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NP recombinant protein :: Influenza A virus Nucleoprotein (NP) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS9423735
SDS-PAGE
Unit / Price
0.01 mg  /  $265 +1 FREE 8GB USB
0.05 mg  /  $350 +1 FREE 8GB USB
0.1 mg  /  $560 +1 FREE 8GB USB
0.2 mg  /  $880 +1 FREE 8GB USB
0.5 mg  /  $1,145 +1 FREE 8GB USB
1 mg  /  $1,795 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Influenza A virus Nucleoprotein (NP), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Influenza A virus Nucleoprotein (NP)

 Product Gene Name   

NP recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    Full Length, 1-498aa
 Sequence    MASQGTKRSY EQMETDGERQ NATEIRASVG KMIGGIGRFY IQMCTELKLS DYEGRLIQNS LTIERMVLSA FDE RRNKY LEEHPSAGKD PKKTGGPIYR RVNGKWMREL ILYDKEEIRR IWRQANNGDD ATAGLTHMMI WHSNLND A TYQRTRALVR TGMDPRMCSL MQGSTLPRRS GAAGAAVKGV GTMVMELVRM IKRGINDRNF WRGENGRKT RIAYERMCN ILKGKFQTAA QKAMMDQVRE SRNPGNAEFE DLTFLARSAL ILRGSVAHKS CLPACVYGPA VASG YDFE REGYSLVGID PFRLLQNSQV YSLIRPNENP AHKSQLVWMA CHSAAFEDLR VLSFIKGTKV LPRGKLSTR GVQIASNEN METMESSTLE LRSRYWAIRT RSGGNTNQQR ASAGQISIQP TFSVQRNLPF DRTTIMAAFN GNTE GRTS DMRTEIIRMM ESARPEDVSF QGRGVFELSD EKAASPIVPS FDMSNEGSYF FGDNAEEYDN
 3D Structure    ModBase 3D Structure for P03466
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 Host    E Coli
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 Purity/Purification    Greater than 80% as determined by SDS-PAGE.
 Form/Format    Tris-based buffer, 50% glycerol
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 Tag Info    N-terminal 6xHis-B2M-tagged
 Target Species    Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)
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 Preparation and Storage    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20 degree C/-80 degree C. The shelf life of lyophilized form is 12 months at -20 degree C/-80 degree C.
 Other Notes    Small volumes of NP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 SDS-PAGE of NP recombinant protein    NP recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for NP. It may not necessarily be applicable to this product.
 NCBI GI #    8486130
 NCBI GeneID    956531
 NCBI Accession #    NP_040982.1 [Other Products]
 NCBI GenBank Nucleotide #    NC_002019.1 [Other Products]
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 UniProt Primary Accession #    P03466 [Other Products]
 UniProt Secondary Accession #    Q20N34; Q58NB3; Q67228; Q80AB4 [Other Products]
 Molecular Weight    56.2kD
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 NCBI Official Full Name    nucleoprotein
 NCBI Official Symbol    NP [Similar Products]
 NCBI Protein Information    nucleoprotein
 UniProt Protein Name    Nucleoprotein
 UniProt Synonym Protein Names   
Nucleocapsid protein
 Protein Family    Nucleoprotein
 UniProt Gene Name    NP [Similar Products]
 UniProt Synonym Gene Names    Protein N [Similar Products]
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 UniProt Comments for NP    Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway. Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
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 Research Articles on NP    1. Structure of importin-alpha bound to a non-classical nuclear localization signal of the influenza A virus nucleoprotein has been reported.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with NP recombinant protein
 Products by Pathway  Pathway Diagram
 Assembly Of Viral Components At The Budding Site Pathway antibodies  Assembly Of Viral Components At The Budding Site Pathway Diagram
 Budding Pathway antibodies  Budding Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Entry Of Influenza Virion Into Host Cell Via Endocytosis Pathway antibodies  Entry Of Influenza Virion Into Host Cell Via Endocytosis Pathway Diagram
 Export Of Viral Ribonucleoproteins From Nucleus Pathway antibodies  Export Of Viral Ribonucleoproteins From Nucleus Pathway Diagram
 Fusion And Uncoating Of The Influenza Virion Pathway antibodies  Fusion And Uncoating Of The Influenza Virion Pathway Diagram
 Fusion Of The Influenza Virion To The Host Cell Endosome Pathway antibodies  Fusion Of The Influenza Virion To The Host Cell Endosome Pathway Diagram
 Infectious Disease Pathway antibodies  Infectious Disease Pathway Diagram
 Influenza A Virus Infection Pathway antibodies  Influenza A Virus Infection Pathway Diagram
 Influenza Infection Pathway antibodies  Influenza Infection Pathway Diagram
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