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Il6 recombinant protein :: Interleukin 6, Rat Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS651033 Il6 recombinant protein
Unit / Price
0.01 mg  /  $615 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin 6, Rat (Il6), Recombinant Protein

 Also Known As   

Interleukin 6, Recombinant, Rat (Interleukin-6, IL-6, IL6, ILg6, Ifnb2)

 Product Gene Name   

Il6 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 4; NC_005103.2 (456799..461376, complement). Location: 4q11
 3D Structure    ModBase 3D Structure for P20607
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 Purity/Purification    Highly Purified
Purified: ~98% (SDS PAGE, HPLC).
 Form/Format    Supplied as a lyophilized powder in tris buffered saline, pH7.6. Preservative free. Reconstitute with 100ul sterile dH2O.
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 Activity    ED50 of < 0.01ng/ml when assayed by proliferation of IL-6 dependent murine 7TD1 cells. This corresponds to a specific activity of 1x 08units/mg.
 Endotoxin Level    0.1ng/ug
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 Preparation and Storage    Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with 100ul sterile dH2O. Aliquot and store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of Il6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for Il6 recombinant protein    Growth Factors, Cytokines; Growth Factors-Interleukin
 Application Notes for Il6 recombinant protein    Suitable for use in Functional Assays.
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NCBI/Uniprot data below describe general gene information for Il6. It may not necessarily be applicable to this product.
 NCBI GI #    7549769
 NCBI GeneID    24498
 NCBI Accession #    NP_036721.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_012589.1 [Other Products]
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 UniProt Primary Accession #    P20607 [Other Products]
 UniProt Related Accession #    P20607 [Other Products]
 Molecular Weight    ~21.7kD (187aa) [Similar Products]
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 NCBI Official Full Name    interleukin-6
 NCBI Official Synonym Full Names    interleukin 6
 NCBI Official Symbol    Il6 [Similar Products]
 NCBI Official Synonym Symbols   
ILg6; Ifnb2
[Similar Products]
 NCBI Protein Information    interleukin-6; IL-6; Interleukin 6 (interferon, beta 2)
 UniProt Protein Name    Interleukin-6
 Protein Family    Interleukin
 UniProt Gene Name    Il6 [Similar Products]
 UniProt Synonym Gene Names    Il-6 [Similar Products]
 UniProt Entry Name    IL6_RAT
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 NCBI Summary for Il6    a cytokine involved in development and possibly in neurodegenerative processes [RGD]
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 UniProt Comments for Il6    Function: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance

Subcellular location: Secreted.

Sequence similarities: Belongs to the IL-6 superfamily.
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 Research Articles on Il6    1. Data identify IL-6 as an important target for modulation of autoimmune responses.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Il6 recombinant proteinDiseases associated with Il6 recombinant protein
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1069 publications with Il6 and Inflammation
 Neoplasms Antibodies  >539 publications with Il6 and Neoplasms
 Cardiovascular Diseases Antibodies  >454 publications with Il6 and Cardiovascular Diseases
 Lung Diseases Antibodies  >177 publications with Il6 and Lung Diseases
 Leukemia Antibodies  >133 publications with Il6 and Leukemia
 Atherosclerosis Antibodies  >126 publications with Il6 and Atherosclerosis
 Liver Diseases Antibodies  >123 publications with Il6 and Liver Diseases
 Obesity Antibodies  >122 publications with Il6 and Obesity
 Insulin Resistance Antibodies  >101 publications with Il6 and Insulin Resistance
 Kidney Diseases Antibodies  >98 publications with Il6 and Kidney Diseases
Organs/Tissues associated with Il6 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Uncharacterized Tissue Antibodies  >1 publications with Il6 and Uncharacterized Tissue
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