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Add To Compare List IGFBP5 active protein :: Insulin-like growth factor-binding protein 5 protein (IGFBP5) Active Protein Catalog # MBS969368 Unit / Price 0.005 mg / $220 +1 FREE 8GB USB 0.1 mg / $975 +1 FREE 8GB USB 0.5 mg / $2,050 +2 FREE 8GB USB 5x0.5 mg / $9,000 +10 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Insulin-like growth factor-binding protein 5 protein (IGFBP5), Active Protein Popular Item Full Product Name Recombinant Human Insulin-like growth factor-binding protein 5 protein (IGFBP5) (Active) Product Synonym Names IBP-5; IGFBP-5 Product Gene Name IGFBP5 active protein[Similar Products] Product Synonym Gene Name IBP5[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence Positions 21-272aa Sequence LGSFVHCEPC DEKALSMCPP SPLGCELVKE PGCGCCMTCA LAEGQSCGVY TERCAQGLRC LPRQDEEKPL HALLHGRGVC LNEKSYREQV KIERDSREHE EPTTSEMAEE TYSPKIFRPK HTRISELKAE AVKKDRRKKL TQSKFVGGAE NTAHPRIISA PEMRQESEQG PCRRHMEASL QELKASPRMV PRAVYLPNCD RKGFYKRKQC KPSRGRKRGI CWCVDKYGMK LPGMEYVDGD FQCHTFDSSN VE OMIM M65062 mRNA 3D Structure ModBase 3D Structure for P24593 Host E Coli Purity/Purification Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific) Form/Format Lyophilized Species Homo sapiens (Human) Biological Activity Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit IGF-II induced proliferation of MCF-7 cells is less than 0.4 ug/ml, corresponding to a specific activity of > 2500 IU/mg in the presence of 15 ng/ml of rHuIGF-II. Endotoxin Less than 1.0 EU/ug as determined by LAL method. Protein Note Protein will be provided with aseptic processing and endotoxin removal. Preparation and Storage Generally, the shelf life of liquid form is 6 months at -20/-80 degree C. The shelf life of lyophilized form is 12 months at -20/-80 degree C. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Active Protein Note Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product. Other Notes Small volumes of IGFBP5 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for IGFBP5 active protein IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Product Categories/Family for IGFBP5 active protein Biological Active Protein; Cancer; Growth Factor SDS-PAGE of IGFBP5 active protein (Note: Representative image, actual molecular weight may vary depending on Tag type and expression host) TOP NCBI/Uniprot data below describe general gene information for IGFBP5. It may not necessarily be applicable to this product. NCBI GI # 10834982 NCBI GeneID 3488 NCBI Accession # NP_000590.1 [Other Products] NCBI GenBank Nucleotide # NM_000599.3 [Other Products] UniProt Primary Accession # P24593 [Other Products] UniProt Secondary Accession # Q5U0A3[Other Products] UniProt Related Accession # P24593[Other Products] Molecular Weight 28.6 kDa TOP NCBI Official Full Name insulin-like growth factor-binding protein 5 NCBI Official Synonym Full Names insulin like growth factor binding protein 5 NCBI Official Symbol IGFBP5 [Similar Products] NCBI Official Synonym Symbols IBP5 [Similar Products] NCBI Protein Information insulin-like growth factor-binding protein 5 UniProt Protein Name Insulin-like growth factor-binding protein 5 Protein Family Insulin-like growth factor-binding protein UniProt Gene Name IGFBP5 [Similar Products] UniProt Synonym Gene Names IBP5; IBP-5; IGF-binding protein 5; IGFBP-5 [Similar Products] TOP TOP UniProt Comments for IGFBP5 IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Research Articles on IGFBP5 1. dysregulation of DNMT3A and IGFBP5 is relevant to preeclampsia. Thus, we propose that DNMT3A and IGFBP5 can serve as potential markers and targets for the clinical diagnosis and therapy of preeclampsia. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with IGFBP5 active protein Reference Product PubMed Publications IGF1 active protein >34 publications with IGFBP5 and IGF1 IGF2 active protein >22 publications with IGFBP5 and IGF2 PTH active protein >20 publications with IGFBP5 and PTH PAPPA2 active protein >10 publications with IGFBP5 and PAPPA2 THBS1 active protein >4 publications with IGFBP5 and THBS1 FHL2 active protein >4 publications with IGFBP5 and FHL2 SERPINE1 active protein >1 publications with IGFBP5 and SERPINE1 Pathways associated with IGFBP5 active protein Products by Pathway Pathway Diagram Metabolism Of Proteins Pathway antibodies Metabolism Of Proteins Pathway Diagram Myometrial Relaxation And Contraction Pathways antibodies Myometrial Relaxation And Contraction Pathways Diagram Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway antibodies Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway Diagram Senescence And Autophagy Pathway antibodies Senescence And Autophagy Pathway Diagram Diseases associated with IGFBP5 active protein Disease Name Pubmed Publications Carcinoma Antibodies >53 publications with IGFBP5 and Carcinoma Breast Neoplasms Antibodies >53 publications with IGFBP5 and Breast Neoplasms Nervous System Diseases Antibodies >39 publications with IGFBP5 and Nervous System Diseases Inflammation Antibodies >24 publications with IGFBP5 and Inflammation Brain Diseases Antibodies >23 publications with IGFBP5 and Brain Diseases Cardiovascular Diseases Antibodies >23 publications with IGFBP5 and Cardiovascular Diseases Necrosis Antibodies >23 publications with IGFBP5 and Necrosis Hypertrophy Antibodies >22 publications with IGFBP5 and Hypertrophy Fibrosis Antibodies >19 publications with IGFBP5 and Fibrosis Neoplasms, Experimental Antibodies >18 publications with IGFBP5 and Neoplasms, Experimental Organs/Tissues associated with IGFBP5 active protein Organ/Tissue Name Pubmed Publications Muscle Antibodies >154 publications with IGFBP5 and Muscle Bone Antibodies >133 publications with IGFBP5 and Bone Ovary Antibodies >70 publications with IGFBP5 and Ovary Vascular Antibodies >56 publications with IGFBP5 and Vascular Liver Antibodies >55 publications with IGFBP5 and Liver Connective Tissue Antibodies >55 publications with IGFBP5 and Connective Tissue Brain Antibodies >55 publications with IGFBP5 and Brain Mammary Gland Antibodies >47 publications with IGFBP5 and Mammary Gland Kidney Antibodies >43 publications with IGFBP5 and Kidney Embryonic Tissue Antibodies >41 publications with IGFBP5 and Embryonic Tissue TOP © 2006-24 MyBioSource.com. 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