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IL-13 recombinant protein :: Interleukin-13 (IL-13) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS343061 IL-13 recombinant protein
Unit / Price
0.01 mg  /  $225 +1 FREE 8GB USB
0.1 mg  /  $590 +1 FREE 8GB USB
1 mg  /  $2,685 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin-13 (IL-13), Recombinant Protein

★Popular Item★
 Also Known As   

Interleukin-13 (IL-13)

 Product Synonym Names    IL-13; ALRH, P600; Interleukin-13
 Product Gene Name   

IL-13 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    147683
 3D Structure    ModBase 3D Structure for P35225
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 Purity/Purification    >95% by SDS-PAGE
 Form/Format    Liquid
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 Buffer    Buffered 50% glycerol
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 ISO Certification    Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
 Other Notes    Small volumes of IL-13 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for IL-13 recombinant protein

   Interleukin-13 is a pleiotropic regulatory cytokine, which shares many of the properties of Interleukin-4. IL-13 is produced primarily by activated T lymphocytes and acts via specific cell surface receptor complexes. Its biological activities include the stimulation of B-cell proliferation and differentiation and the regulation of inflammatory and immune responses. Recombinant Interleukin-13 comprises a 112 amino acid fragment (21-132) corresponding to the mature Interleukin-13 110R form of the protein and is expressed in E Coli with an amino-terminal hexahistidine tag. This product is not intended for therapeutic use.
 Product Categories/Family for IL-13 recombinant protein    Recombinant Proteins; Interleukin-13
NCBI/Uniprot data below describe general gene information for IL-13. It may not necessarily be applicable to this product.
 NCBI GI #    26787978
 NCBI GeneID    3596
 NCBI Accession #    NP_002179.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002188.2 [Other Products]
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 UniProt Primary Accession #    P35225 [Other Products]
 UniProt Secondary Accession #    O43644; Q4VB52; Q9UDC7 [Other Products]
 UniProt Related Accession #    P35225 [Other Products]
 Molecular Weight    15,816 Da
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 NCBI Official Full Name    interleukin-13
 NCBI Official Synonym Full Names    interleukin 13
 NCBI Official Symbol    IL13 [Similar Products]
 NCBI Official Synonym Symbols   
P600; IL-13
[Similar Products]
 NCBI Protein Information    interleukin-13
 UniProt Protein Name    Interleukin-13
 Protein Family    Interleukin
 UniProt Gene Name    IL13 [Similar Products]
 UniProt Synonym Gene Names    NC30; IL-13 [Similar Products]
 UniProt Entry Name    IL13_HUMAN
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 NCBI Summary for IL-13    This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IL-13    IL13: Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH). Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure. Belongs to the IL-4/IL-13 family.

Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: extracellular region; extracellular space

Molecular Function: interleukin-13 receptor binding; protein binding

Biological Process: cell motility; cell-cell signaling; positive regulation of B cell proliferation; positive regulation of immunoglobulin production; positive regulation of macrophage activation; positive regulation of mast cell degranulation

Disease: Allergic Rhinitis; Asthma, Susceptibility To
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Product References and Citations for IL-13 recombinant protein

   Zurawski, G. & de Vries, J.E. (1994) Immunology Today 15(1): 19-26.
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 Research Articles on IL-13    1. Data show that single nucleotide polymorphisms (SNPs) rs848 in the interleukin 13 (IL13) gene region is significantly associated with a continuous measure of symptom severity in adult subjects with ever asthma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL-13 recombinant proteinPathways associated with IL-13 recombinant protein
 Reference Product  PubMed Publications
 STAT6 recombinant protein  >466 publications with IL-13 and STAT6
 IL13RA1 recombinant protein  >307 publications with IL-13 and IL13RA1
 IL5 recombinant protein  >169 publications with IL-13 and IL5
 GATA3 recombinant protein  >116 publications with IL-13 and GATA3
 IL18 recombinant protein  >100 publications with IL-13 and IL18
 IL4R recombinant protein  >80 publications with IL-13 and IL4R
 TSLP recombinant protein  >51 publications with IL-13 and TSLP
 IL3 recombinant protein  >22 publications with IL-13 and IL3
 VCAM1 recombinant protein  >6 publications with IL-13 and VCAM1
 Products by Pathway  Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response Pathway antibodies  Cytokines And Inflammatory Response Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 Glucocorticoid Receptor Regulatory Network Pathway antibodies  Glucocorticoid Receptor Regulatory Network Pathway Diagram
 IL12 Signaling Mediated By STAT4 Pathway antibodies  IL12 Signaling Mediated By STAT4 Pathway Diagram
Diseases associated with IL-13 recombinant proteinOrgans/Tissues associated with IL-13 recombinant protein
 Disease Name  Pubmed Publications
 Hypersensitivity Antibodies  >1594 publications with IL-13 and Hypersensitivity
 Inflammation Antibodies  >1581 publications with IL-13 and Inflammation
 Asthma Antibodies  >1461 publications with IL-13 and Asthma
 Hypersensitivity, Immediate Antibodies  >1396 publications with IL-13 and Hypersensitivity, Immediate
 Lung Diseases Antibodies  >1380 publications with IL-13 and Lung Diseases
 Respiratory Hypersensitivity Antibodies  >1153 publications with IL-13 and Respiratory Hypersensitivity
 Necrosis Antibodies  >716 publications with IL-13 and Necrosis
 Fibrosis Antibodies  >398 publications with IL-13 and Fibrosis
 Bronchial Hyperreactivity Antibodies  >246 publications with IL-13 and Bronchial Hyperreactivity
 Dermatitis, Atopic Antibodies  >221 publications with IL-13 and Dermatitis, Atopic
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >212 publications with IL-13 and Brain
 Bone Marrow Antibodies  >170 publications with IL-13 and Bone Marrow
 Mixed Antibodies  >76 publications with IL-13 and Mixed
 Testis Antibodies  >8 publications with IL-13 and Testis
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