Chromosome Location    Chromosome: 2; NC_000002.11 (113825547..113833427). Location: 2q13
 OMIM    615296
 3D Structure    ModBase 3D Structure for Q8WWZ1
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 Purity/Purification    >95%
 Form/Format    Supplied as a lyophilized powder from 55mM Tris-Cl, pH 8.2, 150mM sodium chloride.
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 Source    E.coli
 Endotoxin    <1EU/ug protein
 Reconstitution    Reconstitute with sterile ddH2O
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 Preparation and Storage    Lyophilized powder may be stored at -20C. Stable for 12 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the orignal vial after thawing prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of IL1F10 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for IL1F10 recombinant protein

   IL-38 (IL-1F10) belongs to the IL-1 family. IL-38 is expressed in the fetal skin, spleen and tonsil, generally in the basal epithelia of skin and in proliferating B cells of the tonsil. IL-38 binds soluble IL-1 receptor type 1 and may be implicated in the regulation of adapted and innate immune responses.
 Product Categories/Family for IL1F10 recombinant protein    Growth Factors, Cytokines; Growth Factors-Interleukin
NCBI/Uniprot data below describe general gene information for IL1F10. It may not necessarily be applicable to this product.
 NCBI GI #    27894307
 NCBI GeneID    84639
 NCBI Accession #    NP_775184.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_173161.2 [Other Products]
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 UniProt Primary Accession #    Q8WWZ1 [Other Products]
 UniProt Secondary Accession #    Q53SR9; Q56AT8; Q7RTZ5; Q969H5; Q9BYX1 [Other Products]
 UniProt Related Accession #    Q8WWZ1 [Other Products]
 Molecular Weight    ~18kD (SDS-PAGE) [Similar Products]
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 NCBI Official Full Name    interleukin-1 family member 10
 NCBI Official Synonym Full Names    interleukin 1 family, member 10 (theta)
 NCBI Official Symbol    IL1F10 [Similar Products]
 NCBI Official Synonym Symbols   
IL-38; FKSG75; IL1HY2; IL-1HY2; IL1-theta; FIL1-theta
[Similar Products]
 NCBI Protein Information    interleukin-1 family member 10; FIL1 theta; IL-1 theta; interleukin-1 HY2; IL-1F10 (canonical form IL-1F10a); interleukin-1 receptor antagonist FKSG75; interleukin-1 receptor antagonist-like FIL1 theta
 UniProt Protein Name    Interleukin-1 family member 10
 UniProt Synonym Protein Names   
Family of interleukin 1-theta; FIL1 theta; Interleukin-1 HY2; IL-1HY2; Interleukin-1 theta; IL-1 theta; Interleukin-38
 Protein Family    Interleukin-1 family
 UniProt Gene Name    IL1F10 [Similar Products]
 UniProt Synonym Gene Names    FIL1T; IL1HY2; IL38; IL-1F10; FIL1 theta; IL-1HY2; IL-1 theta; IL-38 [Similar Products]
 UniProt Entry Name    IL1FA_HUMAN
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 NCBI Summary for IL1F10    The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IL1F10    IL1F10: Binds soluble IL-1 receptor type 1. Belongs to the IL-1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: 2q13

Cellular Component: extracellular space

Molecular Function: interleukin-1 receptor binding; cytokine activity

Biological Process: cytokine and chemokine mediated signaling pathway
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 Research Articles on IL1F10    1. The IL1A locus was strongly associated with alkylosing spondyloarthritis phenotype, whereas IL1F10 was associated with non-alkylosing spondyloarthritis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL1F10 recombinant proteinDiseases associated with IL1F10 recombinant protein
 Reference Product  PubMed Publications
 IL1F8 recombinant protein  >3 publications with IL1F10 and IL1F8
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >6 publications with IL1F10 and Inflammation
 Heart Diseases Antibodies  >3 publications with IL1F10 and Heart Diseases
 Gastroenteritis Antibodies  >2 publications with IL1F10 and Gastroenteritis
 Necrosis Antibodies  >2 publications with IL1F10 and Necrosis
 Colitis Antibodies  >1 publications with IL1F10 and Colitis
 Intestinal Diseases Antibodies  >1 publications with IL1F10 and Intestinal Diseases
Organs/Tissues associated with IL1F10 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Placenta Antibodies  >1 publications with IL1F10 and Placenta
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