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Il2ra recombinant protein :: Interleukin-2 receptor subunit alpha (Il2ra) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS954131 Il2ra recombinant protein
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin-2 receptor subunit alpha (Il2ra), Recombinant Protein

 Also Known As   

Recombinant Mouse Interleukin-2 receptor subunit alpha (Il2ra)

 Product Synonym Names    Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; p55; CD_antigen=; CD25
 Product Gene Name   

Il2ra recombinant protein

[Similar Products]
 Product Synonym Gene Name    Il2ra; Il2r [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    22-236
 Sequence    ELCLYDPPE VPNATFKALS YKNGTILNCE CKRGFRRLKE LVYMRCLGNS WSSNCQCTSN SHDKSRKQVT AQLEHQKEQQ TTTDMQKPTQ SMHQENLTGH CREPPPWKHE DSKRIYHFVE GQSVHYECIP GYKALQRGPA ISICKMKCGK TGWTQPQLTC VDEREHHRFL ASEESQGSRN SSPESETSCP ITTTDFPQPT ETTAMTETFV LTMEYK
 3D Structure    ModBase 3D Structure for P01590
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Il2ra recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Il2ra. It may not necessarily be applicable to this product.
 NCBI GI #    254540187
 NCBI GeneID    16184
 NCBI Accession #    NP_032393.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_008367.3 [Other Products]
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 UniProt Primary Accession #    P01590 [Other Products]
 UniProt Secondary Accession #    Q61731 [Other Products]
 UniProt Related Accession #    P01590 [Other Products]
 Molecular Weight    30,723 Da
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 NCBI Official Full Name    interleukin-2 receptor subunit alpha
 NCBI Official Synonym Full Names    interleukin 2 receptor, alpha chain
 NCBI Official Symbol    Il2ra [Similar Products]
 NCBI Official Synonym Symbols   
CD25; Il2r; Ly-43
[Similar Products]
 NCBI Protein Information    interleukin-2 receptor subunit alpha; IL2-RA; IL-2-RA; p55 chain; IL-2R alpha chain; IL-2R subunit alpha; IL-2 receptor subunit alpha
 UniProt Protein Name    Interleukin-2 receptor subunit alpha
 UniProt Synonym Protein Names   
p55; CD_antigen: CD25
 Protein Family    Interleukin-2 receptor
 UniProt Gene Name    Il2ra [Similar Products]
 UniProt Synonym Gene Names    Il2r; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA [Similar Products]
 UniProt Entry Name    IL2RA_MOUSE
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 UniProt Comments for Il2ra    IL2RA: Receptor for interleukin-2. Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.

Protein type: Membrane protein, integral

Cellular Component: cell surface; membrane; integral to membrane; external side of plasma membrane

Molecular Function: protein binding; interleukin-2 receptor activity; drug binding; interleukin-2 binding

Biological Process: Notch signaling pathway; regulation of T cell homeostatic proliferation; negative regulation of immune response; negative regulation of defense response to virus; positive regulation of activated T cell proliferation; negative regulation of lymphocyte proliferation; inflammatory response to antigenic stimulus; negative regulation of T cell proliferation; positive regulation of T cell differentiation; negative regulation of inflammatory response; positive regulation of T cell proliferation; immune response; T cell homeostasis; activated T cell apoptosis
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 Research Articles on Il2ra    1. Functional NK cell repertoires are maintained through IL-2Ralpha and Fas ligand.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Il2ra recombinant proteinPathways associated with Il2ra recombinant protein
 Reference Product  PubMed Publications
 Stat5a recombinant protein  >4 publications with Il2ra and Stat5a
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 IL-2 Signaling Pathway antibodies  IL-2 Signaling Pathway Diagram
Diseases associated with Il2ra recombinant proteinOrgans/Tissues associated with Il2ra recombinant protein
 Disease Name  Pubmed Publications
 Autoimmune Diseases Antibodies  >502 publications with Il2ra and Autoimmune Diseases
 Neoplasms Antibodies  >476 publications with Il2ra and Neoplasms
 Inflammation Antibodies  >323 publications with Il2ra and Inflammation
 Necrosis Antibodies  >249 publications with Il2ra and Necrosis
 INTERLEUKIN 2 RECEPTOR, ALPHA, DEFICIENCY OF Antibodies  >156 publications with Il2ra and INTERLEUKIN 2 RECEPTOR, ALPHA, DEFICIENCY OF
 Skin Diseases Antibodies  >133 publications with Il2ra and Skin Diseases
 Lung Diseases Antibodies  >129 publications with Il2ra and Lung Diseases
 Carcinoma Antibodies  >116 publications with Il2ra and Carcinoma
 Lymphoma Antibodies  >113 publications with Il2ra and Lymphoma
 Death Antibodies  >107 publications with Il2ra and Death
 Organ/Tissue Name  Pubmed Publications
 Spleen Antibodies  >269 publications with Il2ra and Spleen
 Lymph Node Antibodies  >210 publications with Il2ra and Lymph Node
 Thymus Antibodies  >160 publications with Il2ra and Thymus
 Skin Antibodies  >139 publications with Il2ra and Skin
 Ovary Antibodies  >9 publications with Il2ra and Ovary
 Mammary Gland Antibodies  >2 publications with Il2ra and Mammary Gland
 Uncharacterized Tissue Antibodies  >1 publications with Il2ra and Uncharacterized Tissue
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