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rmIL3 recombinant protein :: Interleukin-3 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS145060 rmIL3 recombinant protein
Unit / Price
0.002 mg  /  $140 +1 FREE 8GB USB
0.01 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $2,665 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin-3 (rmIL3), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Rhesus Macaque Interleukin-3

 Product Synonym Names    IL 3 Rhesus Macaque; Interleukin-3 Rhesus Macaque Recombinant; MCGF (Mast cell growth factor); Multi-CSF; HCGF; P-cell stimulation factor; IL-3; MGC79398; MGC79399
 Product Gene Name   

rmIL3 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    APMTQTTSLK TSWAKCSNMI DEIITHLNQP PLPSPDFNNL NEEDQTILVE KNLRRSNLEA FSKAVKSLQN ASAIESILKN LPPCLPMATA APTRPPIRIT NGDRNDFRRK LKFYLKTLEN EQAQ
 OMIM    147740
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 Host    E Coli
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 Purity/Purification    Greater than 97.0% as determined by SDS-PAGE.
 Form/Format    Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
Sterile Filtered White lyophilized (freeze-dried) powder.
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 Solubility    It is recommended to reconstitute the lyophilized IL-3 in sterile 18MOmega-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
 Biological Activity    The ED50 as determined by the dose-dependant stimulation of the proliferation of human TF-1 cells is less than 0.1ng/ml, corresponding to a Specific Activity of 10,000,000IU/mg.
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 Preparation and Storage    Lyophilized IL-3 Rhesus Macaque although stable at room temperature for 3 weeks, should be stored dessicated below -18 degree C. Upon reconstitution IL3 Rheus Macaque should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. Please prevent freeze-thaw cycles.
 Other Notes    Small volumes of rmIL3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for rmIL3 recombinant protein

   Description: IL 3 Rhesus Macaque Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 124 amino acids and having a molecular mass of 14.0kDa.The IL 3 Rhesus Macaque is purified by proprietary chromatographic techniques.

Introduction: IL3 is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
 Product Categories/Family for rmIL3 recombinant protein    CYTOKINES AND GROWTH FACTORS; Cytokines; Interleukin
NCBI/Uniprot data below describe general gene information for rmIL3. It may not necessarily be applicable to this product.
 NCBI GI #    28416915
 NCBI GeneID    3562
 NCBI Accession #    NP_000579.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000588.3 [Other Products]
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 UniProt Secondary Accession #    Q6GS87 [Other Products]
 UniProt Related Accession #    P08700 [Other Products]
 Molecular Weight    17,233 Da
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 NCBI Official Full Name    interleukin-3
 NCBI Official Synonym Full Names    interleukin 3
 NCBI Official Symbol    IL3 [Similar Products]
 NCBI Official Synonym Symbols   
IL-3; MCGF; MULTI-CSF
[Similar Products]
 NCBI Protein Information    interleukin-3; P-cell stimulating factor; P-cell-stimulating factor; colony-stimulating factor, multiple; hematopoietic growth factor; mast cell growth factor; mast-cell growth factor; multilineage-colony-stimulating factor; multipotential colony-stimulating factor
 UniProt Protein Name    Interleukin-3
 UniProt Synonym Protein Names   
Hematopoietic growth factor; Mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor
 Protein Family    Interleukin
 UniProt Gene Name    IL3 [Similar Products]
 UniProt Synonym Gene Names    IL-3; MCGF [Similar Products]
 UniProt Entry Name    IL3_HUMAN
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 NCBI Summary for rmIL3    The protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders. [provided by RefSeq, Jul 2008]
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 UniProt Comments for rmIL3    IL3: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family.

Protein type: Oncoprotein; Secreted; Secreted, signal peptide; Cytokine; Apoptosis; Cell cycle regulation

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: extracellular space; extracellular region

Molecular Function: interleukin-3 receptor binding; growth factor activity; cytokine activity

Biological Process: nervous system development; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of tyrosine phosphorylation of Stat5 protein; cell-cell signaling; embryonic hemopoiesis; cytokine and chemokine mediated signaling pathway; positive regulation of cell proliferation; immune response; positive regulation of myeloid leukocyte differentiation; positive regulation of DNA replication
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 Research Articles on rmIL3    1. Genetic variation in interleukin-3 gene is associated with breast cancer risk.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with rmIL3 recombinant proteinPathways associated with rmIL3 recombinant protein
 Reference Product  PubMed Publications
 IL2 recombinant protein  >84 publications with rmIL3 and IL2
 IL5 recombinant protein  >50 publications with rmIL3 and IL5
 JAK2 recombinant protein  >13 publications with rmIL3 and JAK2
 IL7 recombinant protein  >10 publications with rmIL3 and IL7
 CSF2RB recombinant protein  >10 publications with rmIL3 and CSF2RB
 IL3RA recombinant protein  >8 publications with rmIL3 and IL3RA
 FOS recombinant protein  >7 publications with rmIL3 and FOS
 GRB2 recombinant protein  >2 publications with rmIL3 and GRB2
 PIK3CA recombinant protein  >1 publications with rmIL3 and PIK3CA
 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies  Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
 Calcium Signaling In The CD4+ TCR Pathway antibodies  Calcium Signaling In The CD4+ TCR Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
Diseases associated with rmIL3 recombinant proteinOrgans/Tissues associated with rmIL3 recombinant protein
 Disease Name  Pubmed Publications
 Bone Marrow Diseases Antibodies  >42 publications with rmIL3 and Bone Marrow Diseases
 Necrosis Antibodies  >30 publications with rmIL3 and Necrosis
 Disease Models, Animal Antibodies  >30 publications with rmIL3 and Disease Models, Animal
 Lung Diseases Antibodies  >24 publications with rmIL3 and Lung Diseases
 Inflammation Antibodies  >19 publications with rmIL3 and Inflammation
 Asthma Antibodies  >17 publications with rmIL3 and Asthma
 Anemia Antibodies  >12 publications with rmIL3 and Anemia
 Nervous System Diseases Antibodies  >10 publications with rmIL3 and Nervous System Diseases
 Brain Diseases Antibodies  >8 publications with rmIL3 and Brain Diseases
 Kidney Diseases Antibodies  >6 publications with rmIL3 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >13 publications with rmIL3 and Mixed
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