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IL16 recombinant protein

Scan QR to view Datasheet Catalog #    MBS203124
SDS-Page
Unit / Price
0.1 mg  /  $310 +1 FREE 8GB USB
0.5 mg  /  $720 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IL16, Recombinant Protein

 Also Known As   

IL16, 502-631aa, Human, His tag, E Coli

 Product Synonym Names    LCF; prIL-16; FLJ16806; FLJ42735; FLJ44234; HST19289; IL 16; Lymphocyte chemoattractant factor; HGNC:5980; Interleukin 16 precursor; PrIL16
 Product Gene Name   

IL16 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHHHHH SSGLVPRGSH MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS
 OMIM    AY324389 mRNA
 3D Structure    ModBase 3D Structure for Q14005
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 Host    E Coli
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 Purity/Purification    > 95% by SDS-PAGE
 Form/Format    Liquid in 20mM Tris pH 8.0, 1mM DTT, 10% glycerol
 Concentration    1 mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    Human
 Tag Information    His-tag
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of IL16 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for IL16 recombinant protein

   Interleukin-16 (IL16) is an immunomodulatory cytokine, which induces lymphocyte migration, expression of proinflammatory IL-1beta, IL6 and tumour necrosis factor-alpha (TNFalpha), and modulates apoptosis. This protein is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. Also, several central nervous system diseases and may play a role in promoting inflammatory responses. Recombinant human IL16, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
 Product Categories/Family for IL16 recombinant protein    Hormones & Cytokines
 Applications Tested/Suitable for IL16 recombinant protein   

SDS-PAGE

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 SDS-Page of IL16 recombinant protein    IL16 recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for IL16. It may not necessarily be applicable to this product.
 NCBI GI #    27262655
 NCBI GeneID    3603
 NCBI Accession #    NP_004504 [Other Products]
 NCBI GenBank Nucleotide #    NM_004513.5 [Other Products]
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 UniProt Primary Accession #    Q14005 [Other Products]
 UniProt Secondary Accession #    Q16435; Q6VVE6; Q6ZMQ7; Q9UP18; A6NM20; A8MU65; B5TY35; B9EGR6; H3BVH5 [Other Products]
 UniProt Related Accession #    Q14005 [Other Products]
 Molecular Weight    15.5kDa (150aa), confirmed by MALDI-TOF.
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 NCBI Official Full Name    pro-interleukin-16 isoform 1
 NCBI Official Synonym Full Names    interleukin 16
 NCBI Official Symbol    IL16 [Similar Products]
 NCBI Official Synonym Symbols   
LCF; NIL16; PRIL16; prIL-16
[Similar Products]
 NCBI Protein Information    pro-interleukin-16
 UniProt Protein Name    Pro-interleukin-16
 UniProt Synonym Protein Names   
Interleukin-16; IL-16
 Protein Family    Pro-interleukin
 UniProt Gene Name    IL16 [Similar Products]
 UniProt Synonym Gene Names    IL-16; LCF [Similar Products]
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 NCBI Summary for IL16    The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
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 UniProt Comments for IL16    Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.
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Product References and Citations for IL16 recombinant protein

   Bernstein HB., et al. (2006) J Immunol. 177 (6):3669-76.; McFadden C J., et al. (2007) J Immunol. 179 (10):6439-45.;
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 Research Articles on IL16    1. Data indicate an association between interleukin-16 (IL-16) rs4072111 and rs1131445 with progression to the severe stages (III-IV) of endometriosis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL16 recombinant proteinPathways associated with IL16 recombinant protein
 Reference Product  PubMed Publications
 CD4 recombinant protein  >230 publications with IL16 and CD4
 CCL5 recombinant protein  >41 publications with IL16 and CCL5
 CASP3 recombinant protein  >34 publications with IL16 and CASP3
 IL10 recombinant protein  >28 publications with IL16 and IL10
 CCR5 recombinant protein  >16 publications with IL16 and CCR5
 IL2 recombinant protein  >7 publications with IL16 and IL2
 IL2RA recombinant protein  >5 publications with IL16 and IL2RA
 MMP9 recombinant protein  >4 publications with IL16 and MMP9
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Signaling By Interleukins Pathway antibodies  Signaling By Interleukins Pathway Diagram
Diseases associated with IL16 recombinant proteinOrgans/Tissues associated with IL16 recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >136 publications with IL16 and Inflammation
 Hypersensitivity Antibodies  >75 publications with IL16 and Hypersensitivity
 Lung Diseases Antibodies  >68 publications with IL16 and Lung Diseases
 Necrosis Antibodies  >62 publications with IL16 and Necrosis
 Liver Diseases Antibodies  >14 publications with IL16 and Liver Diseases
 Heart Diseases Antibodies  >10 publications with IL16 and Heart Diseases
 Fibrosis Antibodies  >10 publications with IL16 and Fibrosis
 Kidney Diseases Antibodies  >8 publications with IL16 and Kidney Diseases
 Lung Injury Antibodies  >8 publications with IL16 and Lung Injury
 Lung Neoplasms Antibodies  >8 publications with IL16 and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >404 publications with IL16 and Blood
 Lung Antibodies  >66 publications with IL16 and Lung
 Skin Antibodies  >38 publications with IL16 and Skin
 Brain Antibodies  >35 publications with IL16 and Brain
 Liver Antibodies  >21 publications with IL16 and Liver
 Lymph Node Antibodies  >18 publications with IL16 and Lymph Node
 Lymph Antibodies  >18 publications with IL16 and Lymph
 Bone Marrow Antibodies  >12 publications with IL16 and Bone Marrow
 Intestine Antibodies  >12 publications with IL16 and Intestine
 Heart Antibodies  >11 publications with IL16 and Heart
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