NP_497650.4
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
115,345 Da
NCBI Official Full Name
Insulin-like receptor subunit beta
NCBI Protein Information
Insulin-like receptor subunit beta; Receptor protein-tyrosine kinase; hypothetical protein
UniProt Protein Name
Insulin-like receptor
UniProt Synonym Protein Names
Abnormal dauer formation protein 2
UniProt Synonym Gene Names
UniProt Comments for daf-2
Insulin receptor-like tyrosine kinase which regulates metabolism, controls longevity and prevents developmental arrest at the dauer stage (PubMed:9252323, PubMed:9790527, PubMed:24332851). Binding of INS family members may either stimulate, or antagonize, association of the receptor with downstream mediators such as pdk-1 and age-1 (PubMed:11274053). Required for germline progenitor proliferation during larval development (PubMed:22278922). Required for the response to environmental stimuli such as food, pheromone, and temperature. Negatively regulates resistance to UV and oxidative stress (PubMed:24332851). Role in immune function and pathogen resistance (PubMed:18782349). Negatively regulates autophagy (PubMed:22560223). Regulates daf-18/PTEN protein levels (PubMed:23995781).
Research Articles on daf-2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with daf-2 recombinant protein
Pathways associated with daf-2 recombinant protein
Diseases associated with daf-2 recombinant protein
Organs/Tissues associated with daf-2 recombinant protein
|