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IGSF8 recombinant protein :: Immunoglobulin superfamily member 8 (IGSF8) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1420152 IGSF8 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $1,345 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,345 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,565 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,565 +1 FREE 8GB USB
1 mg (E-Coli)  /  $2,235 +2 FREE 8GB USB
0.1 mg (Baculovirus)  /  $2,235 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,700 +3 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,700 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Immunoglobulin superfamily member 8 (IGSF8), Recombinant Protein

 Also Known As   

Recombinant Human Immunoglobulin superfamily member 8 (IGSF8), partial

 Product Gene Name   

IGSF8 recombinant protein

[Similar Products]
 Product Synonym Gene Name    IGSF8 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    28-579
 Sequence    REV LVPEGPLYRV AGTAVSISCN VTGYEGPAQQ NFEWFLYRPE APDTALGIVS TKDTQFSYAV FKSRVVAGEV QVQRLQGDAV VLKIARLQAQ DAGIYECHTP STDTRYLGSY SGKVELRVLP DVLQVSAAPP GPRGRQAPTS PPRMTVHEGQ ELALGCLART STQKHTHLAV SFGRSVPEAP VGRSTLQEVV GIRSDLAVEA GAPYAERLAA GELRLGKEGT DRYRMVVGGA QAGDAGTYHC TAAEWIQDPD GSWAQIAEKR AVLAHVDVQT LSSQLAVTVG PGERRIGPGE PLELLCNVSG ALPPAGRHAA YSVGWEMAPA GAPGPGRLVA QLDTEGVGSL GPGYEGRHIA MEKVASRTYR LRLEAARPGD AGTYRCLAKA YVRGSGTRLR EAASARSRPL PVHVREEGVV LEAVAWLAGG TVYRGETASL LCNISVRGGP PGLRLAASWW VERPEDGELS SVPAQLVGGV GQDGVAELGV RPGGGPVSVE LVGPRSHRLR LHSLGPEDEG VYHCAPSAWV QHADYSWYQA GSARSGPVTV YPYMHALDT
 OMIM    606644
 3D Structure    ModBase 3D Structure for Q969P0
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of IGSF8 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for IGSF8. It may not necessarily be applicable to this product.
 NCBI GI #    331284207
 NCBI GeneID    93185
 NCBI Accession #    NP_001193594.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001206665.2 [Other Products]
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 UniProt Primary Accession #    Q969P0 [Other Products]
 UniProt Secondary Accession #    Q8NG09; Q96DP4; Q9BTG9 [Other Products]
 UniProt Related Accession #    Q969P0 [Other Products]
 Molecular Weight    55,808 Da
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 NCBI Official Full Name    immunoglobulin superfamily member 8
 NCBI Official Synonym Full Names    immunoglobulin superfamily member 8
 NCBI Official Symbol    IGSF8 [Similar Products]
 NCBI Official Synonym Symbols   
EWI2; PGRL; CD316; EWI-2; KCT-4; CD81P3; LIR-D1
[Similar Products]
 NCBI Protein Information    immunoglobulin superfamily member 8
 UniProt Protein Name    Immunoglobulin superfamily member 8
 UniProt Synonym Protein Names   
CD81 partner 3; Glu-Trp-Ile EWI motif-containing protein 2; EWI-2; Keratinocytes-associated transmembrane protein 4; KCT-4; LIR-D1; Prostaglandin regulatory-like protein; PGRL; CD_antigen: CD316
 Protein Family    Immunoglobulin superfamily
 UniProt Gene Name    IGSF8 [Similar Products]
 UniProt Synonym Gene Names    CD81P3; EWI2; KCT4; IgSF8; EWI-2; KCT-4; PGRL [Similar Products]
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 NCBI Summary for IGSF8    This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]
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 UniProt Comments for IGSF8    May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.
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 Research Articles on IGSF8    1. EWI-2 negatively regulates TGF-beta signaling and its downstream events including cytostasis (in vitro and in vivo), EMT-like changes, cell migration, CD271-dependent invasion, and lung metastasis (in vivo).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IGSF8 recombinant proteinDiseases associated with IGSF8 recombinant protein
 Reference Product  PubMed Publications
 CD9 recombinant protein  >17 publications with IGSF8 and CD9
 CD81 recombinant protein  >16 publications with IGSF8 and CD81
 CD82 recombinant protein  >2 publications with IGSF8 and CD82
 Disease Name  Pubmed Publications
 Hepatitis Antibodies  >4 publications with IGSF8 and Hepatitis
 Liver Diseases Antibodies  >1 publications with IGSF8 and Liver Diseases
Organs/Tissues associated with IGSF8 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4 publications with IGSF8 and Blood
 Vascular Antibodies  >4 publications with IGSF8 and Vascular
 Kidney Antibodies  >2 publications with IGSF8 and Kidney
 Embryonic Tissue Antibodies  >2 publications with IGSF8 and Embryonic Tissue
 Brain Antibodies  >2 publications with IGSF8 and Brain
 Ganglia Antibodies  >1 publications with IGSF8 and Ganglia
 Nerve Antibodies  >1 publications with IGSF8 and Nerve
 Lymph Antibodies  >1 publications with IGSF8 and Lymph
 Prostate Antibodies  >1 publications with IGSF8 and Prostate
 Lung Antibodies  >1 publications with IGSF8 and Lung
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