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IL13 recombinant protein :: Interleukin 13 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2034519 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment) IL13 recombinant protein
Unit / Price
0.01 mg  /  $150 +1 FREE 8GB USB
0.05 mg  /  $285 +1 FREE 8GB USB
0.1 mg  /  $445 +1 FREE 8GB USB
0.2 mg  /  $550 +1 FREE 8GB USB
0.5 mg  /  $1,060 +1 FREE 8GB USB
1 mg  /  $1,580 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin 13 (IL13), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Interleukin 13 (IL13)

 Product Gene Name   

IL13 recombinant protein

[Similar Products]
 Product Synonym Gene Name    ALRH; BHR1; P600; IL-13; NC30 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    147683
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 Host    E Coli
Source: Prokaryotic expression
 Species Reactivity    Mouse
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 Purity/Purification    > 90%
 Form/Format    Freeze-dried powder
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 Usage    Reconstitute in PBS or others.
 Endotoxin Level    < 1.0EU per 1ug (determined by the LAL method)
 Buffer Formulation    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
 Residues & Tags    N-terminal His Tag
 Subcellular Location    Secreted
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 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of IL13 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for IL13 recombinant protein   

SDS-PAGE; Western Blot (WB); ELISA (EIA); Immunoprecipitation (IP)

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NCBI/Uniprot data below describe general gene information for IL13. It may not necessarily be applicable to this product.
 NCBI GI #    26787978
 NCBI GeneID    3596
 NCBI Accession #    NP_002179.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002188.2 [Other Products]
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 UniProt Secondary Accession #    O43644; Q4VB52; Q9UDC7 [Other Products]
 UniProt Related Accession #    P35225 [Other Products]
 Molecular Weight    15,816 Da
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 NCBI Official Full Name    interleukin-13
 NCBI Official Synonym Full Names    interleukin 13
 NCBI Official Symbol    IL13 [Similar Products]
 NCBI Official Synonym Symbols   
P600; IL-13
[Similar Products]
 NCBI Protein Information    interleukin-13
 UniProt Protein Name    Interleukin-13
 Protein Family    Interleukin
 UniProt Gene Name    IL13 [Similar Products]
 UniProt Synonym Gene Names    NC30; IL-13 [Similar Products]
 UniProt Entry Name    IL13_HUMAN
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 NCBI Summary for IL13    This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IL13    IL13: Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH). Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure. Belongs to the IL-4/IL-13 family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: extracellular region; extracellular space

Molecular Function: interleukin-13 receptor binding; protein binding

Biological Process: cell motility; cell-cell signaling; positive regulation of B cell proliferation; positive regulation of immunoglobulin production; positive regulation of macrophage activation; positive regulation of mast cell degranulation

Disease: Allergic Rhinitis; Asthma, Susceptibility To
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 Research Articles on IL13    1. IL-13 is a type 2 cytokine that is a key mediator of airway inflammation and remodeling in many inflammatory diseases of the lung, such as asthma. Read More: http://www.atsjournals.org/doi/full/10.1164/rccm.201506-1243OC#.V2bnHdLrtNs
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL13 recombinant proteinPathways associated with IL13 recombinant protein
 Reference Product  PubMed Publications
 STAT6 recombinant protein  >466 publications with IL13 and STAT6
 IL13RA1 recombinant protein  >307 publications with IL13 and IL13RA1
 IL5 recombinant protein  >169 publications with IL13 and IL5
 GATA3 recombinant protein  >116 publications with IL13 and GATA3
 IL18 recombinant protein  >100 publications with IL13 and IL18
 IL4R recombinant protein  >80 publications with IL13 and IL4R
 TSLP recombinant protein  >51 publications with IL13 and TSLP
 IL3 recombinant protein  >22 publications with IL13 and IL3
 VCAM1 recombinant protein  >6 publications with IL13 and VCAM1
 Products by Pathway  Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response Pathway antibodies  Cytokines And Inflammatory Response Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 Glucocorticoid Receptor Regulatory Network Pathway antibodies  Glucocorticoid Receptor Regulatory Network Pathway Diagram
 IL12 Signaling Mediated By STAT4 Pathway antibodies  IL12 Signaling Mediated By STAT4 Pathway Diagram
Diseases associated with IL13 recombinant proteinOrgans/Tissues associated with IL13 recombinant protein
 Disease Name  Pubmed Publications
 Hypersensitivity Antibodies  >1577 publications with IL13 and Hypersensitivity
 Inflammation Antibodies  >1562 publications with IL13 and Inflammation
 Asthma Antibodies  >1444 publications with IL13 and Asthma
 Hypersensitivity, Immediate Antibodies  >1380 publications with IL13 and Hypersensitivity, Immediate
 Lung Diseases Antibodies  >1368 publications with IL13 and Lung Diseases
 Respiratory Hypersensitivity Antibodies  >1141 publications with IL13 and Respiratory Hypersensitivity
 Necrosis Antibodies  >707 publications with IL13 and Necrosis
 Fibrosis Antibodies  >392 publications with IL13 and Fibrosis
 Bronchial Hyperreactivity Antibodies  >246 publications with IL13 and Bronchial Hyperreactivity
 Dermatitis, Atopic Antibodies  >217 publications with IL13 and Dermatitis, Atopic
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >210 publications with IL13 and Brain
 Bone Marrow Antibodies  >168 publications with IL13 and Bone Marrow
 Mixed Antibodies  >75 publications with IL13 and Mixed
 Testis Antibodies  >8 publications with IL13 and Testis
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