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IFNG recombinant protein :: Interferon gamma Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS203080
SDS-Page
Unit / Price
0.1 mg  /  $255 +1 FREE 8GB USB
0.5 mg  /  $535 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interferon gamma (IFNG), Recombinant Protein

★Popular Item★
 Also Known As   

Interferon gamma, 24-166 aa, Human, E Coli (Bioactivity Validated)

 Product Synonym Names    Ifng; Interferon-g; IFN-gamma; Interferon gamma; IFNG; IFG; IFI; IFN gamma; IFN immune; Immune interferon; Interferon gamma precursor; Macrophage activating factor; MAF; T Cell interferon; Type II Interferon
 Product Gene Name   

IFNG recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFRGR RASQ
 OMIM    X13274 mRNA
 3D Structure    ModBase 3D Structure for P01579
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 Host    E Coli
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 Purity/Purification    > 95% by SDS-PAGE
 Form/Format    Liquid. In phosphate-buffered saline (pH 7.4), 10% glycerol.
 Concentration    1 mg/ml (determined by Absorbance at 280nm) (lot specific)
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 Antigen Species    Human
 Endotoxin Level    < 1.0 EU per 1 microgram of protein (determined by LAL method)
 Biological Activity    Measured in a cytotoxicity assay using WiDr cells. The ED50 for this effect is less or equal to 5 ng/ml.
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of IFNG recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for IFNG recombinant protein

   Nature human interferon-gamma is composed of 143amino acid residues without cysteine residues and is glycosylated. Recombinant human interferon-gamma was expressed in E Coli and purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Additional amino acid (Methionine) is attached at N-terminus.
 Product Categories/Family for IFNG recombinant protein    Hormones & Cytokines
 Applications Tested/Suitable for IFNG recombinant protein   

SDS-PAGE

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 SDS-Page of IFNG recombinant protein    IFNG recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for IFNG. It may not necessarily be applicable to this product.
 NCBI GI #    56786138
 NCBI GeneID    3458
 NCBI Accession #    NP_000610 [Other Products]
 NCBI GenBank Nucleotide #    NM_000619.2 [Other Products]
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 UniProt Primary Accession #    P01579 [Other Products]
 UniProt Secondary Accession #    Q53ZV4; B5BU88 [Other Products]
 UniProt Related Accession #    P01579 [Other Products]
 Molecular Weight    16.9kDa (144aa), confirmed by MALDI-TOF. [Similar Products]
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 NCBI Official Full Name    interferon gamma
 NCBI Official Synonym Full Names    interferon gamma
 NCBI Official Symbol    IFNG [Similar Products]
 NCBI Official Synonym Symbols   
IFG; IFI
[Similar Products]
 NCBI Protein Information    interferon gamma
 UniProt Protein Name    Interferon gamma
 UniProt Synonym Protein Names   
Immune interferon
 Protein Family    Interferon
 UniProt Gene Name    IFNG [Similar Products]
 UniProt Synonym Gene Names    IFN-gamma [Similar Products]
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 NCBI Summary for IFNG    This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]
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 UniProt Comments for IFNG    Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
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Product References and Citations for IFNG recombinant protein

   Sen GC, Lengyel P (1992) J. Biol. Chem. 267 (8):5017-5020; Tsutomu Arakawa, Yeuh-Rong Hsu (1987) Biochemistry. 26:5428-5432; Ernst Rinderknecht, et al (1984) J. Biol. Chem. 259 (11):6790-6797;
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 Research Articles on IFNG    1. Results showed that IFNG upregulated PD-L1 expression in gastric cancer cells mainly through JAK-STAT pathway.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IFNG recombinant proteinPathways associated with IFNG recombinant protein
 Reference Product  PubMed Publications
 IL2 recombinant protein  >107 publications with IFNG and IL2
 TBX21 recombinant protein  >80 publications with IFNG and TBX21
 STAT1 recombinant protein  >73 publications with IFNG and STAT1
 IL18 recombinant protein  >44 publications with IFNG and IL18
 IFNGR1 recombinant protein  >43 publications with IFNG and IFNGR1
 IRF1 recombinant protein  >23 publications with IFNG and IRF1
 CD86 recombinant protein  >10 publications with IFNG and CD86
 IL23A recombinant protein  >4 publications with IFNG and IL23A
 IFNA17 recombinant protein  >3 publications with IFNG and IFNA17
 IFNA2 recombinant protein  >3 publications with IFNG and IFNA2
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 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
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 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
Diseases associated with IFNG recombinant proteinOrgans/Tissues associated with IFNG recombinant protein
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >272 publications with IFNG and Necrosis
 Autoimmune Diseases Antibodies  >154 publications with IFNG and Autoimmune Diseases
 Respiratory Tract Diseases Antibodies  >144 publications with IFNG and Respiratory Tract Diseases
 Hepatitis Antibodies  >68 publications with IFNG and Hepatitis
 Lymphoproliferative Disorders Antibodies  >44 publications with IFNG and Lymphoproliferative Disorders
 Multiple Sclerosis Antibodies  >37 publications with IFNG and Multiple Sclerosis
 HIV Infections Antibodies  >33 publications with IFNG and HIV Infections
 Colitis Antibodies  >33 publications with IFNG and Colitis
 Arthritis, Rheumatoid Antibodies  >31 publications with IFNG and Arthritis, Rheumatoid
 Hepatitis C Antibodies  >29 publications with IFNG and Hepatitis C
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >973 publications with IFNG and Blood
 Kidney Antibodies  >72 publications with IFNG and Kidney
 Lymph Node Antibodies  >47 publications with IFNG and Lymph Node
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