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IL2 recombinant protein :: Interleukin 2, Porcine Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS650222 IL2 recombinant protein
Unit / Price
0.01 mg  /  $635 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin 2, Porcine (IL2), Recombinant Protein

★Popular Item★
 Also Known As   

Interleukin 2, Recombinant, Porcine (IL-2)

 Product Gene Name   

IL2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 4; NC_000004.11 (123372625..123377650, complement). Location: 4q26-q27
 OMIM    147680
 3D Structure    ModBase 3D Structure for P60568
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 Purity/Purification    Highly Purified
>95% (SDS-PAGE)
 Form/Format    Supplied as a lyophilized powder. BSA free. Reconstitute with sterile dH2O to 0.1-1mg/ml.
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 Activity    ED50 range = 0.1-0.5ng/ml, dtermined by the dose-dependent proliferation of mouse CTLL-cells.
 Endotoxin Level    <0.1ng/ug
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 Preparation and Storage    Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of IL2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for IL2 recombinant protein

   Recombinant corresponding to porcine interleukin 2 expresses in E.coli.
 Product Categories/Family for IL2 recombinant protein    Growth Factors, Cytokines; Growth Factors-Interleukin
NCBI/Uniprot data below describe general gene information for IL2. It may not necessarily be applicable to this product.
 NCBI GI #    512412
 NCBI GeneID    3558
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 UniProt Primary Accession #    P60568 [Other Products]
 UniProt Secondary Accession #    P01585 [Other Products]
 UniProt Related Accession #    P60568; Q0GK43; Q13169; Q16334; Q309Q7; Q6NZ91; Q6NZ93; Q6QWN0; Q71V48; Q7Z7M3 [Other Products]
 Molecular Weight    ~16kD [Similar Products]
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 NCBI Official Full Name    interleukin-2
 NCBI Official Synonym Full Names    interleukin 2
 NCBI Official Symbol    IL2 [Similar Products]
 NCBI Official Synonym Symbols   
IL-2; TCGF; lymphokine
[Similar Products]
 NCBI Protein Information    interleukin-2; aldesleukin; OTTHUMP00000164090; T cell growth factor; involved in regulation of T-cell clonal expansion
 UniProt Protein Name    Interleukin-2
 UniProt Synonym Protein Names   
T-cell growth factor
 Protein Family    Interleukin
 UniProt Gene Name    IL2 [Similar Products]
 UniProt Entry Name    IL2_HUMAN
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 NCBI Summary for IL2    The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq]
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 UniProt Comments for IL2    Function: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.

Subcellular location: Secreted.

Involvement in disease: Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.

Pharmaceutical use: Available under the name Proleukin (Chiron). Used in patients with renal cell carcinoma or metastatic melanoma.

Sequence similarities: Belongs to the IL-2 family.

Sequence caution: The sequence AAA59140.1 differs from that shown. Reason: Erroneous initiation.
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 Research Articles on IL2    1. Data show there was a significant decrease in Th1 intracellular cytokines IFNgamma, IL-2 and TNFalpha in the blood of culture positive patients compared with culture negative patients.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL2 recombinant proteinPathways associated with IL2 recombinant protein
 Reference Product  PubMed Publications
 IL2RA recombinant protein  >68 publications with IL2 and IL2RA
 IL2RB recombinant protein  >28 publications with IL2 and IL2RB
 IL2RG recombinant protein  >5 publications with IL2 and IL2RG
 NGFR recombinant protein  >1 publications with IL2 and NGFR
 Products by Pathway  Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies  Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
 Calcium Signaling In The CD4+ TCR Pathway antibodies  Calcium Signaling In The CD4+ TCR Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
Diseases associated with IL2 recombinant proteinOrgans/Tissues associated with IL2 recombinant protein
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >699 publications with IL2 and Neoplasms
 Necrosis Antibodies  >244 publications with IL2 and Necrosis
 Autoimmune Diseases Antibodies  >203 publications with IL2 and Autoimmune Diseases
 Leukemia Antibodies  >198 publications with IL2 and Leukemia
 Carcinoma Antibodies  >171 publications with IL2 and Carcinoma
 Lymphoma Antibodies  >146 publications with IL2 and Lymphoma
 Neoplasms, Experimental Antibodies  >129 publications with IL2 and Neoplasms, Experimental
 Inflammation Antibodies  >126 publications with IL2 and Inflammation
 Melanoma Antibodies  >102 publications with IL2 and Melanoma
 Kidney Diseases Antibodies  >94 publications with IL2 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1837 publications with IL2 and Blood
 Uncharacterized Tissue Antibodies  >1 publications with IL2 and Uncharacterized Tissue
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