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Il22 recombinant protein :: Interleukin-22 protein (Il22) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS969458
SDS-PAGE
Unit / Price
0.002 mg  /  $115 +1 FREE 8GB USB
0.01 mg  /  $205 +1 FREE 8GB USB
0.1 mg  /  $720 +1 FREE 8GB USB
0.25 mg  /  $1,230 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin-22 protein (Il22), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse Interleukin-22 protein (Il22) (Active)

 Product Synonym Names    IL-22; IL-TIF; IL-TIF alpha; Interleukin-22a; IL-22a
 Product Gene Name   

Il22 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Il22a; Iltif; Iltifa [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    34-179aa, Full Length of Mature Protein
 Sequence    LPVNTRCKLE VSNFQQPYIV NRTFMLAKEA SLADNNTDVR LIGEKLFRGV SAKDQCYLMK QVLNFTLEDV LLPQSDRFQP YMQEVVPFLT KLSNQLSSCH ISGDDQNIQK NVRRLKETVK KLGESGEIKA IGELDLLFMS LRNACV
 3D Structure    ModBase 3D Structure for Q9JJY9
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 Host    E Coli
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 Purity/Purification    >=96% as determined by SDS-PAGE and HPLC. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
 Biological Activity    Fully biologically active when compared to standard. The ED50 as determined by inducing IL-10 secretion of human COLO 205 cells is less than 0.2 ng/ml, corresponding to a specific activity of > 5.0 106 IU/mg.
 Storage Buffer    0.2 um filtered PBS, pH 7.4,lyophilized
 Endotoxin    Less than 1.0 EU/ug as determined by LAL method.
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 Preparation and Storage    Generally, the shelf life of liquid form is 6 months at -20/-80 degree C. The shelf life of lyophilized form is 12 months at -20/-80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Il22 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Il22 recombinant protein

   Cytokine that contributes to the inflammatory response in vivo.
 Product Categories/Family for Il22 recombinant protein    Biological Active Protein; Immunology; Interleukin
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 SDS-PAGE of Il22 recombinant protein    Il22 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Il22. It may not necessarily be applicable to this product.
 NCBI GI #    8393605
 NCBI GeneID    50929
 NCBI Accession #    NP_058667.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_016971.2 [Other Products]
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 UniProt Primary Accession #    Q9JJY9 [Other Products]
 UniProt Secondary Accession #    Q14BB3 [Other Products]
 UniProt Related Accession #    Q9JJY9 [Other Products]
 Molecular Weight    16.6 kDa
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 NCBI Official Full Name    interleukin-22
 NCBI Official Synonym Full Names    interleukin 22
 NCBI Official Symbol    Il22 [Similar Products]
 NCBI Official Synonym Symbols   
IL-22; Iltif; IL-22a; ILTIFa
[Similar Products]
 NCBI Protein Information    interleukin-22
 UniProt Protein Name    Interleukin-22
 UniProt Synonym Protein Names   
IL-10-related T-cell-derived-inducible factor; IL-TIF; IL-TIF alpha; Interleukin-22a; IL-22a
 Protein Family    Interleukin
 UniProt Gene Name    Il22 [Similar Products]
 UniProt Synonym Gene Names    Il22a; Iltif; Iltifa; IL-22; IL-TIF; IL-22a [Similar Products]
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 UniProt Comments for Il22    IL22: Cytokine that contributes to the inflammatory response in vivo. Belongs to the IL-10 family.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10 D2|10 66.67 cM

Cellular Component: extracellular space

Molecular Function: protein binding

Biological Process: negative regulation of inflammatory response; positive regulation of transcription from RNA polymerase II promoter; regulation of tyrosine phosphorylation of STAT protein
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 Research Articles on Il22    1. IL-22 inhibits acetaldehyde-induced hepatic stellate cells activation and proliferation, which may be related to nuclear translocation of Nrf2 and increased activity of the antioxidant axis Nrf2-keap1-ARE.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Il22 recombinant proteinPathways associated with Il22 recombinant protein
 Reference Product  PubMed Publications
 Il17a recombinant protein  >25 publications with Il22 and Il17a
 Stat3 recombinant protein  >18 publications with Il22 and Stat3
 Il23r recombinant protein  >10 publications with Il22 and Il23r
 Il22ra1 recombinant protein  >5 publications with Il22 and Il22ra1
 Stat1 recombinant protein  >4 publications with Il22 and Stat1
 Il10rb recombinant protein  >4 publications with Il22 and Il10rb
 Il10ra recombinant protein  >3 publications with Il22 and Il10ra
 Il22ra2 recombinant protein  >3 publications with Il22 and Il22ra2
 Ifngr2 recombinant protein  >2 publications with Il22 and Ifngr2
 Il20rb recombinant protein  >1 publications with Il22 and Il20rb
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Inflammatory Bowel Disease (IBD) Pathway antibodies  Inflammatory Bowel Disease (IBD) Pathway Diagram
 Inflammatory Bowel Disease (IBD) Pathway antibodies  Inflammatory Bowel Disease (IBD) Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
Diseases associated with Il22 recombinant proteinOrgans/Tissues associated with Il22 recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >41 publications with Il22 and Inflammation
 Colitis Antibodies  >10 publications with Il22 and Colitis
 Disease Models, Animal Antibodies  >10 publications with Il22 and Disease Models, Animal
 Lung Diseases Antibodies  >8 publications with Il22 and Lung Diseases
 Necrosis Antibodies  >6 publications with Il22 and Necrosis
 Liver Diseases Antibodies  >4 publications with Il22 and Liver Diseases
 Dermatitis Antibodies  >4 publications with Il22 and Dermatitis
 Liver Cirrhosis Antibodies  >2 publications with Il22 and Liver Cirrhosis
 Weight Loss Antibodies  >2 publications with Il22 and Weight Loss
 Fibrosis Antibodies  >2 publications with Il22 and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with Il22 and Brain
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