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Il3ra recombinant protein :: Interleukin-3 receptor subunit alpha (Il3ra) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS954081 Il3ra recombinant protein
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin-3 receptor subunit alpha (Il3ra), Recombinant Protein

 Also Known As   

Recombinant Mouse Interleukin-3 receptor subunit alpha (Il3ra)

 Product Synonym Names    Interleukin-3 receptor subunit alpha; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA; Interleukin-3 receptor class II alpha chain; CD_antigen=; CD123
 Product Gene Name   

Il3ra recombinant protein

[Similar Products]
 Product Synonym Gene Name    Il3ra; Sut-1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    17-331
 Sequence    SDLA AVREAPPTAV TTPIQNLHID PAHYTLSWDP APGADITTGA FCRKGRDIFV WADPGLARCS FQSLSLCHVT NFTVFLGKDR AVAGSIQFPP DDDGDHEAAA QDLRCWVHEG QLSCQWERGP KATGDVHYRM FWRDVRLGPA HNRECPHYHS LDVNTAGPAP HGGHEGCTLD LDTVLGSTPN SPDLVPQVTI TVNGSGRAGP VPCMDNTVDL QRAEVLAPPT LTVECNGSEA HARWVARNRF HHGLLGYTLQ VNQSSRSEPQ EYNVSIPHFW VPNAGAISFR VKSRSEVYPR KLSSWSEAWG LVCPPEVMPV K
 3D Structure    ModBase 3D Structure for P26952
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Il3ra recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Il3ra. It may not necessarily be applicable to this product.
 NCBI GI #    6680429
 NCBI GeneID    16188
 NCBI Accession #    NP_032395.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_008369.1 [Other Products]
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 UniProt Primary Accession #    P26952 [Other Products]
 UniProt Secondary Accession #    B9VI80 [Other Products]
 UniProt Related Accession #    P26952 [Other Products]
 Molecular Weight    42,017 Da
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 NCBI Official Full Name    interleukin-3 receptor subunit alpha
 NCBI Official Synonym Full Names    interleukin 3 receptor, alpha chain
 NCBI Official Symbol    Il3ra [Similar Products]
 NCBI Official Synonym Symbols   
CD123; SUT-1; CDw123
[Similar Products]
 NCBI Protein Information    interleukin-3 receptor subunit alpha; IL-3RA; IL-3R-alpha; Il-3 alpha subunit; IL-3R subunit alpha; IL-3 receptor alpha chain; IL-3 receptor subunit alpha; IL-3 receptor alpha SP2 isoform; interleukin-3 receptor class II alpha chain
 UniProt Protein Name    Interleukin-3 receptor subunit alpha
 UniProt Synonym Protein Names   
Interleukin-3 receptor class II alpha chain; CD_antigen: CD123
 Protein Family    Interleukin-3 receptor
 UniProt Gene Name    Il3ra [Similar Products]
 UniProt Synonym Gene Names    Sut-1; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA [Similar Products]
 UniProt Entry Name    IL3RA_MOUSE
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 UniProt Comments for Il3ra    IL3RA: This is a receptor for interleukin-3. Belongs to the type I cytokine receptor family. Type 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: membrane; plasma membrane; integral to membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity
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 Research Articles on Il3ra    1. Findings indicate that SLP-76 is an essential signaling component for basophil activation downstream of both FcepsilonRI and the IL-3 receptor.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Il3ra recombinant proteinPathways associated with Il3ra recombinant protein
 Reference Product  PubMed Publications
 Csf2rb recombinant protein  >8 publications with Il3ra and Csf2rb
 Il3 recombinant protein  >7 publications with Il3ra and Il3
 Jak2 recombinant protein  >2 publications with Il3ra and Jak2
 Jak1 recombinant protein  >1 publications with Il3ra and Jak1
 Csf2rb2 recombinant protein  >1 publications with Il3ra and Csf2rb2
 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 IL-3 Signaling Pathway antibodies  IL-3 Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
Diseases associated with Il3ra recombinant proteinOrgans/Tissues associated with Il3ra recombinant protein
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >59 publications with Il3ra and Neoplasms
 Immune System Diseases Antibodies  >44 publications with Il3ra and Immune System Diseases
 Necrosis Antibodies  >9 publications with Il3ra and Necrosis
 Nervous System Diseases Antibodies  >5 publications with Il3ra and Nervous System Diseases
 Carcinoma Antibodies  >5 publications with Il3ra and Carcinoma
 Dermatitis Antibodies  >4 publications with Il3ra and Dermatitis
 Vascular Diseases Antibodies  >3 publications with Il3ra and Vascular Diseases
 Cardiovascular Diseases Antibodies  >3 publications with Il3ra and Cardiovascular Diseases
 Liver Diseases Antibodies  >2 publications with Il3ra and Liver Diseases
 Lung Diseases Antibodies  >2 publications with Il3ra and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >25 publications with Il3ra and Bone
 Bone Marrow Antibodies  >23 publications with Il3ra and Bone Marrow
 Skin Antibodies  >21 publications with Il3ra and Skin
 Embryonic Tissue Antibodies  >4 publications with Il3ra and Embryonic Tissue
 Joint Antibodies  >3 publications with Il3ra and Joint
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