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IL33 recombinant protein :: Interleukin 33 (IL33) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2009232 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment) IL33 recombinant protein
Unit / Price
0.01 mg  /  $150 +1 FREE 8GB USB
0.05 mg  /  $290 +1 FREE 8GB USB
0.1 mg  /  $450 +1 FREE 8GB USB
0.2 mg  /  $560 +1 FREE 8GB USB
0.5 mg  /  $1,080 +1 FREE 8GB USB
1 mg  /  $1,605 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin 33 (IL33), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Interleukin 33 (IL33)

 Product Gene Name   

IL33 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 9; NC_000009.11 (6215149..6257983). Location: 9p24.1
 OMIM    608678
 3D Structure    ModBase 3D Structure for O95760
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 Host    E Coli
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 Purity/Purification    > 95%
 Form/Format    Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
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 Organism    Mus musculus (Mouse)
 Expression System    Prokaryotic expression
 Residues    n/a
 Endotoxin Level    <1.0EU per 1ug (determined by the LAL method)
 Reconstitution    Reconstitute in sterile PBS, pH7.2-pH7.4.
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 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of IL33 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for IL33 recombinant protein

   About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
 Applications Tested/Suitable for IL33 recombinant protein   

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

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NCBI/Uniprot data below describe general gene information for IL33. It may not necessarily be applicable to this product.
 NCBI GI #    314122337
 NCBI GeneID    90865
 NCBI Accession #    NP_001186570.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001199641.1 [Other Products]
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 UniProt Primary Accession #    O95760 [Other Products]
 UniProt Secondary Accession #    Q2YEJ5; B4DJ35; B4E1Q9; D3DRI5; E7EAX4 [Other Products]
 UniProt Related Accession #    O95760 [Other Products]
 Molecular Weight    30,759 Da
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 NCBI Official Full Name    interleukin-33 isoform 3
 NCBI Official Synonym Full Names    interleukin 33
 NCBI Official Symbol    IL33 [Similar Products]
 NCBI Official Synonym Symbols   
DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; RP11-575C20.2
[Similar Products]
 NCBI Protein Information    interleukin-33; IL-33; IL-1F11; DVS27-related protein; interleukin-1 family member 11; nuclear factor for high endothelial venules; nuclear factor from high endothelial venules
 UniProt Protein Name    Interleukin-33
 UniProt Synonym Protein Names   
Interleukin-1 family member 11; IL-1F11; Nuclear factor from high endothelial venules
 Protein Family    Interleukin
 UniProt Gene Name    IL33 [Similar Products]
 UniProt Synonym Gene Names    C9orf26; IL1F11; NFHEV; IL-33; IL-1F11; NF-HEV [Similar Products]
 UniProt Entry Name    IL33_HUMAN
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 NCBI Summary for IL33    IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4; MIM 147780). IL33 is a ligand for IL33R (IL1RL1; MIM 601203), an IL1 family receptor that is selectively expressed on Th2 cells and mast cells (summary by Yagami et al., 2010 [PubMed 20926795]).[supplied by OMIM, Jan 2011]
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 UniProt Comments for IL33    IL33: Cytokine that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Induces T-helper type 2-associated cytokines. Belongs to the IL-1 family. Highly divergent. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: 9p24.1

Cellular Component: extracellular space; transport vesicle; chromosome; nucleus

Molecular Function: protein binding; cytokine activity

Biological Process: T-helper 2 type immune response; negative regulation of T-helper 1 type immune response; positive regulation of T-helper 2 type immune response; transcription, DNA-dependent; positive regulation of interleukin-6 production; positive regulation of immunoglobulin secretion; negative regulation of leukocyte migration; positive regulation of interleukin-4 production; negative regulation of immunoglobulin secretion; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of interferon-gamma production; positive regulation of transcription from RNA polymerase II promoter; positive regulation of interleukin-13 production; positive regulation of interleukin-5 production; positive regulation of inflammatory response; positive regulation of macrophage activation
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 Research Articles on IL33    1. The genetic variation of rs4742170 in IL33 is significantly associated with the developing of ischemic stroke.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL33 recombinant proteinPathways associated with IL33 recombinant protein
 Reference Product  PubMed Publications
 IL1RL1 recombinant protein  >117 publications with IL33 and IL1RL1
 CASP1 recombinant protein  >16 publications with IL33 and CASP1
 IL18 recombinant protein  >16 publications with IL33 and IL18
 TSLP recombinant protein  >15 publications with IL33 and TSLP
 IL25 recombinant protein  >11 publications with IL33 and IL25
 IL18R1 recombinant protein  >5 publications with IL33 and IL18R1
 VEGFA recombinant protein  >1 publications with IL33 and VEGFA
 CSF2 recombinant protein  >1 publications with IL33 and CSF2
 Products by Pathway  Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
Diseases associated with IL33 recombinant proteinOrgans/Tissues associated with IL33 recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >130 publications with IL33 and Inflammation
 Hypersensitivity, Immediate Antibodies  >65 publications with IL33 and Hypersensitivity, Immediate
 Asthma Antibodies  >65 publications with IL33 and Asthma
 Lung Diseases Antibodies  >62 publications with IL33 and Lung Diseases
 Necrosis Antibodies  >43 publications with IL33 and Necrosis
 Cardiovascular Diseases Antibodies  >34 publications with IL33 and Cardiovascular Diseases
 Heart Diseases Antibodies  >18 publications with IL33 and Heart Diseases
 Neoplasms Antibodies  >18 publications with IL33 and Neoplasms
 Dermatitis, Atopic Antibodies  >13 publications with IL33 and Dermatitis, Atopic
 Nervous System Diseases Antibodies  >11 publications with IL33 and Nervous System Diseases
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >40 publications with IL33 and Lung
 Skin Antibodies  >28 publications with IL33 and Skin
 Heart Antibodies  >27 publications with IL33 and Heart
 Vascular Antibodies  >23 publications with IL33 and Vascular
 Muscle Antibodies  >18 publications with IL33 and Muscle
 Intestine Antibodies  >13 publications with IL33 and Intestine
 Liver Antibodies  >13 publications with IL33 and Liver
 Brain Antibodies  >7 publications with IL33 and Brain
 Eye Antibodies  >6 publications with IL33 and Eye
 Connective Tissue Antibodies  >5 publications with IL33 and Connective Tissue
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