NP_001158196
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
18.1kDa (181aa) confirmed by MALDI-TOF
NCBI Official Full Name
interleukin-33
NCBI Official Synonym Full Names
interleukin 33
NCBI Official Synonym Symbols
Il-33; Il1f11; NF-HEV; 9230117N10Rik [Similar Products]
NCBI Protein Information
interleukin-33
UniProt Protein Name
Interleukin-33
UniProt Synonym Gene Names
UniProt Comments for IL33
Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury.
Product References and Citations for IL33 active protein
Schmitz J., et al (2005) Immunity 23:479-490; Ali S., et al (2011) J. Immunol. 187:1609-1616
Research Articles on IL33
Precautions
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Disclaimer
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Products associated with IL33 active protein
Pathways associated with IL33 active protein
Diseases associated with IL33 active protein
Organs/Tissues associated with IL33 active protein
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