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Ins2 recombinant protein :: Insulin-2 (Ins2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1083287 Ins2 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $475 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $635 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $700 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $810 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $880 +1 FREE 8GB USB
1 mg (E-Coli)  /  $990 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $990 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,015 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,045 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,480 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,500 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,600 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $1,985 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Insulin-2 (Ins2), Recombinant Protein

 Also Known As   

Recombinant Mouse Insulin-2 (Ins2)

 Product Gene Name   

Ins2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    25-110aa, Cytoplasmic domain
 Sequence    FVKQHLCGSH LVEALYLVCG ERGFFYTPMS RREVEDPQVA QLELGGGPGA GDLQTLALEV AQQKRGIVDQ CCTSICSLYQ LENYCN
 3D Structure    ModBase 3D Structure for P01326
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mouse
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Ins2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Ins2. It may not necessarily be applicable to this product.
 NCBI GI #    297374794
 NCBI GeneID    16334
 NCBI Accession #    NP_001172012.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001185083.2 [Other Products]
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 UniProt Primary Accession #    P01326 [Other Products]
 UniProt Related Accession #    P01326 [Other Products]
 Molecular Weight    12,364 Da
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 NCBI Official Full Name    insulin-2 preproprotein
 NCBI Official Synonym Full Names    insulin II
 NCBI Official Symbol    Ins2 [Similar Products]
 NCBI Official Synonym Symbols   
Mody; Ins-2; InsII; Mody4; AA986540
[Similar Products]
 NCBI Protein Information    insulin-2
 UniProt Protein Name    Insulin-2
 Protein Family    Insulin
 UniProt Gene Name    Ins2 [Similar Products]
 UniProt Synonym Gene Names    Ins-2 [Similar Products]
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 NCBI Summary for Ins2    This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. The encoded precursor protein undergoes proteolytic cleavage to produce a disulfide-linked heterodimeric functional protein that is stored in secretory granules. An increase in blood glucose levels, among others, induces the release of insulin from the secretory granules. Mice deficient in the functional hormone encoded by this gene develop diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
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 UniProt Comments for Ins2    Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
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 Research Articles on Ins2    1. Data (including data from studies using knockout mice) suggest that Ins1 and Ins2 are required for pancreatic beta-cell maturation; thus, Ins1 and Ins2 are needed for normal beta-cell development and for maintenance of normal beta-cell function.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Ins2 recombinant proteinPathways associated with Ins2 recombinant protein
 Reference Product  PubMed Publications
 Ins1 recombinant protein  >56 publications with Ins2 and Ins1
 Irs2 recombinant protein  >3 publications with Ins2 and Irs2
 Irs1 recombinant protein  >2 publications with Ins2 and Irs1
 Iapp recombinant protein  >1 publications with Ins2 and Iapp
 Insr recombinant protein  >1 publications with Ins2 and Insr
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Amyloids Pathway antibodies  Amyloids Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 HIF-1 Signaling Pathway antibodies  HIF-1 Signaling Pathway Diagram
 IRS Activation Pathway antibodies  IRS Activation Pathway Diagram
 IRS-related Events Pathway antibodies  IRS-related Events Pathway Diagram
 Insulin Processing Pathway antibodies  Insulin Processing Pathway Diagram
 Insulin Receptor Recycling Pathway antibodies  Insulin Receptor Recycling Pathway Diagram
Diseases associated with Ins2 recombinant proteinOrgans/Tissues associated with Ins2 recombinant protein
 Disease Name  Pubmed Publications
 Diabetes Mellitus Antibodies  >126 publications with Ins2 and Diabetes Mellitus
 Glucose Metabolism Disorders Antibodies  >119 publications with Ins2 and Glucose Metabolism Disorders
 Disease Models, Animal Antibodies  >73 publications with Ins2 and Disease Models, Animal
 Hyperglycemia Antibodies  >56 publications with Ins2 and Hyperglycemia
 Diabetes Mellitus, Type 1 Antibodies  >53 publications with Ins2 and Diabetes Mellitus, Type 1
 Diabetic Nephropathies Antibodies  >28 publications with Ins2 and Diabetic Nephropathies
 Insulin Resistance Antibodies  >18 publications with Ins2 and Insulin Resistance
 Inflammation Antibodies  >8 publications with Ins2 and Inflammation
 Hyperplasia Antibodies  >7 publications with Ins2 and Hyperplasia
 Hypertrophy Antibodies  >7 publications with Ins2 and Hypertrophy
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >69 publications with Ins2 and Pancreas
 Embryonic Tissue Antibodies  >14 publications with Ins2 and Embryonic Tissue
 Intestine Antibodies  >3 publications with Ins2 and Intestine
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