Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow pIL 1 alpha  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • IRTKS Antibody
 • PKR1 ELISA Kit
 • Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) ELISA Kit
 • Major allergen Mal d 1 (MALD1) Recombinant Protein
 • 26S proteasome non-ATPase regulatory subunit 4 (PSMD4) Recombinant Protein
 • laminin, beta 1 (LAMB1) ELISA Kit
 • Interleukin 26, IL-26 (IL26) ELISA Kit
 • RUNX3 Antibody
 • Interferon Regulatory Factor-2 (IRF 2) Recombinant Protein
 • TP73 Antibody
 • Parvalbumin A (PALB A) ELISA Kit
 • Ethanol Assay Kit
 • Phosphatidylcholine Antibody (IgA) ELISA Kit
 • Aflatoxin M1 ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

pIL 1 alpha recombinant protein :: Interleukin-1 alpha Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS142272 pIL 1 alpha recombinant protein
Unit / Price
0.002 mg  /  $140 +1 FREE 8GB USB
0.01 mg  /  $205 +1 FREE 8GB USB
0.1 mg  /  $1,305 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin-1 alpha (pIL 1 alpha), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Porcine Interleukin-1 alpha

 Product Synonym Names    IL 1 alpha Porcine; Interleukin-1 alpha Porcine Recombinant; Hematopoietin-1; Lymphocyte-activating factor (LAF); Endogenous Pyrogen (EP); Leukocyte Endogenous Mediator (LEM); Mononuclear Cell Factor (MCF); IL-1 alpha; IL1; IL-1A; IL1F1
 Product Gene Name   

pIL 1 alpha recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence    The sequence of the first five N-terminal amino acids was determined and was found to be Ser-Ala-Th r-Tyr-Ser
 3D Structure    ModBase 3D Structure for P18430
Section Bar
 Host    E Coli
Section Bar
 Purity/Purification    Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
 Form/Format    The protein was lyophilized from a concentrated (1mg/ml) sterile solution containing no additives.
Sterile Filtered White lyophilized (freeze-dried) powder.
Section Bar
 Solubility    It is recommended to reconstitute the lyophilized Interleukin-1 alpha in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
 Protein Content    Protein quantitation was carried out by two independent methods:1. UV spectroscopy at 280 nm using the absorbency value of 0.669 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a standard solution of IL-1 as a Reference Standard.
 Biological Activity    The ED50 as determined by the dose-dependant stimulation of D10S cells is < 0.03 ng/ml.
Section Bar
 Preparation and Storage    Lyophilized Interleukin-1 alpha although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution IL1A should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
 Other Notes    Small volumes of pIL 1 alpha recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for pIL 1 alpha recombinant protein

   Description: Interleukin-1A Porice Recombinant produced in E Coli is single, a non-glycosylated, Polypeptide chain containing 158 amino acids and having a molecular mass of 18076 Dalton. The IL-1A is purified by proprietary chromatographic techniques.

Introduction: Interleukin-1 alpha is a proinflammatory cytokine produced by a wide variety of cell types, including macrophages, osteoblasts, monocytes and hepatocytes. Circulating levels of are normally low and only rise after stimulation by agents such as those produced byinflammation, infection or microbial endotoxins. IL-1 alpha possesses a wide variety of biological activities and exerts its effects by binding to specific cell surface receptors.
 Product Categories/Family for pIL 1 alpha recombinant protein    CYTOKINES AND GROWTH FACTORS; Cytokines; Interleukin
NCBI/Uniprot data below describe general gene information for pIL 1 alpha. It may not necessarily be applicable to this product.
 NCBI GI #    47522878
 NCBI GeneID    397094
 NCBI Accession #    NP_999194.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_214029.1 [Other Products]
Section Bar
 UniProt Primary Accession #    P18430 [Other Products]
 UniProt Related Accession #    P18430 [Other Products]
 Molecular Weight    30,789 Da
Table BarTOPTable Bar
 NCBI Official Full Name    interleukin-1 alpha
 NCBI Official Symbol    IL1A [Similar Products]
 NCBI Official Synonym Symbols   
IL-1alpha
[Similar Products]
 NCBI Protein Information    interleukin-1 alpha; IL-1 alpha; interleukin 1-alpha
 UniProt Protein Name    Interleukin-1 alpha
 Protein Family    Interleukin
 UniProt Gene Name    IL1A [Similar Products]
 UniProt Synonym Gene Names    IL-1 alpha [Similar Products]
 UniProt Entry Name    IL1A_PIG
Section Bar
 UniProt Comments for pIL 1 alpha    Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Table BarTOPTable Bar
 Research Articles on pIL 1 alpha    1. Constitutive suppression of IL-1alpha maintains quiescence of endothelium and that terminal complement complexes remove that suppression, allowing IL-1alpha transcription and, ultimately, activation of endothelium to proceed.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with pIL 1 alpha recombinant proteinPathways associated with pIL 1 alpha recombinant protein
 Reference Product  PubMed Publications
 IL6 recombinant protein  >94 publications with pIL 1 alpha and IL6
 IL-1beta recombinant protein  >86 publications with pIL 1 alpha and IL-1beta
 TNF recombinant protein  >72 publications with pIL 1 alpha and TNF
 IL1R1 recombinant protein  >16 publications with pIL 1 alpha and IL1R1
 NOS2 recombinant protein  >5 publications with pIL 1 alpha and NOS2
 MYD88 recombinant protein  >4 publications with pIL 1 alpha and MYD88
 IL1R2 recombinant protein  >3 publications with pIL 1 alpha and IL1R2
 TRAF6 recombinant protein  >2 publications with pIL 1 alpha and TRAF6
 NOD1 recombinant protein  >1 publications with pIL 1 alpha and NOD1
 IRAK4 recombinant protein  >1 publications with pIL 1 alpha and IRAK4
 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Graft-versus-host Disease Pathway antibodies  Graft-versus-host Disease Pathway Diagram
 Graft-versus-host Disease Pathway antibodies  Graft-versus-host Disease Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
Diseases associated with pIL 1 alpha recombinant proteinOrgans/Tissues associated with pIL 1 alpha recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >85 publications with pIL 1 alpha and Inflammation
 Necrosis Antibodies  >59 publications with pIL 1 alpha and Necrosis
 Skin Diseases Antibodies  >32 publications with pIL 1 alpha and Skin Diseases
 Pain Antibodies  >8 publications with pIL 1 alpha and Pain
 Heart Diseases Antibodies  >8 publications with pIL 1 alpha and Heart Diseases
 Kidney Diseases Antibodies  >8 publications with pIL 1 alpha and Kidney Diseases
 Lung Neoplasms Antibodies  >7 publications with pIL 1 alpha and Lung Neoplasms
 Fibrosis Antibodies  >6 publications with pIL 1 alpha and Fibrosis
 Liver Diseases Antibodies  >6 publications with pIL 1 alpha and Liver Diseases
 Hypertension Antibodies  >5 publications with pIL 1 alpha and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >69 publications with pIL 1 alpha and Blood
 Lung Antibodies  >20 publications with pIL 1 alpha and Lung
 Spleen Antibodies  >1 publications with pIL 1 alpha and Spleen
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions