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Cxcl10 recombinant protein :: IP-10 (CXCL10) Recombinant Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS319057 Cxcl10 recombinant protein
Unit / Price
0.025 mg  /  $280 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IP-10 (CXCL10) Recombinant, Recombinant Protein

 Also Known As   

Human IP-10 (CXCL10) Recombinant

 Product Gene Name   

Cxcl10 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 5; NC_000071.5 (92775667..92777880, complement). Location: 5 E2; 5 53.0 cM
 3D Structure    ModBase 3D Structure for P17515
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 Host    E Coli
 Species Reactivity    Human
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 Specificity    IP-10 (CXCL10) Recombinant
 Purity/Purification    >95% pure (RP-HPLC and SDS-PAGE). Purified by chromatographic techniques
Product is sterile filtered.
 Form/Format    Purified, Lyophilized
Reconstitute with sterile deionized water to a concentration >100ug/ml. Further dilutions can be made in other aqueous buffers.
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 Inactivation    Not applicable
 Buffer    Not applicable
 Preservative    No
 Lyophilized    Yes
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 Preparation and Storage    The lyophilized product, though stable for 3 weeks at room temperature, is best stored at -20 degree C. After reconstitution, short term (up to 1 week) store at 2 to 8 degree C. Long term, add 0.1% HSA or BSA, aliquot and store at -20 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Cxcl10 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Cxcl10 recombinant protein

   Recombinant Human IP-10 (interferon-inducible protein of 10kDa, CXCL10)
Recombinant human IP-10 (CXCL10) is a single, non-glycosylated polypeptide containing 77 amino acids and having a molecular weight of 8516 Da. The sequence of the first five N-term
 Product Categories/Family for Cxcl10 recombinant protein    Purified Cytokines and Growth Factors
 Application Notes for Cxcl10 recombinant protein    Biological activity is determined by the dose dependent chemotaxis of human lymphocytes cultured in the presence of IL-2: ED50 = 5.0-20ng/ml. Each laboratory should determine an optimum working titer for use in its particular application. Other applicatio
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NCBI/Uniprot data below describe general gene information for Cxcl10. It may not necessarily be applicable to this product.
 NCBI GI #    976159
 NCBI GeneID    15945
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 UniProt Primary Accession #    P17515 [Other Products]
 UniProt Related Accession #    P17515; Q3U6X5; Q3UAS6; Q3UCV1; Q3UK71; Q548V9 [Other Products]
 Molecular Weight    10,789 Da [Similar Products]
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 NCBI Official Full Name    IP-10
 NCBI Official Synonym Full Names    chemokine (C-X-C motif) ligand 10
 NCBI Official Symbol    Cxcl10 [Similar Products]
 NCBI Official Synonym Symbols   
C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10
[Similar Products]
 NCBI Protein Information    C-X-C motif chemokine 10; gamma-IP10; OTTMUSP00000036425; interferon activated gene 10; small-inducible cytokine B10; interferon-gamma induced protein CRG-2; interferon-gamma-induced protein CRG-2; 10 kDa interferon gamma-induced protein; small inducible cytokine B subfamily (Cys-X-Cys), member 10
 UniProt Protein Name    C-X-C motif chemokine 10
 UniProt Synonym Protein Names   
10 kDa interferon gamma-induced protein; Gamma-IP10; IP-10; C7; Interferon-gamma induced protein CRG-2; Small-inducible cytokine B10
 Protein Family    C-X-C motif chemokine
 UniProt Gene Name    Cxcl10 [Similar Products]
 UniProt Synonym Gene Names    Crg2; Ifi10; Inp10; Scyb10 [Similar Products]
 UniProt Entry Name    CXL10_MOUSE
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 UniProt Comments for Cxcl10    Function: In addition to its role as a proinflammatory cytokine, may participate in T-cell effector function and perhaps T-cell development.

Subcellular location: Secreted.

Tissue specificity: Expressed in the spleen, thymus, lymph nodes and liver. Ref.5

Induction: By interferon gamma.

Sequence similarities: Belongs to the intercrine alpha (chemokine CxC) family.
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 Research Articles on Cxcl10    1. These results indicate that gammadelta T cells promote the resolution of fibrosis through the production of CXCL10.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Cxcl10 recombinant proteinPathways associated with Cxcl10 recombinant protein
 Reference Product  PubMed Publications
 Rela recombinant protein  >12 publications with Cxcl10 and Rela
 Carm1 recombinant protein  >1 publications with Cxcl10 and Carm1
 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
Diseases associated with Cxcl10 recombinant proteinOrgans/Tissues associated with Cxcl10 recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >675 publications with Cxcl10 and Inflammation
 Necrosis Antibodies  >424 publications with Cxcl10 and Necrosis
 Neoplasms Antibodies  >298 publications with Cxcl10 and Neoplasms
 Lung Diseases Antibodies  >203 publications with Cxcl10 and Lung Diseases
 Liver Diseases Antibodies  >115 publications with Cxcl10 and Liver Diseases
 Vascular Diseases Antibodies  >114 publications with Cxcl10 and Vascular Diseases
 Carcinoma Antibodies  >112 publications with Cxcl10 and Carcinoma
 Hepatitis Antibodies  >105 publications with Cxcl10 and Hepatitis
 Cardiovascular Diseases Antibodies  >104 publications with Cxcl10 and Cardiovascular Diseases
 Female Urogenital Diseases Antibodies  >84 publications with Cxcl10 and Female Urogenital Diseases
 Organ/Tissue Name  Pubmed Publications
 Lymph Node Antibodies  >120 publications with Cxcl10 and Lymph Node
 Spleen Antibodies  >93 publications with Cxcl10 and Spleen
 Bone Marrow Antibodies  >79 publications with Cxcl10 and Bone Marrow
 Intestine Antibodies  >64 publications with Cxcl10 and Intestine
 Eye Antibodies  >55 publications with Cxcl10 and Eye
 Thymus Antibodies  >45 publications with Cxcl10 and Thymus
 Embryonic Tissue Antibodies  >32 publications with Cxcl10 and Embryonic Tissue
 Mammary Gland Antibodies  >4 publications with Cxcl10 and Mammary Gland
 Epididymis Antibodies  >1 publications with Cxcl10 and Epididymis
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