View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List K-Ras Recombinant Protein Catalog # MBS168638 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name K-Ras, Recombinant Protein Full Product Name Recombinant Human K-Ras Product Synonym Names Recombinant Human K-Ras Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Purity/Purification rK-Ras is expressed and purified from E. coli as a recombinant protein with purity >90% by SDS-PAGE. It has an approximate MW of 23.2 kDa including a His-tag at the N-terminus. Quantity 25 ug/vial in Tris Buffer, pH 8.0 with 0.1 M NaCl, 1 mM DTT and 10% glycerol Preparation and Storage -80 degree C; avoid freeze/thaw cycles. Shelf Life: 1 year from date of receipt under proper storage conditions; for longer term storage add 0.1% BSA Other Notes Small volumes of K-Ras recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for K-Ras recombinant protein • Recombinant protein is raised in E. coli• Protein includes a tagSmall GTP-binding proteins (or GTPases) are a family of proteins that serve as molecular regulators in signaling transduction pathways. Ras, a 21 kDa protein, regulates a variety of biological response pathways that include cell growth, cell transformation and tumor invasion. Like other small GTPases, Ras regulates molecular events by cycling between an inactive GDP-bound form and an active GTP-bound form. In its active (GTP-bound) state, Ras binds specifically to the Ras-binding domain (RBD) of Raf1 to control downstream signaling cascades. The most notable members of the Ras subfamily are H-Ras, N-Ras and K-Ras, mainly for being implicated in many types of cancer. Product Categories/Family for K-Ras recombinant protein Cell Signaling and Protein Biology; G Protein Signaling/Small GTPase Assays and Reagents; Small GTPase Research Tools; Small GTPase Recombinant Proteins Product References and Citations for K-Ras recombinant protein 1. Bar-Sagi D., and Hall A. (2000) Cell 103: 227-38.2. de Rooij J., and Bos J. L. (1997) Oncogene 14: 623-5. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP