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IL 22 recombinant protein :: Interleukin-22 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS142205 IL 22 recombinant protein
Unit / Price
0.002 mg  /  $140 +1 FREE 8GB USB
0.01 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $4,585 +5 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin-22 (IL 22), Recombinant Protein

 Also Known As   

Recombinant Human Interleukin-22

 Product Synonym Names    IL 22 Human; Interleukin-22 Human Recombinant; IL-TIF; TIFa; IL-10-related T-cell-derived-inducible factor; IL-22; ILTIF; IL-D110; zcyto18; MGC79382; MGC79384; TIFIL-23
 Product Gene Name   

IL 22 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    The sequence of the first five N-terminal amino acids was determined and was found to be Met-Ala-Pr o-Ile-Ser
 OMIM    605330
 3D Structure    ModBase 3D Structure for Q9GZX6
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 Host    E Coli
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 Purity/Purification    Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
 Form/Format    Each mg contains 50mM Phosphate buffer pH=7.1.
Sterile Filtered White lyophilized (freeze-dried) powder.
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 Solubility    It is recommended to reconstitute the lyophilized Interleukin -22 in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
 Biological Activity    The Biological Activity was determined by the ability to activiate STAT following receptor ligand interaction.
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 Preparation and Storage    Lyophilized Interleukin-22 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution IL22 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.Please prevent freeze-thaw cycles.
 Other Notes    Small volumes of IL 22 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for IL 22 recombinant protein

   Description: Interleukin-22 Human Recombinant produced in E Coli is a single, non-glycosylated homodimeric polypeptide chain containing 2 x 146 amino acids and having a total molecular mass of 33,607 Dalton. The IL-22 is purified by proprietary chromatographic techniques.

Introduction: IL-22 is a member of the IL-10 family of regulatory cytokines.Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10R-beta/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family.
 Product Categories/Family for IL 22 recombinant protein    CYTOKINES AND GROWTH FACTORS; Cytokines; Interleukin
NCBI/Uniprot data below describe general gene information for IL 22. It may not necessarily be applicable to this product.
 NCBI GI #    10092625
 NCBI GeneID    50616
 NCBI Accession #    NP_065386.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_020525.4 [Other Products]
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 UniProt Primary Accession #    Q9GZX6 [Other Products]
 UniProt Related Accession #    Q9GZX6 [Other Products]
 Molecular Weight    20,011 Da
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 NCBI Official Full Name    interleukin-22
 NCBI Official Synonym Full Names    interleukin 22
 NCBI Official Symbol    IL22 [Similar Products]
 NCBI Official Synonym Symbols   
TIFa; IL-21; IL-22; ILTIF; IL-TIF; IL-D110; zcyto18; TIFIL-23
[Similar Products]
 NCBI Protein Information    interleukin-22; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; cytokine Zcyto18
 UniProt Protein Name    Interleukin-22
 UniProt Synonym Protein Names   
Cytokine Zcyto18; IL-10-related T-cell-derived-inducible factor; IL-TIF
 Protein Family    Interleukin
 UniProt Gene Name    IL22 [Similar Products]
 UniProt Synonym Gene Names    ILTIF; ZCYTO18; IL-22; IL-TIF [Similar Products]
 UniProt Entry Name    IL22_HUMAN
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 UniProt Comments for IL 22    IL22: Cytokine that contributes to the inflammatory response in vivo. Belongs to the IL-10 family.

Protein type: Cytokine; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 12q15

Cellular Component: extracellular space; extracellular region

Molecular Function: interleukin-22 receptor binding; cytokine activity

Biological Process: cell-cell signaling; response to glucocorticoid stimulus; acute-phase response; inflammatory response
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 Research Articles on IL 22    1. Two novel gain-of-function mutations of STAT1 responsible for chronic mucocutaneous candidiasis disease: impaired production of IL-17A and IL-22, and the presence of anti-IL-17F autoantibody.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL 22 recombinant proteinPathways associated with IL 22 recombinant protein
 Reference Product  PubMed Publications
 STAT3 recombinant protein  >11 publications with IL 22 and STAT3
 IL23A recombinant protein  >5 publications with IL 22 and IL23A
 IL22RA1 recombinant protein  >5 publications with IL 22 and IL22RA1
 IL10RB recombinant protein  >3 publications with IL 22 and IL10RB
 IL22RA2 recombinant protein  >3 publications with IL 22 and IL22RA2
 STAT1 recombinant protein  >2 publications with IL 22 and STAT1
 IL21R recombinant protein  >2 publications with IL 22 and IL21R
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Inflammatory Bowel Disease (IBD) Pathway antibodies  Inflammatory Bowel Disease (IBD) Pathway Diagram
 Inflammatory Bowel Disease (IBD) Pathway antibodies  Inflammatory Bowel Disease (IBD) Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
Diseases associated with IL 22 recombinant proteinOrgans/Tissues associated with IL 22 recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >26 publications with IL 22 and Inflammation
 Immune System Diseases Antibodies  >13 publications with IL 22 and Immune System Diseases
 Colitis Antibodies  >6 publications with IL 22 and Colitis
 Lung Diseases Antibodies  >6 publications with IL 22 and Lung Diseases
 Disease Models, Animal Antibodies  >5 publications with IL 22 and Disease Models, Animal
 Weight Loss Antibodies  >2 publications with IL 22 and Weight Loss
 Necrosis Antibodies  >2 publications with IL 22 and Necrosis
 Liver Diseases Antibodies  >2 publications with IL 22 and Liver Diseases
 Hypersensitivity Antibodies  >2 publications with IL 22 and Hypersensitivity
 Fever Antibodies  >2 publications with IL 22 and Fever
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >57 publications with IL 22 and Blood
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